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Potential biomarker to detect SCID (severe combined immunodeficiency)

Potential biomarker to detect SCID (severe combined immunodeficiency)

A genetic disease called SCID, short for severe combined immunodeficiency, forces patients to breathe filtered air and avoid human contact because their bodies’ natural defenses are too weak to fight germs. Although it affects fewer than 2,000 new births each year worldwide, SCID is a cousin to acquired immune deficiency syndrome triggered by a human immunodeficiency virus — HIV/AIDS Continue reading

Signature of aging in brain: Researchers suggest that the brain’s ‘immunological age’ is what counts

Signature of aging in brain: Researchers suggest that the brain’s ‘immunological age’ is what counts

How the brain ages is still largely an open question — in part because this organ is mostly insulated from direct contact with other systems in the body, including the blood and immune systems. In research that was recently published in Science , Weizmann Institute researchers Prof Continue reading

Surprising diversity of antibody family provides clues for HIV vaccine design

Surprising diversity of antibody family provides clues for HIV vaccine design

Scientists at The Scripps Research Institute (TSRI) have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine. “In a sense, this antibody family takes more than one shot on goal in order to hit divergent forms of HIV,” said Ian A. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends Continue reading

Immune activity shortly after surgery holds big clue to recovery rate

Immune activity shortly after surgery holds big clue to recovery rate

The millions of people who undergo major surgery each year have no way of knowing how long it will take them to recover from the operation. Continue reading

New molecule allows for up to 10-fold increase in stem cell transplants

New molecule allows for up to 10-fold increase in stem cell transplants

Investigators from the Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal have just published, in the journal Science , the announcement of the discovery of a new molecule, the first of its kind, which allows for the multiplication of stem cells in a unit of cord blood. Umbilical cord stem cells are used for transplants aimed at curing a number of blood-related diseases, including leukemia, myeloma and lymphoma. Continue reading

U.S. health system not properly designed to meet needs of patients nearing end of life, say experts

U.S. health system not properly designed to meet needs of patients nearing end of life, say experts

The U.S. health care system is not properly designed to meet the needs of patients nearing the end of life and those of their families, and major changes to the system are necessary, says a new report from the Institute of Medicine. The 21-member committee that wrote the report envisioned an approach to end-of-life care that integrates traditional medical care and social services and that is high-quality, affordable, and sustainable Continue reading

Certain gut bacteria may induce metabolic changes following exposure to artificial sweeteners

Certain gut bacteria may induce metabolic changes following exposure to artificial sweeteners

Artificial sweeteners — promoted as aids to weight loss and diabetes prevention — could actually hasten the development of glucose intolerance and metabolic disease, and they do so in a surprising way: by changing the composition and function of the gut microbiota — the substantial population of bacteria residing in our intestines. These findings, the results of experiments in mice and humans, were published September 17 in Nature . Continue reading