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Genetic sequencing breakthrough to aid treatment for congenital hyperinsulinism
Dec. 27, 2012 Congenital hyperinsulinism is a genetic condition where a baby’s pancreas secretes too much insulin. It affects approximately one in 50,000 live births and in severe cases requires the surgical removal of all or part of the pancreas
Epigenetics alters genes in rheumatoid arthritis
ScienceDaily (July 3, 2012) It’s not just our DNA that makes us susceptible to disease and influences its impact and outcome. Scientists are beginning to realize more and more that important changes in genes that are unrelated to changes in the DNA sequence itself — a field of study known as epigenetics — are equally influential. A research team at the University of California, San Diego — led by Gary S.
Following the genomic pathways to stop the spread of cancer
ScienceDaily (July 3, 2012) As the Genetics Society of America’s Model Organism to Human Biology (MOHB): Cancer Genetics Meeting in Washington, D.C. drew to a close, it was clear that the mantra for drug discovery to treat cancers in the post-genomic era is pathways. Pathways are ordered series of actions that occur as cells move from one state, through a series of intermediate states, to a final action
Spinal cord injury: Human cells derived from stem cells restore movement in animal models
ScienceDaily (Mar. 3, 2011) For the first time, scientists discovered that a specific type of human cell, generated from stem cells and transplanted into spinal cord injured rats, provide tremendous benefit, not only repairing damage to the nervous system but helping the animals regain locomotor function as well. The study, published March 2 in the journal PLoS ONE , focuses on human astrocytes — the major support cells in the central nervous system — and indicates that transplantation of these cells represents a potential new avenue for the treatment of spinal cord injuries and other central nervous system disorders.
Research sheds new light on mechanisms of T-ALL, a form of leukemia that primarily affects children
Dec. 23, 2012 Acute lymphatic leukemia (ALL) is the most common cancer in children under the age of 14 years. With optimum treatment, approximately 75 percent of children are currently cured, but the treatment consists of severe chemotherapy with many side effects.
Three new genetic links to colorectal cancer
Dec. 23, 2012 Vanderbilt-Ingram Cancer Center investigators have identified three new genetic “hotspots” linked to colorectal cancer. These variants, reported Dec
Why our backs can’t read braille: Scientists map sensory nerves in mouse skin
Dec. 19, 2012 Johns Hopkins scientists have created stunning images of the branching patterns of individual sensory nerve cells. Their report, published online in the journal eLife on Dec
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