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Blood-brain barrier repair after stroke may prevent chronic brain deficits

Blood-brain barrier repair after stroke may prevent chronic brain deficits

Following ischemic stroke, the integrity of the blood-brain barrier (BBB), which prevents harmful substances such as inflammatory molecules from entering the brain, can be impaired in cerebral areas distant from initial ischemic insult. This disruptive condition, known as diaschisis, can lead to chronic post-stroke deficits, University of South Florida researchers report. In experiments using laboratory rats modeling ischemic stroke, USF investigators studied the consequences of the compromised BBB at the chronic post-stroke stage. Continue reading

Diffuse brain damage can occur with no signs of ‘concussion’ in rats, reports study

Diffuse brain damage can occur with no signs of ‘concussion’ in rats, reports study

A standard experimental model of concussion in rats causes substantial brain damage — but no behavioral changes comparable to those seen in patients with concussion, reports a study in the April issue of Neurosurgery , official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health Continue reading

Exposure to antiepileptic drug in womb linked to autism risk

Exposure to antiepileptic drug in womb linked to autism risk

Jan. 30, 2013 — Children whose mothers take the antiepileptic drug sodium valproate while pregnant are at significantly increased risk of autism and other neurodevelopmental disorders, suggests a small study published online in the Journal of Neurology Neurosurgery and Psychiatry. Continue reading

Robot allows ‘remote presence’ in programming brain and spine stimulators

Robot allows ‘remote presence’ in programming brain and spine stimulators

Jan. 16, 2013 — With the rapidly expanding use of brain and spinal cord stimulation therapy (neuromodulation), new “remote presence” technologies may help to meet the demand for experts to perform stimulator programming, reports a study in the January issue of Neurosurgery. Continue reading

Surgeons may use hand gestures to manipulate MRI images in OR

Surgeons may use hand gestures to manipulate MRI images in OR

Jan. 10, 2013 — Doctors may soon be using a system in the operating room that recognizes hand gestures as commands to tell a computer to browse and display medical images of the patient during a surgery. Continue reading

Long-term consequences for those suffering traumatic brain injury

Long-term consequences for those suffering traumatic brain injury

Jan. 4, 2013 — Researchers from the University of South Florida and colleagues at the James A. Continue reading

Rainfall, brain infection linked in sub-Saharan Africa

Rainfall, brain infection linked in sub-Saharan Africa

Jan. 4, 2013 — The amount of rainfall affects the number of infant infections leading to hydrocephalus in Uganda, according to a team of researchers who are the first to demonstrate that these brain infections are linked to climate. Continue reading

How deadly skin cancer spreads into other parts of the body

How deadly skin cancer spreads into other parts of the body

Jan. 3, 2013 — After recently announcing success in eliminating melanoma metastasis in laboratory experiments, scientists at Virginia Commonwealth University Massey Cancer Center have made another important discovery in understanding the process by which the gene mda-9/syntenin contributes to metastasis in melanoma (the spread of skin cancer) and possibly a variety of other cancers. Continue reading

Second impact syndrome in a high school football player: Researchers use imaging findings to chronicle new details

Second impact syndrome in a high school football player: Researchers use imaging findings to chronicle new details

Jan. 1, 2013 — In the January 2013 issue of the Journal of Neurosurgery: Pediatrics , physicians at the Indiana University School of Medicine and the Northwest Radiology Network (Indianapolis) report on the case of a 17-year-old high school football player with second impact syndrome (SIS). A rare and devastating traumatic brain injury, SIS occurs when a person — most often a teenager — sustains a second head injury before recovery from an earlier head injury is complete. Continue reading

The science of neurosurgical practice: Experts discuss importance of quality improvement, clinical research, patient care

The science of neurosurgical practice: Experts discuss importance of quality improvement, clinical research, patient care

Jan. Continue reading