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Finally: Missing link between vitamin D, prostate cancer

Finally: Missing link between vitamin D, prostate cancer

A University of Colorado Cancer Center study recently published in the journal Prostate offers compelling evidence that inflammation may be the link between Vitamin D and prostate cancer. Specifically, the study shows that the gene GDF-15, known to be upregulated by Vitamin D, is notably absent in samples of human prostate cancer driven by inflammation Continue reading

Real-time tracking system developed to monitor dangerous bacteria inside body

Real-time tracking system developed to monitor dangerous bacteria inside body

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections with a class of dangerous Gram-negative bacteria. These increasingly drug-resistant bacteria are responsible for a range of diseases, including fatal pneumonias and various bloodstream or solid-organ infections acquired in and outside the hospital. “What we have produced is essentially a system that localizes the epicenter of infection and provides real-time tracking of bacterial activity, giving us rapid feedback on how the bacteria respond to antibiotics,” says principal investigator Sanjay Jain, M.D., an infectious disease specialist at the Johns Hopkins Children’s Center and director of the Center for Inflammation Imaging and Research at Johns Hopkins Continue reading

Thermal paper cash register receipts account for high bisphenol A (BPA) levels  in humans

Thermal paper cash register receipts account for high bisphenol A (BPA) levels in humans

Bisphenol A (BPA) is a chemical that is used in a variety of consumer products, such as water bottles, dental composites and resins used to line metal food and beverage containers, and also is used in thermal paper cash register receipts. Now, research conducted at the University of Missouri is providing the first data that BPA from thermal paper used in cash register receipts accounts for high levels of BPA in humans. Subjects studied showed a rapid increase of BPA in their blood after using a skin care product and then touching a store receipt with BPA Continue reading

Highly effective new anti-cancer drug shows few side effects in mice

Highly effective new anti-cancer drug shows few side effects in mice

A new drug, known as OTS964, can eradicate aggressive human lung cancers transplanted into mice, according to a report in Science Translational Medicine. The drug, given as a pill or by injection, inhibits the action of a protein that is overproduced by several tumor types, including lung and breast, but is rarely expressed in healthy adult tissues Continue reading

Fast modeling of cancer mutations

Fast modeling of cancer mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process. MIT researchers have now developed a new way to model the effects of these genetic mutations in mice Continue reading

How lymph nodes expand during disease

How lymph nodes expand during disease

CANCER RESEARCH UK and UCL scientists have discovered that the same specialised immune cells that patrol the body and spot infections also trigger the expansion of immune organs called lymph nodes, according to a study published in Nature . Continue reading

Diet for your DNA: Novel nutrition plan sparks debate around data protection

Diet for your DNA: Novel nutrition plan sparks debate around data protection

Personalized diet plans will not be widely accepted by the public until regulations are in place to protect information about our DNA, new research has shown. Led by Newcastle University, the Food4Me project is a €9 million EU project investigating the potential of nutrigenomics — a relatively new branch of nutrition which looks at how the food we eat affects the behaviour of our genes Continue reading

Novel approach for treating non-cardiac chest pain suggested

Novel approach for treating non-cardiac chest pain suggested

Chest pain doesn’t necessarily come from the heart. An estimated 200,000 Americans each year experience non-cardiac chest pain, which in addition to pain can involve painful swallowing, discomfort and anxiety. Continue reading

Cosmic rays threaten future deep-space astronaut missions

Cosmic rays threaten future deep-space astronaut missions

Crewed missions to Mars remain an essential goal for NASA, but scientists are only now beginning to understand and characterize the radiation hazards that could make such ventures risky, concludes a new paper by University of New Hampshire scientists. Continue reading

Treatment for osteoporosis, bone cancer, employed for the first time in dental filling procedures

Treatment for osteoporosis, bone cancer, employed for the first time in dental filling procedures

Journal of Dental Research publishes a paper directed by Salvatore Sauro, Professor at University CEU Cardenal Herrera in Spain, in collaboration with international researchers from Finland, Brazil, United States and United Kingdom. The research report has demonstrated how the use of zoledronic acid, in combination with bioactive ion-releasing resin-based restorative materials used as dental adhesive, reduces the degradation of dentin collagen and promotes remineralisation at the resin-dentine interface. Continue reading