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Lab-developed intestinal organoids form mature human tissue in mice

Lab-developed intestinal organoids form mature human tissue in mice

Researchers have successfully transplanted “organoids” of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice — creating an unprecedented model for studying diseases of the intestine. Continue reading

Many older people have mutations linked to leukemia, lymphoma in their blood cells

Many older people have mutations linked to leukemia, lymphoma in their blood cells

At least 2 percent of people over age 40 and 5 percent of people over 70 have mutations linked to leukemia and lymphoma in their blood cells, according to new research at Washington University School of Medicine in St. Louis. Mutations in the body’s cells randomly accumulate as part of the aging process, and most are harmless Continue reading

‘Mega’ cells control growth of blood-producing cells

‘Mega’ cells control growth of blood-producing cells

While megakaryocytes are best known for producing platelets that heal wounds, these “mega” cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research. In fact, hematopoietic stem cells differentiate to generate megakaryocytes in bone marrow. The Stowers study is the first to show that hematopoietic stem cells (the parent cells) can be directly controlled by their own progeny (megakaryocytes). Continue reading

Research reveals likelihood, onset of multiple sclerosis diagnosis among patients with inflammatory eye disease

Research reveals likelihood, onset of multiple sclerosis diagnosis among patients with inflammatory eye disease

The results of the largest retrospective study of multiple sclerosis (MS) in uveitis patients has revealed that nearly 60 percent of patients with both diseases were diagnosed with each within a five-year span. Continue reading

Women more likely to develop anxiety and depression after heart attack

Women more likely to develop anxiety and depression after heart attack

Women are more likely to develop anxiety and depression after a heart attack (myocardial infarction; MI) than men, according to research presented at Acute Cardiovascular Care 2014 by Professor Pranas Serpytis from Lithuania. Continue reading

Using feminist theory to understand male rape

Using feminist theory to understand male rape

Decades of feminist research have framed rape and sexual assault as a ‘women’s issue’, leaving little room for the experiences of male victims. But a new study published in the Journal of Gender Studies suggests that feminist theory, with its focus on the gendered nature of rape, can also help us understand the stigmas, social constructions and realities associated with male rape Continue reading

Using feminist theory to understand male rape

Using feminist theory to understand male rape

Decades of feminist research have framed rape and sexual assault as a ‘women’s issue’, leaving little room for the experiences of male victims. Continue reading

Cystic Fibrosis lung infection: Scientists open black box on bacterial growth

Cystic Fibrosis lung infection: Scientists open black box on bacterial growth

Researchers from the University of Copenhagen have shown for the first time how bacteria can grow directly in the lungs of Cystic fibrosis patients, giving them the opportunity to get tremendous insights into bacteria behavior and growth in chronic infections. The study also discovered the bacterial growth in chronic lung infections among cystic fibrosis (CF) patients was halted or slowed down by the immune cells. The researchers discovered the immune cells consumed all the oxygen and helped “suffocate” the bacteria, forcing the bacteria to switch to a much slower growth. Continue reading

Presence of enzyme may worsen effects of spinal cord injury and impair long-term recovery

Presence of enzyme may worsen effects of spinal cord injury and impair long-term recovery

Traumatic spinal cord injury (SCI) is a devastating condition with few treatment options. Studies show that damage to the barrier separating blood from the spinal cord can contribute to the neurologic deficits that arise secondary to the initial trauma. Through a series of sophisticated experiments, researchers reporting in The American Journal of Pathology suggest that matrix metalloproteinase-3 (MMP-3) plays a pivotal role in disruption of the brain/spinal cord barrier (BSCB), cell death, and functional deficits after SCI. Continue reading

How a molecular Superman protects genome from damage

How a molecular Superman protects genome from damage

How many times have we seen Superman swoop down from the heavens and rescue a would-be victim from a rapidly oncoming train? It’s a familiar scenario, played out hundreds of times in the movies. But the dramatic scene is reenacted in real life every time a cell divides Continue reading