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Change in type of procedure most commonly used for bariatric surgery

Change in type of procedure most commonly used for bariatric surgery

In an analysis of the type of bariatric surgery procedures used in Michigan in recent years, sleeve gastrectomy (SG) surpassed Roux-en-Y gastric bypass (RYGB) in 2012 as the most common procedure performed for patients seeking this type of surgery, and SG became the predominant bariatric surgery procedure for patients with type 2 diabetes, according to a study in the September 3 issue of JAMA . Continue reading

Change in type of procedure most commonly used for bariatric surgery

Change in type of procedure most commonly used for bariatric surgery

In an analysis of the type of bariatric surgery procedures used in Michigan in recent years, sleeve gastrectomy (SG) surpassed Roux-en-Y gastric bypass (RYGB) in 2012 as the most common procedure performed for patients seeking this type of surgery, and SG became the predominant bariatric surgery procedure for patients with type 2 diabetes, according to a study in the September 3 issue of JAMA . Bariatric surgery is the most effective therapy available for significant and sustainable weight loss in patients with morbid obesity, and its use has increased during the last decade Continue reading

Increase seen in use of double mastectomy, although not associated with reduced death

Increase seen in use of double mastectomy, although not associated with reduced death

Among women diagnosed with early-stage breast cancer in California, the percentage undergoing a double mastectomy increased substantially between 1998 and 2011, although this procedure was not associated with a lower risk of death than breast-conserving surgery plus radiation, according to a study in the September 3 issue of JAMA . The authors did find that surgery for the removal of one breast was associated with a higher risk of death than the other options examined in the study. Continue reading

Increase seen in use of double mastectomy, although not associated with reduced death

Increase seen in use of double mastectomy, although not associated with reduced death

Among women diagnosed with early-stage breast cancer in California, the percentage undergoing a double mastectomy increased substantially between 1998 and 2011, although this procedure was not associated with a lower risk of death than breast-conserving surgery plus radiation, according to a study in the September 3 issue of JAMA . The authors did find that surgery for the removal of one breast was associated with a higher risk of death than the other options examined in the study. Randomized trials have demonstrated similar survival for patients with early-stage breast cancer treated with breast-conserving surgery and radiation or with mastectomy. Continue reading

Comparison of named diet programs finds little difference in weight loss outcomes

Comparison of named diet programs finds little difference in weight loss outcomes

In an analysis of data from nearly 50 trials including about 7,300 individuals, significant weight loss was observed with any low-carbohydrate or low-fat diet, with weight loss differences between diet programs small, findings that support the practice of recommending any diet that a patient will adhere to in order to lose weight, according to a study in the September 3 issue of JAMA . Named or branded (trade-marked) weight loss programs provide structured dietary and lifestyle recommendations via popular books and in-person or online behavioral support and represent a multibillion dollar industry. Debate regarding the relative merit of the diets is accompanied by advertising claiming which macronutrient composition is superior, such as a low-carbohydrate or low-fat diet. Continue reading

Comparison of named diet programs finds little difference in weight loss outcomes

Comparison of named diet programs finds little difference in weight loss outcomes

In an analysis of data from nearly 50 trials including about 7,300 individuals, significant weight loss was observed with any low-carbohydrate or low-fat diet, with weight loss differences between diet programs small, findings that support the practice of recommending any diet that a patient will adhere to in order to lose weight, according to a study in the September 3 issue of JAMA . Continue reading

Experts denounce clinical trials of unscientific, ‘alternative’ medicines

Experts denounce clinical trials of unscientific, ‘alternative’ medicines

Experts writing in the Cell Press journal Trends in Molecular Medicine on August 20th call for an end to clinical trials of “highly implausible treatments” such as homeopathy and reiki. Continue reading

‘Treatments waiting to be discovered’ inside new database

‘Treatments waiting to be discovered’ inside new database

Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to disease. Or what gene is regulated by a microRNA found in sick patients Continue reading

Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA , a theme issue on HIV/AIDS. Patients infected with HIV demonstrate a high prevalence of nonalcoholic fatty liver disease, estimated at 30 percent to 40 percent Continue reading

Combination treatment for hep C associated with favorable response among HIV patients

Combination treatment for hep C associated with favorable response among HIV patients

HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA , a theme issue on HIV/AIDS. The issue is being released early to coincide with the International AIDS Conference Continue reading