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Bipolar disorder discovery at the nano level

Bipolar disorder discovery at the nano level

A nano-sized discovery by Northwestern Medicine ® scientists helps explain how bipolar disorder affects the brain and could one day lead to new drug therapies to treat the mental illness. Scientists used a new super-resolution imaging method — the same method recognized with the 2014 Nobel Prize in chemistry — to peer deep into brain tissue from mice with bipolar-like behaviors. Continue reading

Positive subliminal messages on aging improve physical functioning in elderly

Positive subliminal messages on aging improve physical functioning in elderly

Older individuals who are subliminally exposed to positive stereotypes about aging showed improved physical functioning that can last for several weeks, a new study led by the Yale School of Public Health has found. Continue reading

Coping techniques help patients with COPD improve mentally, physically

Coping techniques help patients with COPD improve mentally, physically

Coaching patients with chronic obstructive pulmonary disease to manage stress, practice relaxation and participate in light exercise can boost a patient’s quality of life and can even improve physical symptoms, researchers at Duke Medicine report. In a study published online Sept Continue reading

Domestic violence likely more frequent for same-sex couples

Domestic violence likely more frequent for same-sex couples

Domestic violence occurs at least as frequently, and likely even more so, between same-sex couples compared to opposite-sex couples, according to a review of literature by Northwestern Medicine® scientists. Previous studies, when analyzed together, indicate that domestic violence affects 25 percent to 75 percent of lesbian, gay and bisexual individuals. However, a lack of representative data and underreporting of abuse paints an incomplete picture of the true landscape, suggesting even higher rates. Continue reading

First blood test to diagnose depression in adults

First blood test to diagnose depression in adults

The first blood test to diagnose major depression in adults has been developed by Northwestern Medicine® scientists, a breakthrough approach that provides the first objective, scientific diagnosis for depression. The test identifies depression by measuring the levels of nine RNA blood markers. RNA molecules are the messengers that interpret the DNA genetic code and carry out its instructions. Continue reading

First blood test to diagnose depression in adults

First blood test to diagnose depression in adults

The first blood test to diagnose major depression in adults has been developed by Northwestern Medicine® scientists, a breakthrough approach that provides the first objective, scientific diagnosis for depression. The test identifies depression by measuring the levels of nine RNA blood markers. RNA molecules are the messengers that interpret the DNA genetic code and carry out its instructions. Continue reading

Maturing brain flips function of amygdala in regulating stress hormones

Maturing brain flips function of amygdala in regulating stress hormones

In contrast to evidence that the amygdala stimulates stress responses in adults, researchers at Yerkes National Primate Research Center, Emory University have found that the amygdala has an inhibitory effect on stress hormones during the early development of nonhuman primates. The results are published this week in Journal of Neuroscience . The amygdala is a region of the brain known to be important for responses to threatening situations and learning about threats Continue reading

DARPA taps Lawrence Livermore to develop world’s first neural device to restore memory

DARPA taps Lawrence Livermore to develop world’s first neural device to restore memory

The Department of Defense’s Defense Advanced Research Projects Agency (DARPA) awarded Lawrence Livermore National Laboratory (LLNL) up to $2.5 million to develop an implantable neural device with the ability to record and stimulate neurons within the brain to help restore memory, DARPA officials announced this week. The research builds on the understanding that memory is a process in which neurons in certain regions of the brain encode information, store it and retrieve it. Certain types of illnesses and injuries, including Traumatic Brain Injury (TBI), Alzheimer’s disease and epilepsy, disrupt this process and cause memory loss. Continue reading

DARPA taps Lawrence Livermore to develop world’s first neural device to restore memory

DARPA taps Lawrence Livermore to develop world’s first neural device to restore memory

The Department of Defense’s Defense Advanced Research Projects Agency (DARPA) awarded Lawrence Livermore National Laboratory (LLNL) up to $2.5 million to develop an implantable neural device with the ability to record and stimulate neurons within the brain to help restore memory, DARPA officials announced this week. The research builds on the understanding that memory is a process in which neurons in certain regions of the brain encode information, store it and retrieve it. Certain types of illnesses and injuries, including Traumatic Brain Injury (TBI), Alzheimer’s disease and epilepsy, disrupt this process and cause memory loss. Continue reading

Genetic link to autism found, known as CHD8 mutation

Genetic link to autism found, known as CHD8 mutation

In a collaboration involving 13 institutions around the world, researchers have broken new ground in understanding what causes autism. The results are being published in Cell magazine July 3, 2014: “Disruptive CHD8 Mutations Define a Subtype of Autism in Early Development.” “We finally got a clear cut case of an autism specific gene,” said Raphael Bernier, the lead author, and UW associate professor in the Department of Psychiatry and Behavioral Sciences and the clinical director of the Autism Center at Seattle Children’s. Continue reading