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Children with autism have extra synapses in brain: May be possible to prune synapses with drug after diagnosis

Children with autism have extra synapses in brain: May be possible to prune synapses with drug after diagnosis

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain “pruning” process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC). Continue reading

Novel gene predicts both breast cancer relapse, response to chemotherapy

Novel gene predicts both breast cancer relapse, response to chemotherapy

Scientists have made it easier to predict both breast cancer relapses and responses to chemotherapy, through the identification of a unique gene. Continue reading

New mouse model points to therapy for liver disease

New mouse model points to therapy for liver disease

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation Continue reading

‘Treatments waiting to be discovered’ inside new database

‘Treatments waiting to be discovered’ inside new database

Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to disease. Or what gene is regulated by a microRNA found in sick patients Continue reading

Stem cell type resists chemotherapy drug

Stem cell type resists chemotherapy drug

A new study shows that adipose-derived human stem cells, which can become vital tissues such as bone, may be highly resistant to the common chemotherapy drug methotrexate (MTX). The preliminary finding from lab testing may prove significant because MTX causes bone tissue damage in many patients. MTX is used to treat cancers including acute lymphoblastic leukemia, the most common form of childhood cancer. Continue reading

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Individuals with celiac disease often experience ‘brain fog’ in addition to intestinal problems, but a new study shows that adhering to a gluten-free diet can lead to improvements in cognition that correlate with the extent of intestinal healing. The Alimentary Pharmacology & Therapeutics findings indicate that ridding the diet of gluten may help address problems that celiac disease patients can experience related to attention, memory, and other mental tasks Continue reading

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Gluten-free diet relieves ‘brain fog’ in patients with Celiac disease

Individuals with celiac disease often experience ‘brain fog’ in addition to intestinal problems, but a new study shows that adhering to a gluten-free diet can lead to improvements in cognition that correlate with the extent of intestinal healing. The Alimentary Pharmacology & Therapeutics findings indicate that ridding the diet of gluten may help address problems that celiac disease patients can experience related to attention, memory, and other mental tasks. “The study outcomes highlight the importance for individuals with celiac disease of maintaining a gluten-free diet not just for physical well-being but also for mental well-being,” said senior author Dr Continue reading

E-cigarettes far less harmful than cigarettes, says researcher

E-cigarettes far less harmful than cigarettes, says researcher

A London School of Economics researcher examining the public and private dangers of drugs argues against demonizing e-cigarettes in a presentation being given at a conference of the Institute for Operations Research and the Management Sciences (INFORMS). He also calls on public officials to recognize that alcohol causes greater harm than other recreational drugs and more public attention should be paid to controlling its harmful effects Continue reading

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

Effective drugs for Parkinson’s reduce symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, ​​Manel Esteller, have shown that a combination of effective drugs for Parkinson’s disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease. The results of the study are published in the journal Neuropsycopharmacology . Second leading cause of mental retardation in females Rett syndrome is the second most common cause of mental retardation in women, after Down syndrome. Continue reading

Alcohol abuse damage in neurons at a molecular scale identified for first time

Alcohol abuse damage in neurons at a molecular scale identified for first time

Joint research between the University of the Basque Country (UPV/EHU) and the University of Nottingham has identified, for the first time, the structural damage caused at a molecular level to the brain by the chronic excessive abuse of alcohol. Continue reading