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Second-line afatinib significantly improves progression-free survival in recurrent or metastatic head and neck cancer, phase III trial shows

Second-line afatinib significantly improves progression-free survival in recurrent or metastatic head and neck cancer, phase III trial shows

The tyrosine kinase inhibitor afatinib significantly improved progression-free survival compared to methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after failure of platinum-based chemotherapy, the results of a phase III trial show. Continue reading

Young women with polycystic ovary syndrome are 5 times more likely to develop type 2 diabetes

Young women with polycystic ovary syndrome are 5 times more likely to develop type 2 diabetes

A leading expert on reproductive health says young women with Polycystic Ovary Syndrome (PCOS) have a startlingly higher risk of developing type 2 diabetes, even if young and not overweight. The research led by Professor Helena Teede and Dr Anju Joham, from the School of Public Health and Preventive Medicine at Monash University analysed a large-scale epidemiological study, called the Australian Longitudinal Study of Women’s Health, which revealed the findings. Over 6000 women aged between 25-28 years were monitored for nine years, including 500 with diagnosed PCOS Continue reading

Getting (drugs) under your skin: Using ultrasound waves, researchers boost skin’s permeability to drugs

Getting (drugs) under your skin: Using ultrasound waves, researchers boost skin’s permeability to drugs

ScienceDaily (Sep. Continue reading

Key to burning fat faster discovered

Key to burning fat faster discovered

ScienceDaily (Aug. 22, 2012) — Enzymes involved in breaking down fat can now be manipulated to work three times harder by turning on a molecular switch recently observed by chemists at the University of Copenhagen. Being able to control this chemical on/off button could have massive implications for curing diseases related to obesity including diabetes, cardio vascular disease, stroke and even skin problems like acne Continue reading

New type of male contraceptive? Key gene essential for sperm development discovered

New type of male contraceptive? Key gene essential for sperm development discovered

ScienceDaily (May 24, 2012) — A new type of male contraceptive could be created thanks to the discovery of a key gene essential for sperm development. The finding could lead to alternatives to the conventional male contraceptives that rely on disrupting the production of hormones, such as testosterone Continue reading

Sewage treatment plants may contribute to antibiotic resistance problem

Sewage treatment plants may contribute to antibiotic resistance problem

ScienceDaily (Dec. 7, 2011) — Water discharged into lakes and rivers from municipal sewage treatment plants may contain significant concentrations of the genes that make bacteria antibiotic-resistant. Continue reading

Pharmacists need to provide better information to teenagers on risks and benefits of medicines, review suggests

Pharmacists need to provide better information to teenagers on risks and benefits of medicines, review suggests

ScienceDaily (Sep. 4, 2011) — A large proportion of teenagers regularly and frequently take some form of medication without receiving targeted information about the risks and benefits, according to a review of current research, to be presented at the annual congress of the International Pharmaceutical Federation (FIP) on September 5. Continue reading

Curry spice could offer treatment hope for tendinitis

Curry spice could offer treatment hope for tendinitis

ScienceDaily (Aug. 9, 2011) — A derivative of a common culinary spice found in Indian curries could offer a new treatment hope for sufferers of the painful condition tendinitis, an international team of researchers has shown. In a paper due to be published in the Journal of Biological Chemistry , the researchers at The University of Nottingham and Ludwig Maximilians University in Munich have shown that curcumin, which also gives the spice turmeric its trademark bright yellow colouring, can be used to suppress biological mechanisms that spark inflammation in tendon diseases. Continue reading

Nanotubes could pose health risk to production line staff, study suggests

Nanotubes could pose health risk to production line staff, study suggests

ScienceDaily (June 14, 2011) — Tiny fibres used to strengthen items such as bike frames and hockey sticks could pose risks to workers who make them. Continue reading

Blood test markers link polycystic ovary syndrome with cardiovascular risk

Blood test markers link polycystic ovary syndrome with cardiovascular risk

ScienceDaily (May 1, 2011) — A new study presented at the European Congress of Endocrinology shows that women with polycystic ovary syndrome (PCOS) show higher levels of blood markers associated with cardiovascular disease (CVD) than control groups. These markers show up during a woman’s earlier life, but might indicate a greater CVD risk in later life. PCOS is a common ailment, affecting between 5-10% of women of reproductive age, meaning that there are millions of PCOS sufferers in Europe Continue reading