List/Grid

Urology Subscribe to Urology

Untangling the biological effects of blue light

Untangling the biological effects of blue light

Blue light can both set the mood and set in motion important biological responses. Researchers at the University of Pennsylvania’s School of Medicine and School of Arts and Sciences have teased apart the separate biological responses of the human eye to blue light, revealing an unexpected contest for control. Their work addresses the properties of melanopsin, a light-sensitive protein in the eye that establishes the rhythm of our day-night cycle and the familiar constriction of the pupil to bright light. Continue reading

Untangling the biological effects of blue light

Untangling the biological effects of blue light

Blue light can both set the mood and set in motion important biological responses. Researchers at the University of Pennsylvania’s School of Medicine and School of Arts and Sciences have teased apart the separate biological responses of the human eye to blue light, revealing an unexpected contest for control. Continue reading

Chemical derived from broccoli sprouts shows promise in treating autism

Chemical derived from broccoli sprouts shows promise in treating autism

Results of a small clinical trial suggest that a chemical derived from broccoli sprouts — and best known for claims that it can help prevent certain cancers — may ease classic behavioral symptoms in those with autism spectrum disorders (ASDs). The study, a joint effort by scientists at MassGeneral Hospital for Children and the Johns Hopkins University School of Medicine, involved 40 teenage boys and young men, ages 13 to 27, with moderate to severe autism. In a report published online in the journal Proceedings of the National Academy of Sciences during the week of Oct Continue reading

Chemical derived from broccoli sprouts shows promise in treating autism

Chemical derived from broccoli sprouts shows promise in treating autism

Results of a small clinical trial suggest that a chemical derived from broccoli sprouts — and best known for claims that it can help prevent certain cancers — may ease classic behavioral symptoms in those with autism spectrum disorders (ASDs). The study, a joint effort by scientists at MassGeneral Hospital for Children and the Johns Hopkins University School of Medicine, involved 40 teenage boys and young men, ages 13 to 27, with moderate to severe autism. In a report published online in the journal Proceedings of the National Academy of Sciences during the week of Oct Continue reading

Drug used for another disease slows progression of Parkinson’s

Drug used for another disease slows progression of Parkinson’s

A new study from UCLA found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson’s disease in mice. The study, published in the October edition of the journal Neurotherapeutics , found that the drug, AT2101, which has also been studied for Gaucher disease, improved motor function, stopped inflammation in the brain and reduced levels of alpha-synuclein, a protein critically involved in Parkinson’s. though the exact cause of Parkinson’s is unknown, evidence points to an accumulation of alpha-synuclein, which has been found to be common to all people with the disorder Continue reading

Drug used for another disease slows progression of Parkinson’s

Drug used for another disease slows progression of Parkinson’s

A new study from UCLA found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson’s disease in mice. Continue reading

Myasthenia gravis: Efficacy of potential therapy for autoimmune disorder of muscle weakness

Myasthenia gravis: Efficacy of potential therapy for autoimmune disorder of muscle weakness

Nearly 60,000 Americans suffer from myasthenia gravis (MG), a non-inherited autoimmune form of muscle weakness. The disease has no cure, and the primary treatments are nonspecific immunosuppressants and inhibitors of the enzyme cholinesterase. Now, a pair of researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a fast-acting “vaccine” that can reverse the course of the disease in rats, and, they hope, in humans Continue reading

Study uncovers important process for immune system development

Study uncovers important process for immune system development

Research by UC Irvine immunologists reveals new information about how our immune system functions, shedding light on a vital process that determines how the body’s ability to fight infection develops. In the online version of Nature Immunology , neurology professor Dr. Continue reading

Memory loss associated with Alzheimer’s reversed: Small trial succeeds using systems approach to memory disorders

Memory loss associated with Alzheimer’s reversed: Small trial succeeds using systems approach to memory disorders

Patient one had two years of progressive memory loss. She was considering quitting her job, which involved analyzing data and writing reports, she got disoriented driving, and mixed up the names of her pets. Continue reading

Protein that causes frontotemporal dementia also implicated in Alzheimer’s disease

Protein that causes frontotemporal dementia also implicated in Alzheimer’s disease

Researchers at the Gladstone Institutes have shown that low levels of the protein progranulin in the brain can increase the formation of amyloid-beta plaques (a hallmark of Alzheimer’s disease), cause neuroinflammation, and worsen memory deficits in a mouse model of this condition. Continue reading