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Tag Archives: Cell

Cells put off protein production during times of stress

Cells put off protein production during times of stress

Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed cell can end up producing misshapen proteins that are unfolded or misfolded. Now Duke University researchers in North Carolina and Singapore have shown that the cell recognizes the buildup of these misfolded proteins and responds by reshuffling its workload, much like a stressed out employee might temporarily move papers from an overflowing inbox into a junk drawer. Continue reading

Cells put off protein production during times of stress

Cells put off protein production during times of stress

Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed cell can end up producing misshapen proteins that are unfolded or misfolded. Now Duke University researchers in North Carolina and Singapore have shown that the cell recognizes the buildup of these misfolded proteins and responds by reshuffling its workload, much like a stressed out employee might temporarily move papers from an overflowing inbox into a junk drawer Continue reading

Ultraviolet light-induced mutation drives many skin cancers, researchers find

Ultraviolet light-induced mutation drives many skin cancers, researchers find

A genetic mutation caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to researchers at the Stanford University School of Medicine. Continue reading

Banked blood grows stiffer with age, study finds

Banked blood grows stiffer with age, study finds

It may look like fresh blood and flow like fresh blood, but the longer blood is stored, the less it can carry oxygen into the tiny microcapillaries of the body, says a new study from University of Illinois researchers. Using advanced optical techniques, the researchers measured the stiffness of the membrane surrounding red blood cells over time Continue reading

Knowing how bacteria take out trash could lead to new antibiotics

Knowing how bacteria take out trash could lead to new antibiotics

A collaborative team of scientists including biochemist Peter Chien at the University of Massachusetts Amherst has reconstructed how bacteria tightly control their growth and division, a process known as the cell cycle, by specifically destroying key proteins through regulated protein degradation. Regulated protein degradation uses specific enzymes called energy dependent proteases to selective destroy certain targets. Because regulated protein degradation is critical for bacterial virulence and invasion, understanding how these proteases function should help to uncover pathways that can be targeted by new antibiotics Continue reading

Elusive viral ‘machine’ architecture finally rendered

Elusive viral ‘machine’ architecture finally rendered

For half a century biologists have studied the way that the lambda virus parks DNA in the chromosome of a host E. coli bacterium and later extracts it as a model reaction of genetic recombination. Continue reading

Hybrid-motor helps cells push their way through tissues

Hybrid-motor helps cells push their way through tissues

Research has uncovered how two cellular motors, previously thought to compete with each other, can actually work together to help cells squeezing through a crowded mass of cells. Continue reading

Nanoparticles used to enhance chemotherapy

Nanoparticles used to enhance chemotherapy

University of Georgia researchers have developed a new formulation of cisplatin, a common chemotherapy drug, that significantly increases the drug’s ability to target and destroy cancerous cells. Continue reading

Role of cohesin in cancer revised by researcher

Role of cohesin in cancer revised by researcher

Massive sequencing of cancer genomes brings to light new genes every day that could be involved in the process of tumour formation. Continue reading

Gene in brain linked to kidney cancer, researchers say

Gene in brain linked to kidney cancer, researchers say

A gene known to control brain growth and development is heavily involved in promoting clear cell renal cell carcinoma, the most common form of kidney cancer, researchers from Mayo Clinic in Florida are reporting. Continue reading