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Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Understanding drinking behaviors among women with unwanted pregnancies

Understanding drinking behaviors among women with unwanted pregnancies

Most women reduce or stop drinking alcohol upon discovery of pregnancy. However, little information exists about changes in alcohol use, and factors contributing to these changes, among women with unwanted pregnancies Continue reading

Understanding drinking behaviors among women with unwanted pregnancies

Understanding drinking behaviors among women with unwanted pregnancies

Most women reduce or stop drinking alcohol upon discovery of pregnancy. However, little information exists about changes in alcohol use, and factors contributing to these changes, among women with unwanted pregnancies Continue reading

Genome editing technique advanced by researchers

Genome editing technique advanced by researchers

Customized genome editing — the ability to edit desired DNA sequences to add, delete, activate or suppress specific genes — has major potential for application in medicine, biotechnology, food and agriculture. Now, in a paper published in Molecular Cell , North Carolina State University researchers and colleagues examine six key molecular elements that help drive this genome editing system, which is known as CRISPR-Cas. NC State’s Dr. Continue reading

Mutation associated with cleft palate in humans, dogs identified

Mutation associated with cleft palate in humans, dogs identified

Scientists studying birth defects in humans and purebred dogs have identified an association between cleft lip and cleft palate — conditions that occur when the lip and mouth fail to form properly during pregnancy — and a mutation in the ADAMTS20 gene. Continue reading

New front in war on Alzheimer’s, other protein-linked brain diseases

New front in war on Alzheimer’s, other protein-linked brain diseases

A surprise discovery that overturns decades of thinking about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent diseases such as Alzheimer’s and Parkinson’s, which have been linked to the accumulation of improperly folded proteins in the brain. “This finding provides a whole other outlook on protein-folding diseases; a new way to go after them,” said Andrew Dillin, the Thomas and Stacey Siebel Distinguished Chair of Stem Cell Research in the Department of Molecular and Cell Biology and Howard Hughes Medical Institute investigator at the University of California, Berkeley. Dillin, UC Berkeley postdoctoral fellows Nathan A Continue reading

Drug used for another disease slows progression of Parkinson’s

Drug used for another disease slows progression of Parkinson’s

A new study from UCLA found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson’s disease in mice. Continue reading

Drug used for another disease slows progression of Parkinson’s

Drug used for another disease slows progression of Parkinson’s

A new study from UCLA found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson’s disease in mice. The study, published in the October edition of the journal Neurotherapeutics , found that the drug, AT2101, which has also been studied for Gaucher disease, improved motor function, stopped inflammation in the brain and reduced levels of alpha-synuclein, a protein critically involved in Parkinson’s. though the exact cause of Parkinson’s is unknown, evidence points to an accumulation of alpha-synuclein, which has been found to be common to all people with the disorder Continue reading

Sesame Street goes to jail: Physicians should follow

Sesame Street goes to jail: Physicians should follow

More than two million people are incarcerated in the United States, the highest incarceration rate in the world. So perhaps it comes as no surprise that last year the popular children’s television series Sesame Street introduced a character that has an incarcerated father. Continue reading