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Researcher develops, proves effectiveness of new drug for spinal muscular atrophy

Researcher develops, proves effectiveness of new drug for spinal muscular atrophy

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time. Continue reading

Researcher develops, proves effectiveness of new drug for spinal muscular atrophy

Researcher develops, proves effectiveness of new drug for spinal muscular atrophy

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time. Now, researchers at the University of Missouri have made a recent breakthrough with the development of a new compound found to be highly effective in animal models of the disease Continue reading

Certain form of baldness at age 45 linked to higher risk for aggressive prostate cancer

Certain form of baldness at age 45 linked to higher risk for aggressive prostate cancer

A new, large cohort analysis from the prospective Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, indicates that men who had moderate baldness affecting both the front and the crown of their head at age 45 were at a 40% increased risk of developing aggressive prostate cancer (usually indicates a faster growing tumor resulting in poorer prognosis relative to non-aggressive prostate cancer) later in life, compared to men with no baldness. Continue reading

Certain form of baldness at age 45 linked to higher risk for aggressive prostate cancer

Certain form of baldness at age 45 linked to higher risk for aggressive prostate cancer

A new, large cohort analysis from the prospective Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, indicates that men who had moderate baldness affecting both the front and the crown of their head at age 45 were at a 40% increased risk of developing aggressive prostate cancer (usually indicates a faster growing tumor resulting in poorer prognosis relative to non-aggressive prostate cancer) later in life, compared to men with no baldness. Continue reading

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches. They published their results this month in Cell Reports . Continue reading

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches. They published their results this month in Cell Reports . Continue reading

New genetic targets discovered in fight against muscle-wasting disease

New genetic targets discovered in fight against muscle-wasting disease

Scientists have pinpointed for the first time the genetic cause in some people of an incurable muscle-wasting disease, Emery-Dreifuss muscular dystrophy (EDMD). The international research team led by the University of Leicester say the finding of two target genes opens the possibility of developing drugs to tackle the disease in these patients Continue reading

Statins may protect against microvascular complications of diabetes

Statins may protect against microvascular complications of diabetes

The development of common diabetes complications that can lead to blindness and amputations could be reduced by taking statins, indicates new research published in The Lancet Diabetes & Endocrinology. It is well established that statins via cholesterol lowering effectively reduce the risks of heart attack and stroke in people with type 2 diabetes, but whether statin use affects the development of small blood vessel (or microvascular) complications, such as eye, nerve, and kidney disease in individuals with diabetes is not known. “Since high levels of blood glucose, the hallmark of diabetes, are linked with microvascular disease, and since statins are suspected of raising glucose levels, we tested the hypothesis that individuals taking a statin before a diagnosis of diabetes might be at increased risk of developing microvascular complications,” explains study author Professor Børge G Nordestgaard, Chief Physician in Clinical Biochemistry at Copenhagen University Hospital in Denmark. Continue reading

Ultraviolet light-induced mutation drives many skin cancers, researchers find

Ultraviolet light-induced mutation drives many skin cancers, researchers find

A genetic mutation caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to researchers at the Stanford University School of Medicine. Continue reading

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

In most of the tissues of the body, specialized immune cells are entrusted with the task of engulfing the billions of dead cells that are generated every day. When these garbage disposals don’t do their job, dead cells and their waste products rapidly pile up, destroying healthy tissue and leading to autoimmune diseases such as lupus and rheumatoid arthritis. Continue reading