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Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works

Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works

Scientists have solved a decades-old medical mystery — and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers say they now understand the mechanism of action of amphotericin, an antifungal drug that has been in use for more than 50 years — even though it is nearly as toxic to human cells as it is to the microbes it attacks. Continue reading

MRI pinpoints region of brain injury in some concussion patients

MRI pinpoints region of brain injury in some concussion patients

Researchers using information provided by a magnetic resonance imaging (MRI) technique have identified regional white matter damage in the brains of people who experience chronic dizziness and other symptoms after concussion. The findings suggest that information provided by MRI can speed the onset of effective treatments for concussion patients. The results of this research are published online in the journal Radiology Continue reading

MRI pinpoints region of brain injury in some concussion patients

MRI pinpoints region of brain injury in some concussion patients

Researchers using information provided by a magnetic resonance imaging (MRI) technique have identified regional white matter damage in the brains of people who experience chronic dizziness and other symptoms after concussion. The findings suggest that information provided by MRI can speed the onset of effective treatments for concussion patients. The results of this research are published online in the journal Radiology Continue reading

Experimental blood test spots recurrent breast cancers, monitors response to treatment

Experimental blood test spots recurrent breast cancers, monitors response to treatment

Johns Hopkins Kimmel Cancer Center investigators report they have designed a blood test that accurately detects the presence of advanced breast cancer and also holds promise for precisely monitoring response to cancer treatment. Continue reading

Fiber-optic microscope will help physicians detect cancer, diseases at early stages

Fiber-optic microscope will help physicians detect cancer, diseases at early stages

An engineering researcher at the University of Arkansas has developed an inexpensive, endoscopic microscope capable of producing high-resolution, sub-cellular images of tissue in real time. The fiber-optic device, which is portable, re-usable and easily packaged with conventional endoscopes, will help clinicians detect and diagnose early-stage disease, primarily cancer. Continue reading

Rare bone diseases and their dental, oral, craniofacial manifestations

Rare bone diseases and their dental, oral, craniofacial manifestations

The International and American Associations for Dental Research (IADR/AADR) have published a paper titled “Rare Bone Diseases and Their Dental, Oral, and Craniofacial Manifestations.” The complete review by researchers Sunday O. Akintoye, Andrea B Continue reading

Rare bone diseases and their dental, oral, craniofacial manifestations

Rare bone diseases and their dental, oral, craniofacial manifestations

The International and American Associations for Dental Research (IADR/AADR) have published a paper titled “Rare Bone Diseases and Their Dental, Oral, and Craniofacial Manifestations.” The complete review by researchers Sunday O. Akintoye, Andrea B. Continue reading

New mouse model could revolutionize research in Alzheimer’s disease

New mouse model could revolutionize research in Alzheimer’s disease

Alzheimer’s disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government’s annual revenues. Continue reading

New mouse model could revolutionize research in Alzheimer’s disease

New mouse model could revolutionize research in Alzheimer’s disease

Alzheimer’s disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. Continue reading

Finding the switch: Researchers create roadmap for gene expression

Finding the switch: Researchers create roadmap for gene expression

In a new study, researchers from North Carolina State University, UNC-Chapel Hill and other institutions have taken the first steps toward creating a roadmap that may help scientists narrow down the genetic cause of numerous diseases. Their work also sheds new light on how heredity and environment can affect gene expression. Continue reading