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New DNA sequencing method to diagnose tuberculosis

New DNA sequencing method to diagnose tuberculosis

Researchers working in the UK and The Gambia, have developed a new approach to the diagnosis of tuberculosis (TB) that relies on direct sequencing of DNA extracted from sputum (a technique called metagenomics) to detect and characterize the bacteria that cause TB without the need for time-consuming culture of bacteria in the laboratory. The research, reported today in the peer-reviewed journal PeerJ , was directed by Professor Mark Pallen, Professor of Microbial Genomics at Warwick Medical School and Dr Martin Antonio, head of the TB diagnostics laboratory at UK Medical Research Council (MRC) Unit in The Gambia. Continue reading

Maternal breast milk is risk factor for cytomegalovirus transmission in premature infants

Maternal breast milk is risk factor for cytomegalovirus transmission in premature infants

Premature infants, especially those born with very low-birth-weight (VLBW), are particularly vulnerable to cytomegalovirus (CMV) infection because of their immature immune systems. CMV infection can cause serious disease and, in severe cases, lead to death Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Food Memory: New discovery outlines how we remember taste experiences

Food Memory: New discovery outlines how we remember taste experiences

Have you ever eaten something totally new and it made you sick? Don’t give up; if you try the same food in a different place, your brain will be more “forgiving” of the new attempt Continue reading

New cancer drug target involving lipid chemical messengers

New cancer drug target involving lipid chemical messengers

More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood. Youhai Chen, PhD, MD, and Svetlana Fayngerts, PhD, both researchers in the department of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania, and colleagues report that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways. Lipid second messengers play cardinal roles in relaying and amplifying signals from outside the cell to its interior and outer membrane Continue reading

Genetically driven gut feelings help female flies choose a mate

Genetically driven gut feelings help female flies choose a mate

Even among flies, mating is a complicated ritual. Their elaborate, and entirely innate, courtship dance combines multiple motor skills with advanced sensory cues. Now, researchers at Rockefeller University have determined that the Abdominal-B ( Abd-B ) gene, previously known as the gene that sculpts the posterior parts of the developing fly, is also important for this complex behavior, at least in the case of female flies ( Drosophila melanogaster) Continue reading

Wireless sensor transmits tumor pressure

Wireless sensor transmits tumor pressure

The interstitial pressure inside a tumor is often remarkably high compared to normal tissues and is thought to impede the delivery of chemotherapeutic agents as well as decrease the effectiveness of radiation therapy. While medications exist that temporarily decrease tumor pressure, identifying the optimal window to initiate treatment — when tumor pressure is lowest — remains a challenge Continue reading

New biomedical implants heal bones faster, focus on personalized medicine

New biomedical implants heal bones faster, focus on personalized medicine

A major success in developing new biomedical implants with the ability to accelerate bone healing has been reported by a group of scientists from the Department of Restorative Dentistry, University of Malaya. This stems from a project partly funded by HIR and also involves Mr. Continue reading