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Stochastic variations of migration speed between cells in clonal populations

Stochastic variations of migration speed between cells in clonal populations

Microfluidic tools for precision measurements of cell migration speed reveal that migratory speed of individual cells changes stochastically from parent cells to their descendants, while the average speed of the cell population remains constant through successive generations. A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of cancer cells. This tool enabled comparisons between successive generations of cells with single cell resolution. Continue reading

New discovery in the microbiology of serious human disease

New discovery in the microbiology of serious human disease

Previously undiscovered secrets of how human cells interact with a bacterium which causes a serious human disease have been revealed in new research by microbiologists at The University of Nottingham. The scientists at the University’s Centre for Biomolecular Sciences have shed new light on how two proteins found on many human cells are targeted by the human pathogen Neisseria meningitidis which can cause life-threatening meningitis and septicaemia Continue reading

New educational modules harness power of e-learning for pancreatic cancer education

New educational modules harness power of e-learning for pancreatic cancer education

How can healthcare professionals stay on top of the ever-evolving field of pancreatic cancer? The e POSSOM ( e cancer POst Graduate School of Surgery Surgical Oncology Modules) project has launched a series of innovative educational modules to meet the educational needs of post-graduate surgical trainees looking to extend their knowledge on pancreatic cancer Continue reading

Toxicity test technology hits the market

Toxicity test technology hits the market

Technology developed by the University of Leicester to test drugs and cosmetics for the damage they do to our DNA has been launched commercially today (Friday 3 October). The University has teamed up with Cleaver Scientific Ltd., a specialist UK-based manufacturer, for the development and commercialization of high throughput systems for performing the Comet Assay. Continue reading

Discovery could prevent development of brain tumours in children

Discovery could prevent development of brain tumours in children

Scientists at the IRCM discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. Continue reading

Socioeconomic factors, fashion trends linked to increase in melanoma

Socioeconomic factors, fashion trends linked to increase in melanoma

A century’s worth of cultural and historical forces have contributed to the rise in the incidence of melanoma, including changes in fashion and clothing design, according to an intriguing, retrospective research study conducted by investigators in the Ronald O. Perelman Department of Dermatology at NYU Langone Medical Center. Continue reading

Dog’s epigenome gives clues to human cancer

Dog’s epigenome gives clues to human cancer

The bond between humans and dogs is strong and ancient. Continue reading

Decreased ability to identify odors can predict death: Olfactory dysfunction is a harbinger of mortality

Decreased ability to identify odors can predict death: Olfactory dysfunction is a harbinger of mortality

For older adults, being unable to identify scents is a strong predictor of death within five years, according to a study published October 1, 2014, in the journal PLOS ONE . Thirty-nine percent of study subjects who failed a simple smelling test died during that period, compared to 19 percent of those with moderate smell loss and just 10 percent of those with a healthy sense of smell. The hazards of smell loss were “strikingly robust,” the researchers note, above and beyond most chronic diseases. Continue reading

Fertility preservation option for young boys with cancer

Fertility preservation option for young boys with cancer

Wake Forest Baptist Medical Center is one of a few centers in the world — and the only one in North Carolina — offering young boys with cancer the opportunity to participate in a research study focused on fertility preservation and restoration. The research, conducted by the Medical Center’s Wake Forest Institute for Regenerative Medicine (WFIRM) under the direction of Anthony Atala, M.D., institute director, gives boys who have a high risk of becoming sterile the option to “bank” a small piece of testicular tissue prior to treatment. Continue reading

FDG-PET/CT shows promise for breast cancer patients younger than 40

FDG-PET/CT shows promise for breast cancer patients younger than 40

Researchers at Memorial Sloan Kettering found that PET/CT imaging of patients younger than 40 who were initially diagnosed with stage I-III breast cancer resulted in change of diagnosis. As reported in the October issue of The Journal of Nuclear Medicine , while guidelines recommend FDG-PET/CT imaging only for women with stage III breast cancer, it can also help physicians more accurately diagnose young breast cancer patients initially diagnosed with earlier stages of the disease. Continue reading