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First detailed picture of cancer-related cell enzyme in action on chromosome unit

First detailed picture of cancer-related cell enzyme in action on chromosome unit

A landmark study to be published in the October 30, 2014 print edition of the journal Nature provides new insight into the function of an enzyme related to the BRCA1 breast cancer protein. Continue reading

Novel ultrasound technology to screen for heart conditions developed by engineers

Novel ultrasound technology to screen for heart conditions developed by engineers

Engineers at the University of California, San Diego have determined for the first time the impact of a ring-shaped vortex on transporting blood flow in normal and abnormal ventricles within the human heart. They worked with cardiologists at the Non-Invasive Cardiology Laboratory at Gregorio Marañon Hospital, in Madrid, Spain. In order to make the study possible, researchers have developed a novel ultrasound technology that makes screening cheaper and much easier, making it possible to reach a large number of people and even infants. Continue reading

Scientists generate first human stomach tissue in lab with stem cells

Scientists generate first human stomach tissue in lab with stem cells

Scientists used pluripotent stem cells to generate functional, three-dimensional human stomach tissue in a laboratory — creating an unprecedented tool for researching the development and diseases of an organ central to several public health crises, ranging from cancer to diabetes. Scientists at Cincinnati Children’s Hospital Medical Center report Oct. 29 in Nature they used human pluripotent stem cells — which can become any cell type in the body — to grow a miniature version of the stomach Continue reading

Governments should take active lead to create healthy food environments to prevent cardiovascular disease

Governments should take active lead to create healthy food environments to prevent cardiovascular disease

Canadian health organizations are calling upon governments to take a leadership role in creating healthy food environments. They say that implementing strategies that facilitate access to affordable healthy foods and beverages in places where Canadians work, live, and play could play a key role in preventing diet-related disease and health risk such as obesity and hypertension, and ultimately improve cardiovascular health. This call for action is published in the Canadian Journal of Cardiology Continue reading

Improving breast cancer chemo by testing patient’s tumors in a dish

Improving breast cancer chemo by testing patient’s tumors in a dish

One of the tragic realities of cancer is that the drugs used to treat it are highly toxic and their effectiveness varies unpredictably from patient to patient. However, a new “tumor-in-a-dish” technology is poised to change this reality by rapidly assessing how effective specific anti-cancer cocktails will be on an individual’s cancer before chemotherapy begins. A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks of tumors removed from patients and exposed to different anti-cancer drugs. Continue reading

European consensus on methodological recommendations for clinical studies in rare cancers

European consensus on methodological recommendations for clinical studies in rare cancers

One out of every five new cancer patients is diagnosed with a rare cancer, yet the clinical evidence needed to effectively treat these rare cancer patients is scarce. Indeed, conventional cancer clinical trial methodologies require large numbers of patients who are difficult to accrue in the situation of rare cancers. Continue reading

Mushroom extract, AHCC, helpful in treating HPV

Mushroom extract, AHCC, helpful in treating HPV

A Japanese mushroom extract appears to be effective for the eradication of human papillomavirus (HPV), according to a pilot clinical trial at The University of Texas Health Science Center at Houston (UTHealth) Medical School. The results were presented at the 11th International Conference of the Society for Integrative Oncology in Houston today by principal investigator Judith A. Smith, Pharm.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at the UTHealth Medical School. Continue reading

Ciliopathies: New insights into development

Ciliopathies: New insights into development

To date, it is still not clear how proteins regulate planar cell polarity (PCP) or the positioning of the basal body (BB) and cilia. Continue reading

Prostate cancer, kidney disease detected in urine samples on the spot

Prostate cancer, kidney disease detected in urine samples on the spot

When you flush the toilet, you may be discarding microscopic warning signs about your health. But a cunningly simple new device can stop that vital information from “going to waste.” Brigham Young University chemist Adam Woolley and his students made a device that can detect markers of kidney disease and prostate cancer in a few minutes. Continue reading