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Immune cell’s role in intestinal movement may lead to better understanding of irritable bowel syndrome

Immune cell’s role in intestinal movement may lead to better understanding of irritable bowel syndrome

Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS). Researchers from Penn State College of Medicine, in collaboration with other scientists, have reported the role of macrophages in regulating the contractions of the colon to push digested material through the digestive tract. The muscular lining of the intestine contains a distinct kind of macrophage, an immune system cell that helps fight infections Continue reading

Immune response to infectious disease: New findings on properdin

Immune response to infectious disease: New findings on properdin

University of Leicester researchers — including three PhD graduates — contribute significantly to knowledge in immunology University of Leicester researchers have released evidence substantiating an unexpected dual role of an important component of the immune system. Findings by researchers at the University’s Department of Infection, Immunity and Inflammation — including three PhD graduates — are published in a paper for the journal ‘Medical Microbiology and Immunology’ Continue reading

Immune response to infectious disease: New findings on properdin

Immune response to infectious disease: New findings on properdin

University of Leicester researchers — including three PhD graduates — contribute significantly to knowledge in immunology University of Leicester researchers have released evidence substantiating an unexpected dual role of an important component of the immune system. Findings by researchers at the University’s Department of Infection, Immunity and Inflammation — including three PhD graduates — are published in a paper for the journal ‘Medical Microbiology and Immunology’ Continue reading

Study of noninvasive retinal imaging device presented at Alzheimer’s conference

Study of noninvasive retinal imaging device presented at Alzheimer’s conference

A noninvasive optical imaging device developed at Cedars-Sinai can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer’s disease, according to preliminary results from investigators conducting a clinical trial in Australia. The researchers will present their findings July 15 in an oral presentation at the Alzheimer’s Association International Conference 2014 in Copenhagen, Denmark. Continue reading

New approach to identify genes poised to respond in asthma patients

New approach to identify genes poised to respond in asthma patients

In a study published in the scientific journal Nature Immunology , a group at the La Jolla Institute (LJI) led by Pandurangan Vijayanand, Ph.D. identify new genes that likely contribute to asthma, a disease that currently affects over 200 million people world wide. Continue reading

Fighting parasitic infection inadvertently unleashes dormant virus

Fighting parasitic infection inadvertently unleashes dormant virus

Signals from the immune system that help repel a common parasite inadvertently can cause a dormant viral infection to become active again, a new study shows. Further research is necessary to understand the clinical significance of the finding, but researchers at Washington University School of Medicine in St. Louis said the study helps illustrate how complex interactions between infectious agents and the immune system have the potential to affect illness. Continue reading

Virus kills triple negative breast cancer cells, tumor cells in mice

Virus kills triple negative breast cancer cells, tumor cells in mice

A virus not known to cause disease kills triple-negative breast cancer cells and killed tumors grown from these cells in mice, according to Penn State College of Medicine researchers. Understanding how the virus kills cancer may lead to new treatments for breast cancer Continue reading

New possibilities for leukemia therapy with novel mode of leukemia cell recognition

New possibilities for leukemia therapy with novel mode of leukemia cell recognition

Scientists at A*STAR’s Singapore Immunology Network (SIgN) have discovered a new class of lipids in the leukemia cells that are detected by a unique group of immune cells. Continue reading

Fecal transplants restore healthy bacteria and gut functions

Fecal transplants restore healthy bacteria and gut functions

Fecal microbiota transplantation — the process of delivering stool bacteria from a healthy donor to a patient suffering from intestinal infection with the bacterium Clostridium difficile — works by restoring healthy bacteria and functioning to the recipient’s gut, according to a study published this week in mBio ®, the online open-access journal of the American Society for Microbiology. Continue reading

Reversal of type 1 diabetes in mice may eventually help humans

Reversal of type 1 diabetes in mice may eventually help humans

Investigators at the University of Cincinnati (UC) have found a therapy that reverses new onset Type 1 diabetes in mouse models and may advance efforts in combating the disease among humans. The study, led by William Ridgway, MD, was presented Saturday, June 14, 2014, at the American Diabetes Association’s 74th Scientific Sessions in San Francisco. Continue reading