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Tag Archives: collaborators

The long and the short of telomeres: Loneliness impacts DNA repair, parrot study shows

The long and the short of telomeres: Loneliness impacts DNA repair, parrot study shows

Scientists at the Vetmeduni Vienna examined the telomere length of captive African grey parrots. They found that the telomere lengths of single parrots were shorter than those housed with a companion parrot, which supports the hypothesis that social stress can interfere with cellular aging and a particular type of DNA repair Continue reading

Bacterial gut biome may guide colon cancer progression

Bacterial gut biome may guide colon cancer progression

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, researchers from The Wistar Institute will present findings that suggest the colon “microbiome” of gut bacteria can change the tumor microenvironment in a way that promotes the growth and spread of tumors. Their results suggest that bacterial virulence proteins may suppress DNA repair proteins within the epithelial cells that line the colon. Continue reading

New class of malaria drugs using essential calcium enzyme developed

New class of malaria drugs using essential calcium enzyme developed

Dec. 27, 2012 — Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, AIDS, Alzheimer’s disease, multiple sclerosis, and cancer Continue reading

Body language, not facial expressions, broadcasts what’s happening to us

Body language, not facial expressions, broadcasts what’s happening to us

ScienceDaily (Nov. 29, 2012) — If you think that you can judge by examining someone’s facial expressions if he has just hit the jackpot in the lottery or lost everything in the stock market — think again. Continue reading

Harnessing anticancer drugs for the future fight against influenza

Harnessing anticancer drugs for the future fight against influenza

ScienceDaily (Sep. 5, 2012) — Researchers at the Institute for Molecular Medicine Finland (FIMM) together with their collaborators have developed a new cell screening method that can be used to identify potential anti-influenza drugs Continue reading

New compounds inhibit prion infection

New compounds inhibit prion infection

ScienceDaily (July 23, 2012) — A team of University of Alberta researchers has identified a new class of compounds that inhibit the spread of prions, misfolded proteins in the brain that trigger lethal neurodegenerative diseases in humans and animals. U of A chemistry researcher Frederick West and his team have developed compounds that clear prions from infected cells derived from the brain. Continue reading

Better treatment for brain cancer revealed by new molecular insights

Better treatment for brain cancer revealed by new molecular insights

ScienceDaily (July 9, 2012) — Nearly a third of adults with the most common type of brain cancer develop recurrent, invasive tumors after being treated with a drug called bevacizumab. Continue reading

Study: No-fat, low-fat dressings don’t get most nutrients out of salads

Study: No-fat, low-fat dressings don’t get most nutrients out of salads

ScienceDaily (June 19, 2012) — The vegetables in salads are chock-full of important vitamins and nutrients, but you won’t get much benefit without the right type and amount of salad dressing, a Purdue University study shows. In a human trial, researchers fed subjects salads topped off with saturated, monounsaturated and polyunsaturated fat-based dressings and tested their blood for absorption of fat-soluble carotenoids — compounds such as lutein, lycopene, beta-carotene and zeaxanthin. Those carotenoids are associated with reduced risk of several chronic and degenerative diseases such as cancer, cardiovascular disease and macular degeneration Continue reading

Study: No-fat, low-fat dressings don’t get most nutrients out of salads

Study: No-fat, low-fat dressings don’t get most nutrients out of salads

ScienceDaily (June 19, 2012) — The vegetables in salads are chock-full of important vitamins and nutrients, but you won’t get much benefit without the right type and amount of salad dressing, a Purdue University study shows. In a human trial, researchers fed subjects salads topped off with saturated, monounsaturated and polyunsaturated fat-based dressings and tested their blood for absorption of fat-soluble carotenoids — compounds such as lutein, lycopene, beta-carotene and zeaxanthin Continue reading

New technique generates predictable complex, wavy shapes: May explain brain folds and be useful for drug delivery

New technique generates predictable complex, wavy shapes: May explain brain folds and be useful for drug delivery

ScienceDaily (May 3, 2012) — The flexible properties of hydrogels — highly absorbent, gelatinous polymers that shrink and expand depending on environmental conditions such as humidity, pH and temperature — have made them ideal for applications from contact lenses to baby diapers and adhesives. In recent years, researchers have investigated hydrogels’ potential in drug delivery, engineering them into drug-carrying vehicles that rupture when exposed to certain environmental stimuli. Continue reading