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First detailed picture of cancer-related cell enzyme in action on chromosome unit

First detailed picture of cancer-related cell enzyme in action on chromosome unit

A landmark study to be published in the October 30, 2014 print edition of the journal Nature provides new insight into the function of an enzyme related to the BRCA1 breast cancer protein. Continue reading

Team discovers how microbes build a powerful antibiotic

Team discovers how microbes build a powerful antibiotic

Researchers report in the journal Nature that they have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Continue reading

Team discovers how microbes build a powerful antibiotic

Team discovers how microbes build a powerful antibiotic

Researchers report in the journal Nature that they have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Their discovery solves a decades-old mystery, and opens up new avenues of research into thousands of similar molecules, many of which are likely to be medically useful Continue reading

Designer ‘barrel’ proteins created

Designer ‘barrel’ proteins created

Proteins are long linear molecules that fold up to form well-defined 3D shapes. These 3D molecular architectures are essential for biological functions such as the elasticity of skin, the digestion of food, and the transport of oxygen in blood Continue reading

Designer ‘barrel’ proteins created

Designer ‘barrel’ proteins created

Proteins are long linear molecules that fold up to form well-defined 3D shapes. These 3D molecular architectures are essential for biological functions such as the elasticity of skin, the digestion of food, and the transport of oxygen in blood Continue reading

Resetting the circadian clock: Shift workers might want to skip high-iron foods at night

Resetting the circadian clock: Shift workers might want to skip high-iron foods at night

Workers punching in for the graveyard shift may be better off not eating high-iron foods at night so they don’t disrupt the circadian clock in their livers. Continue reading

Presence of enzyme may worsen effects of spinal cord injury and impair long-term recovery

Presence of enzyme may worsen effects of spinal cord injury and impair long-term recovery

Traumatic spinal cord injury (SCI) is a devastating condition with few treatment options. Studies show that damage to the barrier separating blood from the spinal cord can contribute to the neurologic deficits that arise secondary to the initial trauma. Through a series of sophisticated experiments, researchers reporting in The American Journal of Pathology suggest that matrix metalloproteinase-3 (MMP-3) plays a pivotal role in disruption of the brain/spinal cord barrier (BSCB), cell death, and functional deficits after SCI. Continue reading

Sugared soda consumption, cell aging associated in new study

Sugared soda consumption, cell aging associated in new study

Sugar-sweetened soda consumption might promote disease independently from its role in obesity, according to UC San Francisco researchers who found in a new study that drinking sugary drinks was associated with cell aging. The study revealed that telomeres — the protective units of DNA that cap the ends of chromosomes in cells — were shorter in the white blood cells of survey participants who reported drinking more soda. Continue reading

Discovery of cellular snooze button advances cancer, biofuel research

Discovery of cellular snooze button advances cancer, biofuel research

The discovery of a cellular snooze button has allowed a team of Michigan State University scientists to potentially improve biofuel production and offer insight on the early stages of cancer. Continue reading

Universal Ebola drug target identified by researchers

Universal Ebola drug target identified by researchers

University of Utah biochemists have reported a new drug discovery tool against the Ebola virus. According to a study published in this week’s online edition of Protein Science , they have produced a molecule, known as a peptide mimic, that displays a functionally critical region of the virus that is universally conserved in all known species of Ebola. This new tool can be used as a drug target in the discovery of anti-Ebola agents that are effective against all known strains and likely future strains Continue reading