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Plvap/PV1 critical to formation of the diaphragms in endothelial cells

Plvap/PV1 critical to formation of the diaphragms in endothelial cells

Jan. 3, 2013 — Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures it forms in mammalian physiology in a study published in December by the journal Developmental Cell Continue reading

Staphylococcus aureus: Why it just gets up your nose

Staphylococcus aureus: Why it just gets up your nose

Dec. 27, 2012 — A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus ( S. Continue reading

Scientists sequence genome of pathogen responsible for pneumocystis pneumonia

Scientists sequence genome of pathogen responsible for pneumocystis pneumonia

Dec. 26, 2012 — Scientists have sequenced the genome of the fungus Pneumocystis jirovecii , an advancement that could help identify new targets for drugs to treat and prevent Pneumocystis pneumonia, a common and often deadly infection in immunocompromised patients Continue reading

Antibodies reverse type 1 diabetes in new immunotherapy animal study

Antibodies reverse type 1 diabetes in new immunotherapy animal study

ScienceDaily (July 6, 2012) — Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system. Continue reading

Pigs in southern China infected with avian flu

Pigs in southern China infected with avian flu

Dec. 19, 2012 — Researchers report for the first time the seroprevalence of three strains of avian influenza viruses in pigs in southern China, but not the H5N1 avian influenza virus. Their research, published online ahead of print in the Journal of Clinical Microbiology , has implications for efforts to protect the public health from pandemics. Continue reading

Host cholesterol secretion likely to influence gut microbiota

Host cholesterol secretion likely to influence gut microbiota

Dec. 18, 2012 — For more than half a century, researchers have known that the bacteria that colonize the gastrointestinal tract of mammals influence their host’s cholesterol metabolism. Now, Jens Walter and colleagues of the University of Nebraska show that changes in cholesterol metabolism induced by diet can alter the gut flora. Continue reading

Drug used to treat HIV might defuse deadly staph infections

Drug used to treat HIV might defuse deadly staph infections

Dec. 14, 2012 — A new study by NYU School of Medicine researchers suggests that an existing HIV drug called maraviroc could be a potential therapy for Staphylococcus aureus , a notorious and deadly pathogen linked to hundreds of thousands of hospitalizations each year. Their study is published online this week in Nature . Continue reading

Drug that may help fight Duchenne muscular dystrophy discovered

Drug that may help fight Duchenne muscular dystrophy discovered

Dec. 12, 2012 — Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, death. Now, scientists at UCLA have found a drug, already approved by the U.S Continue reading

Predator-producing bacteria may be battling in human intestines

Predator-producing bacteria may be battling in human intestines

Dec. 11, 2012 — Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say. A team led by Lora V Continue reading

New coronavirus has many potential hosts, could pass from animals to humans repeatedly

New coronavirus has many potential hosts, could pass from animals to humans repeatedly

Dec. 11, 2012 — The SARS epidemic of 2002-2003 was short-lived, but a novel type of human coronavirus that is alarming public health authorities can infect cells from humans and bats alike, a fact that could make the animals a continuing source of infection, according to a study to be published in in mBio® , the online open-access journal of the American Society for Microbiology, on December 11. Continue reading