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Mitochondria’s role in neurodegenerative diseases clearer thanks to mouse study

Mitochondria’s role in neurodegenerative diseases clearer thanks to mouse study

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses. Researchers led by Janet Shaw, Ph.D., professor of biochemistry, found that when healthy, functioning mitochondria was prevented from moving along axons — nerve fibers that conduct electricity away from neurons — mice developed symptoms of neurodegenerative diseases. Continue reading

Professional recommendations against routine prostate cancer screening have little effect

Professional recommendations against routine prostate cancer screening have little effect

The effect of guidelines recommending that elderly men should not be routinely screened for prostate cancer “has been minimal at best,” according to a new study led by researchers at Henry Ford Hospital. The study, published as a research letter online in JAMA Internal Medicine , focused on the use of PSA — prostate-specific antigen — to test for prostate cancer. Continue reading

Can your blood type affect your memory in later years?

Can your blood type affect your memory in later years?

People with blood type AB may be more likely to develop memory loss in later years than people with other blood types, according to a study published in the September 10, 2014, online issue of Neurology ®, the medical journal of the American Academy of Neurology. AB is the least common blood type, found in about 4 percent of the U.S Continue reading

Can your blood type affect your memory in later years?

Can your blood type affect your memory in later years?

People with blood type AB may be more likely to develop memory loss in later years than people with other blood types, according to a study published in the September 10, 2014, online issue of Neurology ®, the medical journal of the American Academy of Neurology. AB is the least common blood type, found in about 4 percent of the U.S Continue reading

Potential risk factors for urinary tract infections in young girls

Potential risk factors for urinary tract infections in young girls

Young girls with an intense, red, itchy rash on their outer genital organs may be at increased risk of developing urinary tract infections (UTIs), according to new research from Wake Forest Baptist Medical Center. The treatment may be as simple as better hygiene and avoiding potential irritants such as bubble baths and swimming pools Continue reading

Children with autism have extra synapses in brain: May be possible to prune synapses with drug after diagnosis

Children with autism have extra synapses in brain: May be possible to prune synapses with drug after diagnosis

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain “pruning” process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC). Continue reading

Missing Protein Restored in Patients with Muscular Dystrophy

Missing Protein Restored in Patients with Muscular Dystrophy

When muscle cell membranes are damaged, the repair protein dysferlin is activated and reseals muscle membrane tears. If this repair protein is altered due to a genetic mutation, the body’s own “quality control” system (the so called proteasome) identifies the protein as being defective and eliminates it. Continue reading

Surprising differences in how teen athletes experience concussion

Surprising differences in how teen athletes experience concussion

With multiple concussions between the two of them, Dan Han and Lisa Koehl’s latest research interest isn’t surprising. “I played competitive soccer through high school and continue to play recreationally,” says Koehl, a doctoral candidate in the University of Kentucky’s Department of Psychology, “so I have firsthand experience with the dynamics that come into play when a teen suffers a concussion.” As a former high school assistant principal in the Chicago public school system, Han was responsible for overseeing student-athletes’ return to school after a concussion. Han left educational administration to pursue his doctorate in neuropsychology Continue reading

Tests to Diagnose Invasive Aspergillosis with 100% Accuracy

Tests to Diagnose Invasive Aspergillosis with 100% Accuracy

The fungal infection invasive aspergillosis (IA) can be life threatening, especially in patients whose immune systems are weakened by chemotherapy or immunosuppressive drugs. Despite the critical need for early detection, IA remains difficult to diagnose. A study in The Journal of Molecular Diagnostics compared three diagnostic tests and found that the combination of nucleic acid sequence-based amplification (NASBA) and real-time quantitative PCR (qPCR) detects aspergillosis with 100% accuracy. Continue reading

Less radical procedures offer similar cancer control compared to surgery for kidney cancer patients

Less radical procedures offer similar cancer control compared to surgery for kidney cancer patients

Needle-guided tumor destruction procedures offer near equivalent lengths of local cancer control compared to surgery for patients with small kidney cancer tumors, according to the results of a large study published in the journal European Urology . “If validated, these data suggest that an update to clinical guidelines would be warranted,” says the study’s lead author, R Continue reading