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Tag Archives: Brain

Novel compound halts cocaine addiction, relapse behaviors

Novel compound halts cocaine addiction, relapse behaviors

A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found. Continue reading

Hundreds of genetic mutations found in healthy blood of a supercentenarian

Hundreds of genetic mutations found in healthy blood of a supercentenarian

Genetic mutations are commonly studied because of links to diseases such as cancer; however, little is known about mutations occurring in healthy individuals. In a study published online in Genome Research , researchers detected over 400 mutations in healthy blood cells of a 115-year-old woman, suggesting that lesions at these sites are largely harmless over the course of a lifetime. Our blood is continually replenished by hematopoietic stem cells that reside in the bone marrow and divide to generate different types of blood cells, including white blood cells Continue reading

Airport security-style technology could help doctors decide on stroke treatment

Airport security-style technology could help doctors decide on stroke treatment

A new computer program could help doctors predict which patients might suffer potentially fatal side-effects from a key stroke treatment. The program, which assesses brain scans using pattern recognition software similar to that used in airport security and passport control, has been developed by researchers at Imperial College London. Results of a pilot study funded by the Wellcome Trust, which used the software are published in the journal Neuroimage Clinical Continue reading

Novel function of protein linked to Alzheimer’s disease discovered

Novel function of protein linked to Alzheimer’s disease discovered

A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer’s disease. This discovery may help researchers understand how the protein goes awry in the brains of Alzheimer’s disease patients, and potentially paves the way for the development of innovative therapeutics to improve the brain function of dementia patients. The findings were published in the scientific research journal Nature Communications last month Continue reading

Finding turns neuroanatomy on its head: Researchers present new view of myelin

Finding turns neuroanatomy on its head: Researchers present new view of myelin

Harvard neuroscientists have made a discovery that turns 160 years of neuroanatomy on its head. Myelin, the electrical insulating material long known to be essential for the fast transmission of impulses along the axons of nerve cells, is not as ubiquitous as thought, according to a new work lead by Professor Paola Arlotta of the Harvard Stem Cell Institute (HSCI) and the University’s Department of Stem Cell and Regenerative Biology, in collaboration with Professor Jeff Lichtman, of Harvard’s Department of Molecular and Cellular Biology. “Myelin is a relatively recent invention during evolution,” says Arlotta. Continue reading

Finding turns neuroanatomy on its head: Researchers present new view of myelin

Finding turns neuroanatomy on its head: Researchers present new view of myelin

Harvard neuroscientists have made a discovery that turns 160 years of neuroanatomy on its head. Myelin, the electrical insulating material long known to be essential for the fast transmission of impulses along the axons of nerve cells, is not as ubiquitous as thought, according to a new work lead by Professor Paola Arlotta of the Harvard Stem Cell Institute (HSCI) and the University’s Department of Stem Cell and Regenerative Biology, in collaboration with Professor Jeff Lichtman, of Harvard’s Department of Molecular and Cellular Biology. “Myelin is a relatively recent invention during evolution,” says Arlotta. Continue reading

‘Brain training’ overcomes tics in Tourette syndrome, study finds

‘Brain training’ overcomes tics in Tourette syndrome, study finds

Teenagers diagnosed with Tourette Syndrome (TS) were slower than their typically developing peers when asked to perform a task that involved them simply moving their eyes to look at targets. However, they significantly outperformed their peers when the task was more demanding and required them to choose between looking at or away from targets. Continue reading

How kids’ brain structures grow as memory develops

How kids’ brain structures grow as memory develops

Our ability to store memories improves during childhood, associated with structural changes in the hippocampus and its connections with prefrontal and parietal cortices. New research from UC Davis is exploring how these brain regions develop at this crucial time Continue reading

Eavesdropping on brain cell chatter

Eavesdropping on brain cell chatter

Everything we do — all of our movements, thoughts and feelings — are the result of neurons talking with one another, and recent studies have suggested that some of the conversations might not be all that private. Brain cells known as astrocytes may be listening in on, or even participating in, some of those discussions. But a new mouse study suggests that astrocytes might only be tuning in part of the time — specifically, when the neurons get really excited about something. Continue reading

Cancer drugs block dementia-linked brain inflammation, study finds

Cancer drugs block dementia-linked brain inflammation, study finds

A class of drugs developed to treat immune-related conditions and cancer — including one currently in clinical trials for glioblastoma and other tumors — eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers. In their study, assistant professor of neurobiology & behavior Kim Green and colleagues discovered that the drugs, which can be delivered orally, eradicated microglia, the primary immune cells of the brain. These cells exacerbate many neural diseases, including Alzheimer’s and Parkinson’s, as well as brain injury Continue reading