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Tag Archives: Aids

Effective treatments available for HIV patients not eligible for efavirenz regimens

Effective treatments available for HIV patients not eligible for efavirenz regimens

A new national clinical trial found HIV drug regimens that do not include efavirenz are effective as first-line antiretroviral therapy. Continue reading

Aids origin ‘was 1920s Kinshasa’

Aids origin ‘was 1920s Kinshasa’

unable to retrieve full-text contentThe origin of the Aids pandemic has been traced back to 1920s Kinshasa, in what is now the Democratic Republic of Congo, scientists say. Continue reading

Premature deaths could be reduced by 40% over next 20 years, researchers say

Premature deaths could be reduced by 40% over next 20 years, researchers say

New research published today in The Lancet suggests that, with sustained international efforts, the number of premature deaths could be reduced by 40% over the next two decades (2010-2030), halving under-50 mortality and preventing a third of the deaths at ages 50-69 years. The findings reveal that, between 2000 and 2010, child deaths fell by one-third worldwide, helped by the fourth Millennium Development Goal (MDG) to reduce child deaths by two-thirds; and premature deaths among adults fell by one-sixth, helped by MDG 5 to reduce maternal mortality and MDG 6 to fight AIDS, malaria and other diseases. Continue reading

Americans rate losing eyesight as having greatest impact on their lives

Americans rate losing eyesight as having greatest impact on their lives

Many Americans across racial and ethnic groups describe losing eyesight as potentially having the greatest impact on their day-to-day life, more so than other conditions including: loss of limb, memory, hearing and speech (57% of African-Americans, 49% of non-Hispanic whites, 43% of Asians and 38% of Hispanics). When asked which disease or ailment is the worst that could happen to them, blindness ranked first among African-Americans followed by AIDS/HIV. Continue reading

The genetics of coping with HIV

The genetics of coping with HIV

We respond to infections in two fundamental ways. Continue reading

World Health Organization policy improves use of medicines

World Health Organization policy improves use of medicines

In this issue of PLOS Medicine , Kathleen Holloway from WHO and David Henry (University of Toronto, Canada) evaluated data on reported adherence to WHO essential medicines practices and measures of quality use of medicines from 56 low and middle income countries for 2002-2008. They compared the countries’ government-reported implementation of 36 essential medicines policies with independent survey results for 10 validated indicators of quality use of medicines (QUM) Continue reading

Offering option of initial HIV care at home increases use of antiretroviral therapy

Offering option of initial HIV care at home increases use of antiretroviral therapy

LSTM Researchers found that offering adults in Malawi optional home initiation of care following HIV self-testing resulted in a significant increase in the proportion of adults initiating antiretroviral therapy (ART) compared with standard HIV care. The results are part of a study that was funded by the Wellcome Trust and published in the July 23/30 issue of JAMA , which is HIV/AIDS themed and released early to coincide with the International AIDS Conference taking place in Melbourne, Australia next week. In 2012 it was estimated that 35 million people worldwide were living with the human immunodeficiency virus (HIV). Continue reading

Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA , a theme issue on HIV/AIDS. Patients infected with HIV demonstrate a high prevalence of nonalcoholic fatty liver disease, estimated at 30 percent to 40 percent Continue reading

Combination treatment for hep C associated with favorable response among HIV patients

Combination treatment for hep C associated with favorable response among HIV patients

HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA , a theme issue on HIV/AIDS. The issue is being released early to coincide with the International AIDS Conference Continue reading

Causes of death shifting in people with HIV

Causes of death shifting in people with HIV

HIV-positive adults in high income countries face a substantially reduced risk of death from AIDS-related causes, cardiovascular disease, and liver disease compared with a decade ago, according to a large international study published in The Lancet. The study which involved nearly 50,000 HIV-positive adults receiving care and antiretroviral therapy (ART) at more than 200 clinics across Europe, USA, and Australia found that overall death rates have almost halved since 1999, while deaths due to AIDS-related causes and cardiovascular disease have declined by around 65% and liver-related deaths by more than 50%. Although deaths from most causes declined over the study period, there was no reduction in death rates from non-AIDS cancers which remained stable over time (1.6 deaths per 1000 years 1999-2000 to 2.1 in 2009-2011) Continue reading