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Skin cells can be engineered into pulmonary valves for pediatric patients

Skin cells can be engineered into pulmonary valves for pediatric patients

Researchers have found a way to take a pediatric patient’s skin cells, reprogram the skin cells to function as heart valvular cells, and then use the cells as part of a tissue-engineered pulmonary valve. A proof of concept study published in the September 2014 issue of The Annals of Thoracic Surgery provides more detail on this scientific development. “Current valve replacements cannot grow with patients as they age, but the use of a patient-specific pulmonary valve would introduce a ‘living’ valvular construct that should grow with the patient. Continue reading

Study questions accuracy of lung cancer screens in some geographic regions

Study questions accuracy of lung cancer screens in some geographic regions

A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common. Continue reading

New guidelines issued for managing peri- and postoperative atrial fibrillation

New guidelines issued for managing peri- and postoperative atrial fibrillation

The American Association for Thoracic Surgery (AATS) has released new evidence-based guidelines for the prevention and treatment of perioperative and postoperative atrial fibrillation (POAF) and flutter for thoracic surgical procedures. The guidelines are published in The Journal of Thoracic and Cardiovascular Surgery Continue reading

New guidelines issued for managing peri- and postoperative atrial fibrillation

New guidelines issued for managing peri- and postoperative atrial fibrillation

The American Association for Thoracic Surgery (AATS) has released new evidence-based guidelines for the prevention and treatment of perioperative and postoperative atrial fibrillation (POAF) and flutter for thoracic surgical procedures. Continue reading

Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Pigs’ hearts transplanted into baboon hosts remain viable more than a year

Investigators from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) have successfully transplanted hearts from genetically engineered piglets into baboons’ abdomens and had the hearts survive for more than one year, twice as long as previously reported. This was achieved by using genetically engineered porcine donors and a more focused immunosuppression regimen in the baboon recipients, according to a study published in The Journal of Thoracic and Cardiovascular Surgery , an official publication of the American Association for Thoracic Surgery. Cardiac transplantation is the treatment of choice for end stage heart failure. Continue reading

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, MD, Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on April 29, 2014. Continue reading

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Breath Analysis Offers Non-invasive Method to Detect Early Lung Cancer

Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, MD, Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on April 29, 2014 Continue reading

Smoking affects heart surgery outcome even a year after quitting

Smoking affects heart surgery outcome even a year after quitting

Jan. 2, 2013 — Smoking cessation even a year prior to coronary artery bypass grafting (CABG) surgery does not fully normalize the changes smoking has made to the saphenous (leg) veins used for the surgery and may lead to later graft failure, according to a study published in the January 2013 issue of The Annals of Thoracic Surgery Continue reading

Immune system changes may drive aggressiveness of recurrent tumors

Immune system changes may drive aggressiveness of recurrent tumors

Dec. 26, 2012 — Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. Continue reading

Immune system changes may drive aggressiveness of recurrent tumors

Immune system changes may drive aggressiveness of recurrent tumors

Dec. 26, 2012 — Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. Continue reading