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Stem cell type resists chemotherapy drug

Stem cell type resists chemotherapy drug

A new study shows that adipose-derived human stem cells, which can become vital tissues such as bone, may be highly resistant to the common chemotherapy drug methotrexate (MTX). The preliminary finding from lab testing may prove significant because MTX causes bone tissue damage in many patients. MTX is used to treat cancers including acute lymphoblastic leukemia, the most common form of childhood cancer. Continue reading

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Individuals with celiac disease often experience ‘brain fog’ in addition to intestinal problems, but a new study shows that adhering to a gluten-free diet can lead to improvements in cognition that correlate with the extent of intestinal healing. The Alimentary Pharmacology & Therapeutics findings indicate that ridding the diet of gluten may help address problems that celiac disease patients can experience related to attention, memory, and other mental tasks Continue reading

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Individuals with celiac disease often experience ‘brain fog’ in addition to intestinal problems, but a new study shows that adhering to a gluten-free diet can lead to improvements in cognition that correlate with the extent of intestinal healing. The Alimentary Pharmacology & Therapeutics findings indicate that ridding the diet of gluten may help address problems that celiac disease patients can experience related to attention, memory, and other mental tasks. “The study outcomes highlight the importance for individuals with celiac disease of maintaining a gluten-free diet not just for physical well-being but also for mental well-being,” said senior author Dr Continue reading

E-cigarettes far less harmful than cigarettes, says researcher

E-cigarettes far less harmful than cigarettes, says researcher

A London School of Economics researcher examining the public and private dangers of drugs argues against demonizing e-cigarettes in a presentation being given at a conference of the Institute for Operations Research and the Management Sciences (INFORMS). He also calls on public officials to recognize that alcohol causes greater harm than other recreational drugs and more public attention should be paid to controlling its harmful effects Continue reading

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, ​​Manel Esteller, have shown that a combination of effective drugs for Parkinson’s disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease. The results of the study are published in the journal Neuropsycopharmacology . Second leading cause of mental retardation in females Rett syndrome is the second most common cause of mental retardation in women, after Down syndrome. Continue reading

Alcohol abuse damage in neurons at a molecular scale identified for first time

Alcohol abuse damage in neurons at a molecular scale identified for first time

Joint research between the University of the Basque Country (UPV/EHU) and the University of Nottingham has identified, for the first time, the structural damage caused at a molecular level to the brain by the chronic excessive abuse of alcohol. Continue reading

Ability to identify source of pain varies across body

Ability to identify source of pain varies across body

“Where does it hurt?” is the first question asked to any person in pain. A new UCL study defines for the first time how our ability to identify where it hurts, called “spatial acuity,” varies across the body, being most sensitive at the forehead and fingertips. Using lasers to cause pain to 26 healthy volunteers without any touch, the researchers produced the first systematic map of how acuity for pain is distributed across the body. Continue reading

Ability to identify source of pain varies across body

Ability to identify source of pain varies across body

“Where does it hurt?” is the first question asked to any person in pain. A new UCL study defines for the first time how our ability to identify where it hurts, called “spatial acuity,” varies across the body, being most sensitive at the forehead and fingertips. Using lasers to cause pain to 26 healthy volunteers without any touch, the researchers produced the first systematic map of how acuity for pain is distributed across the body. Continue reading

Drug users switch to heroin because it’s cheap, easy to get

Drug users switch to heroin because it’s cheap, easy to get

A nationwide survey indicates that heroin users are attracted to the drug not only for the “high” but because it is less expensive and easier to get than prescription painkillers. Researchers at Washington University School of Medicine in St. Continue reading

Block autophagy in multiple cancers: Trials show promise

Block autophagy in multiple cancers: Trials show promise

In the largest group of results to date, researchers from Penn Medicine’s Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine (HCQ) blocked autophagy in a host of aggressive cancers — glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers — and in some cases helped stabilize disease. Autophagy — an essential process cancer cells need to fuel their growth — is a key troublemaker spurring tumor growth. Continue reading