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Single traumatic brain injury may prompt long-term neurodegeneration

Single traumatic brain injury may prompt long-term neurodegeneration

ScienceDaily (July 18, 2011) — Years after a single traumatic brain injury (TBI), survivors still show changes in their brains. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania suggest that Alzheimer’s disease-like neurodegeneration may be initiated or accelerated following a single traumatic brain injury, even in young adults. Continue reading

Novel combined therapy extends life, diminishes pain in brain cancer patients

Novel combined therapy extends life, diminishes pain in brain cancer patients

ScienceDaily (July 14, 2011) — Approximately five to ten percent of patients with primary or metastatic cancer suffer from devastating neurological complications such as headaches, seizures, confusion, difficulty swallowing and visual disturbances. Continue reading

Scientists devise way to sort brain cells for potential transplants

Scientists devise way to sort brain cells for potential transplants

ScienceDaily (July 6, 2011) — University of Florida scientists have discovered a way to separate the neural wheat from the chaff during the process of generating brain cells for potential patient therapies. Continue reading

New sealant gel is effective in closing spinal wounds following surgery, study finds

New sealant gel is effective in closing spinal wounds following surgery, study finds

ScienceDaily (June 16, 2011) — A gel that creates a watertight seal to close surgical wounds provides a significant advance in the treatment of patients following spinal procedures, effectively sealing spinal wounds 100 percent of the time, a national multicenter randomized study led by researchers at UC Davis has found. The substance, a polyethylene glycol (PEG) hydrogel sealant, plugs miniscule leaks in the thin sheath inside the spinal column that encloses the spinal cord, called the dura Continue reading

Vaccine extends recurrent glioblastoma survival rates by 2 to 3 times, study finds

Vaccine extends recurrent glioblastoma survival rates by 2 to 3 times, study finds

ScienceDaily (June 3, 2011) — In data presented at The American Society of Clinical Oncology (ASCO) Annual Meeting, cancer researchers found that the brain tumor vaccine HSPPC-96 for treating recurrent glioblastoma (GBM) has a favorable safety profile and extends survival by two to three times more than the current median survival rate. Patients in the study, conducted at University Hospitals Case Medical Center, University of California, San Francisco and Columbia University, were found to have a median survival of 11 months compared to current three to five month survival. Continue reading

Iron key to brain tumor drug delivery

Iron key to brain tumor drug delivery

ScienceDaily (June 2, 2011) — Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers. Malignant glioblastoma multiforme is a deadly brain tumor for which no long-term effective cure exists Continue reading

Iron key to brain tumor drug delivery

Iron key to brain tumor drug delivery

ScienceDaily (June 2, 2011) — Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers. Malignant glioblastoma multiforme is a deadly brain tumor for which no long-term effective cure exists Continue reading

Most children with head injuries are seen in hospitals not equipped to treat them, UK study finds

Most children with head injuries are seen in hospitals not equipped to treat them, UK study finds

ScienceDaily (May 23, 2011) — More than four fifths of children who turn up at emergency departments with head injuries in the UK are seen in hospitals which would have to transfer them if the injury was serious, reveals a study published online in Emergency Medicine Journal . Around 210,000 children attend hospital every year with a head injury and around 34,500 are admitted. A few children with serious head injuries will require emergency surgery and intensive care, and delays to the provision of this can prove fatal or result in severe disability Continue reading

Most children with head injuries are seen in hospitals not equipped to treat them, UK study finds

Most children with head injuries are seen in hospitals not equipped to treat them, UK study finds

ScienceDaily (May 23, 2011) — More than four fifths of children who turn up at emergency departments with head injuries in the UK are seen in hospitals which would have to transfer them if the injury was serious, reveals a study published online in Emergency Medicine Journal . Around 210,000 children attend hospital every year with a head injury and around 34,500 are admitted. A few children with serious head injuries will require emergency surgery and intensive care, and delays to the provision of this can prove fatal or result in severe disability Continue reading

Molecule Nutlin-3a activates a signal inducing cell death and senescence in primary brain tumors

Molecule Nutlin-3a activates a signal inducing cell death and senescence in primary brain tumors

ScienceDaily (Apr. Continue reading