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Tag Archives: Development

Disease decoded: Gene mutation may lead to development of new cancer drugs

Disease decoded: Gene mutation may lead to development of new cancer drugs

The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly. Scientists at the University of Michigan and the U-M Health System recently discovered a protein mutation that causes the devastating disease dyskeratosis congenita, in which precious hematopoietic stem cells can’t regenerate and make new blood Continue reading

Investigating ‘underground’ habitat of Listeria bacteria

Investigating ‘underground’ habitat of Listeria bacteria

The literature describes Listeria as ubiquitous bacteria with widespread occurrence. Yet they only become a problem for humans and animals when they contaminate food processing facilities, multiply, and enter the food chain in high concentrations. An infection with Listeria monocytogenes can even be fatal for humans or animals with weakened immune systems. Continue reading

New tool assesses skill development in robotic microsurgery

New tool assesses skill development in robotic microsurgery

A new standardized assessment provides a useful tool for tracking surgeons’ progress as they develop the skills needed to perform robot-assisted microsurgery, reports a study in the October issue of Plastic and Reconstructive Surgery® , the official medical journal of the American Society of Plastic Surgeons (ASPS). “The Structured Assessment of Robotic Microsurgical Skills (SARMS) is the first validated instrument for assessing robotic microsurgical skills,” according to the report by ASPS Member Surgeon Dr Jesse C Continue reading

Scanning babies’ fingerprints could save lives through vaccination tracking

Scanning babies’ fingerprints could save lives through vaccination tracking

Each year 2.5 million children die worldwide because they do not receive life-saving vaccinations at the appropriate time. Anil Jain, Michigan State University professor, is developing a fingerprint-based recognition method to track vaccination schedules for infants and toddlers, which will increase immunization coverage and save lives Continue reading

Researchers engineer ‘Cas9′ animal models to study disease, inform drug discovery

Researchers engineer ‘Cas9′ animal models to study disease, inform drug discovery

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new “Cas9 mouse” model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers. Continue reading

Brain chemical potential new hope in controlling Tourette Syndrome tics

Brain chemical potential new hope in controlling Tourette Syndrome tics

A chemical in the brain plays a vital role in controlling the involuntary movements and vocal tics associated with Tourette Syndrome (TS), a new study has shown. Continue reading

New protein players found in key disease-related metabolic pathway

New protein players found in key disease-related metabolic pathway

To coordinate their size and growth with current environmental conditions, cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway, which senses cellular stresses, growth factors, and the availability of nutrients, such as amino acids and glucose. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends. Continue reading