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‘Velcro protein’ found to play surprising role in cell migration

‘Velcro protein’ found to play surprising role in cell migration

Studying epithelial cells, the cell type that most commonly turns cancerous, Johns Hopkins researchers have identified a protein that causes cells to release from their neighbors and migrate away from healthy mammary, or breast, tissue in mice. They also found that deletion of a cellular “Velcro protein” does not cause the single-celled migration expected. Their results, they say, help clarify the molecular changes required for cancer cells to metastasize Continue reading

Genetic differences in female athletes with ACL injuries found in study

Genetic differences in female athletes with ACL injuries found in study

Female athletes are two-to-eight times more likely to suffer an anterior cruciate ligament (ACL) injury than males. Continue reading

‘Master regulator’ of obesity? Distant IRX3 gene appears to interact with obesity-related FTO gene mutations

‘Master regulator’ of obesity? Distant IRX3 gene appears to interact with obesity-related FTO gene mutations

Mutations within the gene FTO have been implicated as the strongest genetic determinant of obesity risk in humans, but the mechanism behind this link remained unknown. Now, an international team of scientists has discovered that the obesity-associated elements within FTO interact with IRX3, a distant gene on the genome that appears to be the functional obesity gene. Continue reading

Link between missing DNA, birth defects confirmed

Link between missing DNA, birth defects confirmed

In 2010, scientists in Italy reported that a woman and her daughter showed a puzzling array of disabilities, including epilepsy and cleft palate. Continue reading

Obesity in dads may be associated with offspring’s increased risk of disease

Obesity in dads may be associated with offspring’s increased risk of disease

Feb. 5, 2013 — A father’s obesity is one factor that may influence his children’s health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine. Continue reading

High-risk pregnancy on the rise: Older moms, larger families and heavier women are driving the need for specialty care

High-risk pregnancy on the rise: Older moms, larger families and heavier women are driving the need for specialty care

Feb. 6, 2013 — At a time when society struggles to find a definition for the “typical” American family, perinatologists at Greenwich Hospital are helping women start and grow families when a pregnancy is considered “high risk” due to age or other factors. Continue reading

New stroke gene discovery could lead to tailored treatments

New stroke gene discovery could lead to tailored treatments

Jan. 31, 2013 — A study led by King’s College London has identified a new genetic variant associated with stroke Continue reading

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Jan. Continue reading

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Jan. 31, 2013 — A New York-based physician-researcher from Touro College of Osteopathic Medicine, best known for his research into fertility and twinning, has uncovered a potential connection between autism and a specific growth protein that could eventually be used as a way to predict an infant’s propensity to later develop the disease. Continue reading

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Researcher uncovers potential cause, biomarker for autism and proposes study to investigate theory

Jan. Continue reading