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Finally: Missing link between vitamin D, prostate cancer

Finally: Missing link between vitamin D, prostate cancer

A University of Colorado Cancer Center study recently published in the journal Prostate offers compelling evidence that inflammation may be the link between Vitamin D and prostate cancer. Specifically, the study shows that the gene GDF-15, known to be upregulated by Vitamin D, is notably absent in samples of human prostate cancer driven by inflammation Continue reading

Real-time tracking system developed to monitor dangerous bacteria inside body

Real-time tracking system developed to monitor dangerous bacteria inside body

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections with a class of dangerous Gram-negative bacteria. These increasingly drug-resistant bacteria are responsible for a range of diseases, including fatal pneumonias and various bloodstream or solid-organ infections acquired in and outside the hospital. “What we have produced is essentially a system that localizes the epicenter of infection and provides real-time tracking of bacterial activity, giving us rapid feedback on how the bacteria respond to antibiotics,” says principal investigator Sanjay Jain, M.D., an infectious disease specialist at the Johns Hopkins Children’s Center and director of the Center for Inflammation Imaging and Research at Johns Hopkins Continue reading

Thermal paper cash register receipts account for high bisphenol A (BPA) levels  in humans

Thermal paper cash register receipts account for high bisphenol A (BPA) levels in humans

Bisphenol A (BPA) is a chemical that is used in a variety of consumer products, such as water bottles, dental composites and resins used to line metal food and beverage containers, and also is used in thermal paper cash register receipts. Now, research conducted at the University of Missouri is providing the first data that BPA from thermal paper used in cash register receipts accounts for high levels of BPA in humans. Subjects studied showed a rapid increase of BPA in their blood after using a skin care product and then touching a store receipt with BPA Continue reading

Highly effective new anti-cancer drug shows few side effects in mice

Highly effective new anti-cancer drug shows few side effects in mice

A new drug, known as OTS964, can eradicate aggressive human lung cancers transplanted into mice, according to a report in Science Translational Medicine. The drug, given as a pill or by injection, inhibits the action of a protein that is overproduced by several tumor types, including lung and breast, but is rarely expressed in healthy adult tissues Continue reading

Fast modeling of cancer mutations

Fast modeling of cancer mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process. MIT researchers have now developed a new way to model the effects of these genetic mutations in mice Continue reading

How lymph nodes expand during disease

How lymph nodes expand during disease

CANCER RESEARCH UK and UCL scientists have discovered that the same specialised immune cells that patrol the body and spot infections also trigger the expansion of immune organs called lymph nodes, according to a study published in Nature . Continue reading

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Bar attendance supports heavy drinking by young adults in the US-Mexico border region

Bar attendance supports heavy drinking by young adults in the US-Mexico border region

Due to a legal drinking age of 18 years, cheaper alcohol, and marketing tactics of local bars that specifically target youth, Mexico is an attractive and geographically nearby destination where younger U.S. residents legally drink heavily Continue reading

Bar attendance supports heavy drinking by young adults in the US-Mexico border region

Bar attendance supports heavy drinking by young adults in the US-Mexico border region

Due to a legal drinking age of 18 years, cheaper alcohol, and marketing tactics of local bars that specifically target youth, Mexico is an attractive and geographically nearby destination where younger U.S. residents legally drink heavily Continue reading