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Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Investigators from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) have successfully transplanted hearts from genetically engineered piglets into baboons’ abdomens and had the hearts survive for more than one year, twice as long as previously reported. This was achieved by using genetically engineered porcine donors and a more focused immunosuppression regimen in the baboon recipients, according to a study published in The Journal of Thoracic and Cardiovascular Surgery , an official publication of the American Association for Thoracic Surgery. Cardiac transplantation is the treatment of choice for end stage heart failure. Continue reading

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, MD, Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on April 29, 2014. Continue reading

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, MD, Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on April 29, 2014 Continue reading

Smoking affects heart surgery outcome even a year after quitting

Smoking affects heart surgery outcome even a year after quitting

Jan. 2, 2013 — Smoking cessation even a year prior to coronary artery bypass grafting (CABG) surgery does not fully normalize the changes smoking has made to the saphenous (leg) veins used for the surgery and may lead to later graft failure, according to a study published in the January 2013 issue of The Annals of Thoracic Surgery Continue reading

Immune system changes may drive aggressiveness of recurrent tumors

Immune system changes may drive aggressiveness of recurrent tumors

Dec. 26, 2012 — Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. Continue reading

Immune system changes may drive aggressiveness of recurrent tumors

Immune system changes may drive aggressiveness of recurrent tumors

Dec. 26, 2012 — Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. Continue reading

High Levels of Blood-Based Protein Specific to Mesothelioma

High Levels of Blood-Based Protein Specific to Mesothelioma

ScienceDaily (Oct. 10, 2012) — Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis Continue reading

Surgeons pilot expandable prosthetic valves for congenital heart disease

Surgeons pilot expandable prosthetic valves for congenital heart disease

ScienceDaily (Oct. 3, 2012) — Surgeons at Boston Children’s Hospital have successfully implanted a modified version of a expandable prosthetic heart valve in several children with mitral valve disease. Continue reading

Anemia negatively impacts heart surgery outcomes, study finds

Anemia negatively impacts heart surgery outcomes, study finds

ScienceDaily (Oct. 1, 2012) — Anemia is now confirmed as a risk factor for illness and even death following cardiac surgery, according to a study published in the October 2012 issue of The Annals of Thoracic Surgery Continue reading

Key immune cell may play role in lung cancer susceptibility

Key immune cell may play role in lung cancer susceptibility

ScienceDaily (Sep. 21, 2012) — Why do many heavy smokers evade lung cancer while others who have never lit up die of the disease? The question has vexed scientists for decades. Continue reading