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Tag Archives: biology

Diagnostic criteria for Christianson Syndrome

Diagnostic criteria for Christianson Syndrome

Because the severe autism-like condition Christianson Syndrome was only first reported in 1999 and some symptoms take more than a decade to appear, families and doctors urgently need fundamental information about it. Continue reading

Genetic cause of common breast tumors found

Genetic cause of common breast tumors found

A multi-disciplinary team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital have made a major breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumors diagnosed in women. Continue reading

Metabolic enzyme stops progression of most common type of kidney cancer

Metabolic enzyme stops progression of most common type of kidney cancer

In an analysis of small molecules called metabolites used by the body to make fuel in normal and cancerous cells in human kidney tissue, a research team from the Perelman School of Medicine at the University of Pennsylvania identified an enzyme key to applying the brakes on tumor growth. Continue reading

New clues to brain’s wiring found by scientists

New clues to brain’s wiring found by scientists

New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. Continue reading

Immune cell’s role in intestinal movement may lead to better understanding of irritable bowel syndrome

Immune cell’s role in intestinal movement may lead to better understanding of irritable bowel syndrome

Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS). Researchers from Penn State College of Medicine, in collaboration with other scientists, have reported the role of macrophages in regulating the contractions of the colon to push digested material through the digestive tract. The muscular lining of the intestine contains a distinct kind of macrophage, an immune system cell that helps fight infections Continue reading

Genetic variations may modify cardiovascular benefit of aspirin

Genetic variations may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease. Now, a new study suggests that common genetic variation in the gene for catechol-O-methyltransferase (COMT) may modify the cardiovascular benefit of aspirin, and in some people, may confer slight harm Continue reading

Eradicating fatal sleeping sickness by killing off the tsetse fly

Eradicating fatal sleeping sickness by killing off the tsetse fly

A BYU ecologist is playing a role in the effort to curb a deadly disease affecting developing nations across equatorial Africa. Steven L Continue reading

Effects of starvation can be passed to future generations, through small RNAs apparently without DNA involvement

Effects of starvation can be passed to future generations, through small RNAs apparently without DNA involvement

Evidence from human famines and animal studies suggests that starvation can affect the health of descendants of famished individuals. But how such an acquired trait might be transmitted from one generation to the next has not been clear Continue reading

Drug’s effect on Alzheimer’s may depend on severity of disease

Drug’s effect on Alzheimer’s may depend on severity of disease

A cancer drug that has shown promise against Alzheimer’s disease (AD) in mice and has begun early clinical trials has yielded perplexing results in a novel mouse model of AD that mimics the genetics and pathology of the human disease more closely than any other animal model. The drug, bexarotene, was found to reduce levels of the neurotoxic protein amyloid-beta in experimental mice with late-stage Alzheimer’s but to increase levels during early stages of disease. The finding, by researchers at the University of Illinois at Chicago College of Medicine, was reported July 16 at the Alzheimer’s Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the human disease. Continue reading

Immune response to infectious disease: New findings on properdin

Immune response to infectious disease: New findings on properdin

University of Leicester researchers — including three PhD graduates — contribute significantly to knowledge in immunology University of Leicester researchers have released evidence substantiating an unexpected dual role of an important component of the immune system. Findings by researchers at the University’s Department of Infection, Immunity and Inflammation — including three PhD graduates — are published in a paper for the journal ‘Medical Microbiology and Immunology’ Continue reading