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Tag Archives: Body

Surprising discovery: HIV hides in gut, evading eradication

Surprising discovery: HIV hides in gut, evading eradication

Researchers at UC Davis have made some surprising discoveries about the body’s initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β). Continue reading

From bite site to brain: How rabies virus hijacks and speeds up transport in nerve cells

From bite site to brain: How rabies virus hijacks and speeds up transport in nerve cells

Rabies (and rabies virus, its causative agent) is usually transmitted through the bite of an infected animal into muscle tissue of the new host. From there, the virus travels all the way to the brain where it multiplies and causes the usually fatal disease. Continue reading

Dosage of HIV drug may be ineffective for half of African-Americans

Dosage of HIV drug may be ineffective for half of African-Americans

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. Continue reading

Tissue regeneration using anti-inflammatory nanomolecules

Tissue regeneration using anti-inflammatory nanomolecules

Date: August 22, 2014 Source: Children’s Memorial Hospital Summary: Anyone who has suffered an injury can probably remember the after-effects, including pain, swelling or redness. These are signs that the body is fighting back against the injury. When tissue in the body is damaged, biological programs are activated to aid in tissue regeneration Continue reading

Missing Protein Restored in Patients with Muscular Dystrophy

Missing Protein Restored in Patients with Muscular Dystrophy

When muscle cell membranes are damaged, the repair protein dysferlin is activated and reseals muscle membrane tears. If this repair protein is altered due to a genetic mutation, the body’s own “quality control” system (the so called proteasome) identifies the protein as being defective and eliminates it. Continue reading

New technology offers insight into cholesterol

New technology offers insight into cholesterol

With new advanced techniques developed by the Copenhagen Center for Glycomics at the University of Copenhagen it is possible to study cells in greater detail than ever before. The findings have just been published in the Journal of Biological Chemistry and may, in the long term, improve the treatment of high cholesterol Continue reading

Cell discovery brings blood disorder cure closer

Cell discovery brings blood disorder cure closer

A cure for a range of blood disorders and immune diseases is in sight, according to scientists who have unravelled the mystery of stem cell generation. Continue reading

‘Worm pill’ could ease autoimmune disease symptoms

‘Worm pill’ could ease autoimmune disease symptoms

Experts believe a molecule in parasitic worms could help explain why worm infections can effectively treat a range of autoimmune diseases, including multiple sclerosis, psoriasis, rheumatoid arthritis and lupus. The Monash University study, published in the FASEB Journal , successfully identified peptides from parasitic worms that suppress the body’s immune response. Researchers believe this could pave the way for a new drug containing the peptide to provide relief from the symptoms of autoimmune diseases. Continue reading

On the frontiers of cyborg science: Development of electronic-brain relationship

On the frontiers of cyborg science: Development of electronic-brain relationship

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. Now taking this human-machine concept to an unprecedented level, pioneering scientists are working on the seamless marriage between electronics and brain signaling with the potential to transform our understanding of how the brain works — and how to treat its most devastating diseases. Their presentation is taking place at the 248th National Meeting & Exposition of the American Chemical Society (ACS), the world’s largest scientific society. Continue reading

Cell signaling pathway linked to obesity, type 2 diabetes

Cell signaling pathway linked to obesity, type 2 diabetes

A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment. A research team led by Shihuan Kuang, associate professor of animal sciences, found that blocking Notch signaling in the fat tissue of mice caused white fat cells to transform into a “leaner” type of fat known as beige fat. Continue reading