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Biologists delay the aging process by ‘remote control’

Biologists delay the aging process by ‘remote control’

UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems. Working with fruit flies, the life scientists activated a gene called AMPK that is a key energy sensor in cells; it gets activated when cellular energy levels are low Continue reading

Sex hormone levels in blood linked to risk of sudden cardiac arrest

Sex hormone levels in blood linked to risk of sudden cardiac arrest

Measuring the levels of sex hormones in patients’ blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that is fatal in 95 percent of patients. A new study, published online by the peer-reviewed journal Heart Rhythm , shows that lower levels of testosterone, the predominant male sex hormone, were found in men who had a sudden cardiac arrest. Higher levels of estradiol, the major female sex hormone, were strongly associated with greater chances of having a sudden cardiac arrest in both men and women Continue reading

Sex hormone levels in blood linked to risk of sudden cardiac arrest

Sex hormone levels in blood linked to risk of sudden cardiac arrest

Measuring the levels of sex hormones in patients’ blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that is fatal in 95 percent of patients. Continue reading

Taking a stand: Balancing the benefits, risks of physical activity in children

Taking a stand: Balancing the benefits, risks of physical activity in children

Today the Canadian Society of Exercise Physiology took a stand on the promotion of childhood physical activity and published their position and recommendations in the journal Applied Physiology, Nutrition, and Metabolism (APNM). This position stand provides an important overview of knowledge in the area of risk of physical activity for children and suggests both practical guidelines and a research agenda. Uniquely, this position stand addresses both benefits and risks of physical activity for children Continue reading

Taking pulse of aging of the brain

Taking pulse of aging of the brain

Researchers at the Beckman Institute at the University of Illinois at Urbana-Champaign have developed a new technique that can noninvasively image the pulse pressure and elasticity of the arteries of the brain, revealing correlations between arterial health and aging. Brain artery support, which makes up the cerebrovascular system, is crucial for healthy brain aging and preventing diseases like Alzheimer’s and other forms of dementia. Continue reading

Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Investigators from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) have successfully transplanted hearts from genetically engineered piglets into baboons’ abdomens and had the hearts survive for more than one year, twice as long as previously reported. This was achieved by using genetically engineered porcine donors and a more focused immunosuppression regimen in the baboon recipients, according to a study published in The Journal of Thoracic and Cardiovascular Surgery , an official publication of the American Association for Thoracic Surgery. Cardiac transplantation is the treatment of choice for end stage heart failure. Continue reading

Long antibiotic treatments: Slowly growing bacteria to blame

Long antibiotic treatments: Slowly growing bacteria to blame

Whether pneumonia or sepsis — infectious diseases are becoming increasingly difficult to treat. One reason for this is the growing antibiotic resistance. But even non-resistant bacteria can survive antibiotics for some time, and that’s why treatments need to be continued for several days or weeks Continue reading

Elusive viral ‘machine’ architecture finally rendered

Elusive viral ‘machine’ architecture finally rendered

For half a century biologists have studied the way that the lambda virus parks DNA in the chromosome of a host E. coli bacterium and later extracts it as a model reaction of genetic recombination. Continue reading

Bioengineers create functional 3-D brain-like tissue: Tissue kept alive for months

Bioengineers create functional 3-D brain-like tissue: Tissue kept alive for months

Bioengineers have created three-dimensional brain-like tissue that functions like and has structural features similar to tissue in the rat brain and that can be kept alive in the lab for more than two months. Continue reading

Does your training routine really need to be that complicated?

Does your training routine really need to be that complicated?

A new study just published in Applied Physiology, Nutrition, and Metabolism investigated the value of the Pre-Exhaustion (PreEx) training method and found that that the various arrangements of different exercise protocols is of less relevance than simply performing resistance training exercises with a high intensity of effort within any protocol. As resistance training is becoming a major intervention for health and disease prevention, improved understanding in this area is increasingly important. Continue reading