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Tag Archives: Chicago

Drug’s effect on Alzheimer’s may depend on severity of disease

Drug’s effect on Alzheimer’s may depend on severity of disease

A cancer drug that has shown promise against Alzheimer’s disease (AD) in mice and has begun early clinical trials has yielded perplexing results in a novel mouse model of AD that mimics the genetics and pathology of the human disease more closely than any other animal model. The drug, bexarotene, was found to reduce levels of the neurotoxic protein amyloid-beta in experimental mice with late-stage Alzheimer’s but to increase levels during early stages of disease. The finding, by researchers at the University of Illinois at Chicago College of Medicine, was reported July 16 at the Alzheimer’s Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the human disease. Continue reading

Young Hispanics often obese, at higher risk for heart diseases

Young Hispanics often obese, at higher risk for heart diseases

Obesity is common among U.S. Hispanics and is severe particularly among young Hispanics, according to research in the Journal of the American Heart Association ( JAHA ). Continue reading

Doctors have ethical obligation to educate, protect athletes from concussion, experts say

Doctors have ethical obligation to educate, protect athletes from concussion, experts say

The American Academy of Neurology (AAN), the largest professional association of neurologists and a leading authority on sports concussion, is releasing a new position paper that states doctors have an ethical obligation to educate and protect athletes from sports concussion and clear them to play only when the athlete is medically ready, standing firm against objections from players, parents or coaches. The statement is published in the July 9, 2014, online issue of Neurology ®, the medical journal of the AAN, and is being released ahead of The Sports Concussion Conference, July 11-13, 2014, in Chicago, where the AAN will share the latest scientific advances in diagnosing and treating sports concussion. The AAN position statement calls for doctors to safeguard the future mental and physical health of athletes as a top priority, especially regarding return-to-play decision-making. Continue reading

How keeping cool could spur metabolic benefits

How keeping cool could spur metabolic benefits

A new study being presented today at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago, demonstrates that ambient temperatures can influence the growth or loss of brown fat in people. Cool environments stimulate growth, warm environments loss. Brown fat, also known as brown adipose tissue, is a special kind of fat that burns energy to generate heat Continue reading

How keeping cool could spur metabolic benefits

How keeping cool could spur metabolic benefits

A new study being presented today at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago, demonstrates that ambient temperatures can influence the growth or loss of brown fat in people. Cool environments stimulate growth, warm environments loss. Brown fat, also known as brown adipose tissue, is a special kind of fat that burns energy to generate heat Continue reading

Molecule regulates production of antibacterial agent used by immune cells

Molecule regulates production of antibacterial agent used by immune cells

Researchers have discovered how a protein molecule in immune cells promotes the production of nitric oxide, a potent weapon in the cells’ arsenal to defend the body from bacterial attack. The protein may offer a target for reining in the inflammatory response, which must be able to fight infection without damaging tissue Continue reading

Bloodstream infections reduced through better central line care at three hospitals

Bloodstream infections reduced through better central line care at three hospitals

Whether through the use of alcohol-containing caps or basic cleaning of the injection port of the central line, infection preventionists at three hospitals are finding successful ways to stop germs from entering central line catheters and causing bloodstream infections in patients. A trio of abstracts, to be presented on June 7 at the 41st Annual Conference of the Association for Professionals in Infection Control and Epidemiology (APIC), addresses the challenge of keeping bacteria from entering the bloodstream through a central line, a catheter placed in a large vein to deliver medicine and fluids during hospitalization. Patients in intensive care units (ICUs) may need to have their lines accessed 20 or more times per day, increasing the risk for infection and contamination Continue reading

Early palliative support services help those caring for patients with advanced cancer

Early palliative support services help those caring for patients with advanced cancer

Dartmouth researchers have found that those caring for patients with advanced cancer experienced reduced depression and felt less burdened by caregiving tasks when palliative support services were offered soon after the patient’s diagnosis. They presented their findings at the American Society of Clinical Oncologist (ASCO) annual meeting in Chicago on June 3, 2014. “Family caregivers are a crucial part of the patient care team. Continue reading

Patients with metastatic colon cancer respond to new combination therapy

Patients with metastatic colon cancer respond to new combination therapy

In an aggressive disease known for poor response rates, researchers from The University of Texas MD Anderson Cancer Center found patients with advanced colorectal cancer responded well to a combination therapy of the drugs vermurafenib, cetuximab and irinotecan. Continue reading

Patients with metastatic colon cancer respond to new combination therapy

Patients with metastatic colon cancer respond to new combination therapy

In an aggressive disease known for poor response rates, researchers from The University of Texas MD Anderson Cancer Center found patients with advanced colorectal cancer responded well to a combination therapy of the drugs vermurafenib, cetuximab and irinotecan. Continue reading