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Brain’s ‘autopilot’ provides insight into early development of Alzheimer’s disease

Brain’s ‘autopilot’ provides insight into early development of Alzheimer’s disease

ScienceDaily (Mar. 3, 2011) — Watching the brain’s “autopilot” network in real time may help determine the onset of cognitive decline and potentially aid in making an early diagnosis of Alzheimer’s disease, according to researchers at Duke University Medical Center. While traditional MRI and imaging studies conducted in Alzheimer’s disease have focused on the anatomy and function of individual regions of the brain, the Duke team conducted the first study to test how the integrity of an entire brain network relates to future cognitive decline. Continue reading

Spinal cord injury: Human cells derived from stem cells restore movement in animal models

Spinal cord injury: Human cells derived from stem cells restore movement in animal models

ScienceDaily (Mar. 3, 2011) — For the first time, scientists discovered that a specific type of human cell, generated from stem cells and transplanted into spinal cord injured rats, provide tremendous benefit, not only repairing damage to the nervous system but helping the animals regain locomotor function as well. The study, published March 2 in the journal PLoS ONE , focuses on human astrocytes — the major support cells in the central nervous system — and indicates that transplantation of these cells represents a potential new avenue for the treatment of spinal cord injuries and other central nervous system disorders. Continue reading

How excess holiday eating disturbs your ‘food clock’

How excess holiday eating disturbs your ‘food clock’

Dec. Continue reading

Excessive protein synthesis linked to autistic-like behaviors, neuroscientists find

Excessive protein synthesis linked to autistic-like behaviors, neuroscientists find

Dec. 23, 2012 — Autistic-like behaviors can be partially remedied by normalizing excessive levels of protein synthesis in the brain, a team of researchers has found in a study of laboratory mice. The findings, which appear in the latest issue of Nature , provide a pathway to the creation of pharmaceuticals aimed at treating autism spectrum disorders (ASD) that are associated with diminished social interaction skills, impaired communication ability, and repetitive behaviors. Continue reading

Many causes for learning lags in tumor disorder

Many causes for learning lags in tumor disorder

Dec. 21, 2012 — The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine in St. Louis report. Continue reading

Many causes for learning lags in tumor disorder

Many causes for learning lags in tumor disorder

Dec. 21, 2012 — The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine in St. Louis report. Continue reading

New pathways that drive metastatic prostate cancer identified

New pathways that drive metastatic prostate cancer identified

Dec. 21, 2012 — Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical Investigation by researchers at the Kimmel Cancer Center at Jefferson Continue reading

Targeted therapy proves effective against brain tumors in preclinical studies

Targeted therapy proves effective against brain tumors in preclinical studies

Dec. 21, 2012 — Researchers from Roswell Park Cancer Institute (RPCI) have published findings from a preclinical study assessing the effectiveness of a small-molecule inhibitor, CFAK-Y15, in treating some brain cancers Continue reading

Better stroke care, everywhere: Study boosts local hospitals’ clotbuster use

Better stroke care, everywhere: Study boosts local hospitals’ clotbuster use

Dec. 20, 2012 — From the moment a stroke occurs, patients must race against the clock to get treatment that can prevent lasting damage. Continue reading

MRIs reveal signs of brain injuries not seen in CT scans

MRIs reveal signs of brain injuries not seen in CT scans

Dec. 18, 2012 — Hospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, the standard technique for evaluating such injuries in the emergency room, according to a clinical trial led by researchers at the University of California, San Francisco (UCSF) and the San Francisco General Hospital and Trauma Center (SFGH) Continue reading