List/Grid

Laboratory Subscribe to Laboratory

Malaria pathogen’s cellular skeleton under super-microscope

Malaria pathogen’s cellular skeleton under super-microscope

The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different versions of this protein in the parasite in high detail Continue reading

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds

New therapies are needed to prevent and treat respiratory syncytial virus (RSV) — a potentially lethal respiratory infection that can severely affect infants, young children and the elderly. Despite a wide range of anti-RSV efforts, there are no vaccines or drugs on the market to effectively prevent or treat the infection. Now researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and Harvard Medical School in Boston, MA, and the James A. Continue reading

Deadly human pathogen Cryptococcus fully sequenced

Deadly human pathogen Cryptococcus fully sequenced

Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans — a fungus responsible for a million cases of pneumonia and meningitis every year — are so malleable and dangerous Continue reading

Some immune cells defend only one organ

Some immune cells defend only one organ

Scientists have uncovered a new way the immune system may fight cancers and viral infections. The finding could aid efforts to use immune cells to treat illness. Continue reading

How kids’ brain structures grow as memory develops

How kids’ brain structures grow as memory develops

Our ability to store memories improves during childhood, associated with structural changes in the hippocampus and its connections with prefrontal and parietal cortices. New research from UC Davis is exploring how these brain regions develop at this crucial time. Eventually, that could give insights into disorders that typically emerge in the transition into and during adolescence and affect memory, such as schizophrenia and depression Continue reading

How kids’ brain structures grow as memory develops

How kids’ brain structures grow as memory develops

Our ability to store memories improves during childhood, associated with structural changes in the hippocampus and its connections with prefrontal and parietal cortices. New research from UC Davis is exploring how these brain regions develop at this crucial time Continue reading

Sperm meets egg: Protein essential for fertilization discovered

Sperm meets egg: Protein essential for fertilization discovered

Researchers at the Wellcome Trust Sanger Institute have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. Continue reading

Potential use of Google Glass in surgical settings

Potential use of Google Glass in surgical settings

An article recently published in the International Journal of Surgery shows the potential applications for Google Glass in the surgical setting, particularly in relation to training. Personal portable information technology is advancing at a breathtaking speed. Continue reading

Obesity: Are lipids hard drugs for the brain?

Obesity: Are lipids hard drugs for the brain?

Why can we get up for a piece of chocolate, but never because we fancy a carrot? Serge Luquet’s team at the “Biologie Fonctionnelle et Adaptative” laboratory (CNRS/Université Paris Diderot) has demonstrated part of the answer: triglycerides, fatty substances from food, may act in our brains directly on the reward circuit, the same circuit that is involved in drug addiction. Continue reading

Experimental blood test spots recurrent breast cancers, monitors response to treatment

Experimental blood test spots recurrent breast cancers, monitors response to treatment

Johns Hopkins Kimmel Cancer Center investigators report they have designed a blood test that accurately detects the presence of advanced breast cancer and also holds promise for precisely monitoring response to cancer treatment. Continue reading