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Tag Archives: Diseases

Defective gene renders diarrhea vaccine ineffective

Defective gene renders diarrhea vaccine ineffective

Acute diarrheal illnesses cause nearly one-fifth of all child deaths in developing countries. The most common cause is rotavirus. Continue reading

Oral capsule as effective as invasive procedures for delivery of fecal transplant

Oral capsule as effective as invasive procedures for delivery of fecal transplant

A noninvasive method of delivering a promising therapy for persistent Clostridium difficile ( C. difficile ) infection appears to be as effective as treatment via colonoscopy or through a nasogastric tube Continue reading

Pneumococcal vaccine reduces antibiotic-resistant infections in children by 62 percent

Pneumococcal vaccine reduces antibiotic-resistant infections in children by 62 percent

The pneumococcal vaccine recommended for young children not only prevents illness and death, but also has dramatically reduced severe antibiotic-resistant infections, suggests nationwide research being presented at IDWeek 2014™. Continue reading

College athletes in contact sports more likely to carry MRSA, study finds

College athletes in contact sports more likely to carry MRSA, study finds

Even if they don’t show signs of infection, college athletes who play football, soccer and other contact sports are more likely to carry the superbug methicillin-resistant Staphylococcus aureus (MRSA), suggests a study on MRSA and athletes, which is being presented at IDWeek 2014™. This puts them at higher risk for infection and increases the likelihood of spreading the bug, which can cause serious and even fatal infections. The study is the first to observe college athletes who are not part of a larger MRSA outbreak Continue reading

Surprising diversity of antibody family provides clues for HIV vaccine design

Surprising diversity of antibody family provides clues for HIV vaccine design

Scientists at The Scripps Research Institute (TSRI) have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine. “In a sense, this antibody family takes more than one shot on goal in order to hit divergent forms of HIV,” said Ian A. Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends Continue reading

Discovery may lead to better treatments for autoimmune diseases, bone loss

Discovery may lead to better treatments for autoimmune diseases, bone loss

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. Researchers at Washington University School of Medicine in St. Louis redesigned a molecule that controls immune cell activity, changing the molecule’s target and altering the effects of the signal it sends. Continue reading

Chemists recruit anthrax to deliver cancer drugs

Chemists recruit anthrax to deliver cancer drugs

Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. Continue reading

Chemists recruit anthrax to deliver cancer drugs

Chemists recruit anthrax to deliver cancer drugs

Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs. “Anthrax toxin is a professional at delivering large enzymes into cells,” says Bradley Pentelute, the Pfizer-Laubauch Career Development Assistant Professor of Chemistry at MIT. Continue reading

Premature deaths could be reduced by 40% over next 20 years, researchers say

Premature deaths could be reduced by 40% over next 20 years, researchers say

New research published today in The Lancet suggests that, with sustained international efforts, the number of premature deaths could be reduced by 40% over the next two decades (2010-2030), halving under-50 mortality and preventing a third of the deaths at ages 50-69 years. The findings reveal that, between 2000 and 2010, child deaths fell by one-third worldwide, helped by the fourth Millennium Development Goal (MDG) to reduce child deaths by two-thirds; and premature deaths among adults fell by one-sixth, helped by MDG 5 to reduce maternal mortality and MDG 6 to fight AIDS, malaria and other diseases. Continue reading