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Stem cells from some infertile men form germ cells when transplanted into mice

Stem cells from some infertile men form germ cells when transplanted into mice

Stem cells made from the skin of adult, infertile men yield primordial germ cells — cells that normally become sperm — when transplanted into the reproductive system of mice, according to researchers at the Stanford University School of Medicine and Montana State University. The infertile men in the study each had a type of genetic mutation that prevented them from making mature sperm — a condition called azoospermia. The research suggests that the men with azoospermia may have had germ cells at some point in their early lives, but lost them as they matured to adulthood Continue reading

Brain, cognitive reserve protect long-term against cognitive decline, MS researchers find

Brain, cognitive reserve protect long-term against cognitive decline, MS researchers find

Multiple sclerosis researchers have found that brain reserve and cognitive reserve confer a long-term protective effect against cognitive decline. James Sumowski, PhD, lead author of the article, and John DeLuca, PhD, are at Kessler Foundation. Co-authors are from the Manhattan Memory Center, New York, NY, the San Raffaele Scientific Institute, Milan, Italy, and the University of Belgrade, Serbia. Continue reading

Neurologists report on promise of statins, estrogen, telemedicine in Parkinson’s

Neurologists report on promise of statins, estrogen, telemedicine in Parkinson’s

A trio of studies from the Perelman School of Medicine at the University of Pennsylvania demonstrate new approaches to understanding, treating and potentially staving off Parkinson’s disease (PD). Studies show that factors such as estrogen exposure and statin use have an impact on the onset of Parkinson’s disease. And a new look at telemedicine demonstrates feasibility in providing care for Parkinson’s patients using remote video visits to expand access and center care around the needs of Parkinson’s patients. Continue reading

Neuroimaging Technique: Live from inside the cell in real-time

Neuroimaging Technique: Live from inside the cell in real-time

A novel imaging technique provides insights into the role of redox signaling and reactive oxygen species in living neurons, in real time. Continue reading

Outcome of stroke worse for people with infection

Outcome of stroke worse for people with infection

Infection is bad news for all of us — but it can be really serious to people who have had a stroke. Evidence is mounting that infection makes things much worse after a stroke. A team of scientists at the University of Manchester has now found a key to why and how infection is such a bad thing for stroke sufferers. Continue reading

Lifelong premature ejaculation can be treated by pelvic floor exercises

Lifelong premature ejaculation can be treated by pelvic floor exercises

A trial presented at the European Congress of Urology in Stockholm reports for the first time that pelvic floor exercises can be effective in treating premature ejaculation in men who have had lifelong problems. Premature Ejaculation (PE) affects a significant minority of men at some point in their lives. Continue reading

Online registry to drive brain disease research

Online registry to drive brain disease research

A new online project led by researchers at UC San Francisco promises to dramatically cut the time and cost of conducting clinical trials for brain diseases, while also helping scientists analyze and track the brain functions of thousands of volunteers over time. With easy online registration, the Brain Health Registry is designed to create a ready pool of research subjects for studies on neurological diseases, such as Alzheimer’s and Parkinson’s, as well as depression, post-traumatic stress disorder and many other brain ailments. Continue reading

Light-activated neurons from stem cells restore function to paralyzed muscles

Light-activated neurons from stem cells restore function to paralyzed muscles

A new way to artificially control muscles using light, with the potential to restore function to muscles paralyzed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King’s College London. The technique involves transplanting specially-designed motor neurons created from stem cells into injured nerve branches Continue reading

Patient stem cells help identify common problem in ALS

Patient stem cells help identify common problem in ALS

Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for amyotrophic lateral sclerosis (ALS) — Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital to design an initial clinical trial testing the safety of the treatment in ALS patients. The investigators all caution that a great deal needs to be done to assure the safety and efficacy of the treatment in ALS patients, before physicians should start offering it Continue reading

Morning rays keep off pounds

Morning rays keep off pounds

A surprising new strategy for managing your weight? Bright morning light. A new Northwestern Medicine® study reports the timing, intensity and duration of your light exposure during the day is linked to your weight — the first time this has been shown. Continue reading