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Race a factor in mortality in heart attack patients on anti-clotting drug

Race a factor in mortality in heart attack patients on anti-clotting drug

Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack. These variants increased patients’ risk of dying in the year following a first heart attack, but they appeared to do so for different reasons depending on race, according to a study at Washington University School of Medicine in St. Louis Continue reading

Race a factor in mortality in heart attack patients on anti-clotting drug

Race a factor in mortality in heart attack patients on anti-clotting drug

Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack. These variants increased patients’ risk of dying in the year following a first heart attack, but they appeared to do so for different reasons depending on race, according to a study at Washington University School of Medicine in St. Louis Continue reading

Gene differences in yellow fever, malaria mosquitoes mapped

Gene differences in yellow fever, malaria mosquitoes mapped

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever. With the map, researchers can compare the chromosome organization and evolution between this mosquito and the major carrier of malaria, the Anopheles gambiae mosquito, to find ways to prevent diseases. Continue reading

Family violence leaves genetic imprint on children

Family violence leaves genetic imprint on children

A new Tulane University School of Medicine study finds that the more fractured families are by domestic violence or trauma, the more likely that children will bear the scars down to their DNA. Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics Continue reading

Could ‘fragile Y hypothesis’ explain chromosome loss?

Could ‘fragile Y hypothesis’ explain chromosome loss?

A UT Arlington research team says their study of genetic information from more than 4,000 beetle species has yielded a new theory about why some species lose their Y chromosome and others, such as humans, hang on to it. They call it the “fragile Y hypothesis.” The biologists’ idea is that the fate of the Y chromosome is heavily influenced by how meiosis, or the production of sperm, works in an organism Continue reading

Cellular signalling for kidney regeneration discovered

Cellular signalling for kidney regeneration discovered

Doctors and scientists have for years been astonished to observe patients with kidney disease experiencing renal regeneration. The kidney, unlike its neighbor the liver, was universally understood to be a static organ once it had fully developed. Continue reading

Cellular signalling for kidney regeneration discovered

Cellular signalling for kidney regeneration discovered

Doctors and scientists have for years been astonished to observe patients with kidney disease experiencing renal regeneration. The kidney, unlike its neighbor the liver, was universally understood to be a static organ once it had fully developed. Now a new study conducted by researchers at Sheba Medical Center, Tel Aviv University, and Stanford University turns that theory on its head by pinpointing the precise cellular signalling responsible for renal regeneration and exposing the multi-layered nature of kidney growth Continue reading

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, ​​Manel Esteller, have shown that a combination of effective drugs for Parkinson’s disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease. The results of the study are published in the journal Neuropsycopharmacology . Second leading cause of mental retardation in females Rett syndrome is the second most common cause of mental retardation in women, after Down syndrome. Continue reading

Genetic influence on pulmonary function: six further genes identified

Genetic influence on pulmonary function: six further genes identified

In an analysis of several genome-wide association studies, an international team of scientists has identified six novel gene regions that are associated with the function of the lungs. Their results have been published in the current issue of the Nature Genetics scientific journal. In their investigations or so-called genome-wide association studies, the team of researchers compared the genetic profile of study participants to the forced vital capacity (FVC), a volume parameter of lung function Continue reading

Involving a genetic health care professional may improve quality, reduce unnecessary testing

Involving a genetic health care professional may improve quality, reduce unnecessary testing

A new Moffitt Cancer Center study published Thursday in Genetics in Medicine shows that counseling from a genetic health care provider before genetic testing educates patients and may help reduce unnecessary procedures. Up to 10 percent of cancers are inherited, meaning a person was born with an abnormal gene that increases their risk for cancer Continue reading