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Brain tumor cells penetrated by tiny, degradable particles carrying genetic instructions

Brain tumor cells penetrated by tiny, degradable particles carrying genetic instructions

Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable “nanoparticles” able to carry DNA to brain cancer cells in mice. The team says the results of their proof of principle experiment suggest that such particles loaded with “death genes” might one day be given to brain cancer patients during neurosurgery to selectively kill off any remaining tumor cells without damaging normal brain tissue Continue reading

Neurologists report on promise of statins, estrogen, telemedicine in Parkinson’s

Neurologists report on promise of statins, estrogen, telemedicine in Parkinson’s

A trio of studies from the Perelman School of Medicine at the University of Pennsylvania demonstrate new approaches to understanding, treating and potentially staving off Parkinson’s disease (PD). Studies show that factors such as estrogen exposure and statin use have an impact on the onset of Parkinson’s disease. And a new look at telemedicine demonstrates feasibility in providing care for Parkinson’s patients using remote video visits to expand access and center care around the needs of Parkinson’s patients. Continue reading

Revolutionary ‘metamaterial’ has potential to reshape neurosurgery

Revolutionary ‘metamaterial’ has potential to reshape neurosurgery

The development of graphene — a highly advanced metamaterial with many unique and varied properties — may lead to exciting new applications in the diagnosis and treatment of neurological diseases, according to a report in the May issue of Neurosurgery , official journal of the Congress of Neurological Surgeons. Continue reading

Revolutionary ‘metamaterial’ has potential to reshape neurosurgery

Revolutionary ‘metamaterial’ has potential to reshape neurosurgery

The development of graphene — a highly advanced metamaterial with many unique and varied properties — may lead to exciting new applications in the diagnosis and treatment of neurological diseases, according to a report in the May issue of Neurosurgery , official journal of the Congress of Neurological Surgeons. Continue reading

Neuroimaging Technique: Live from inside the cell in real-time

Neuroimaging Technique: Live from inside the cell in real-time

A novel imaging technique provides insights into the role of redox signaling and reactive oxygen species in living neurons, in real time. Continue reading

Gene variant raises risk for aortic tear, rupture

Gene variant raises risk for aortic tear, rupture

Researchers from Yale School of Medicine and Celera Diagnostics have confirmed the significance of a genetic variant that substantially increases the risk of a frequently fatal thoracic aortic dissection or full rupture. The study appears online in PLOS ONE . Thoracic aortic aneurysms, or bulges in the artery wall, can develop without pain or other symptoms Continue reading

Outcome of stroke worse for people with infection

Outcome of stroke worse for people with infection

Infection is bad news for all of us — but it can be really serious to people who have had a stroke. Evidence is mounting that infection makes things much worse after a stroke. A team of scientists at the University of Manchester has now found a key to why and how infection is such a bad thing for stroke sufferers. Continue reading

Lifelong premature ejaculation can be treated by pelvic floor exercises

Lifelong premature ejaculation can be treated by pelvic floor exercises

A trial presented at the European Congress of Urology in Stockholm reports for the first time that pelvic floor exercises can be effective in treating premature ejaculation in men who have had lifelong problems. Premature Ejaculation (PE) affects a significant minority of men at some point in their lives. Continue reading

Online registry to drive brain disease research

Online registry to drive brain disease research

A new online project led by researchers at UC San Francisco promises to dramatically cut the time and cost of conducting clinical trials for brain diseases, while also helping scientists analyze and track the brain functions of thousands of volunteers over time. With easy online registration, the Brain Health Registry is designed to create a ready pool of research subjects for studies on neurological diseases, such as Alzheimer’s and Parkinson’s, as well as depression, post-traumatic stress disorder and many other brain ailments. Continue reading

Light-activated neurons from stem cells restore function to paralyzed muscles

Light-activated neurons from stem cells restore function to paralyzed muscles

A new way to artificially control muscles using light, with the potential to restore function to muscles paralyzed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King’s College London. The technique involves transplanting specially-designed motor neurons created from stem cells into injured nerve branches Continue reading