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Tag Archives: Diseases

Biologists delay the aging process by ‘remote control’

Biologists delay the aging process by ‘remote control’

UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems. Working with fruit flies, the life scientists activated a gene called AMPK that is a key energy sensor in cells; it gets activated when cellular energy levels are low Continue reading

Researchers discover key to making new muscles

Researchers discover key to making new muscles

Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have developed a novel technique to promote tissue repair in damaged muscles. Continue reading

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

In most of the tissues of the body, specialized immune cells are entrusted with the task of engulfing the billions of dead cells that are generated every day. When these garbage disposals don’t do their job, dead cells and their waste products rapidly pile up, destroying healthy tissue and leading to autoimmune diseases such as lupus and rheumatoid arthritis. Continue reading

New enzyme targets for selective cancer therapies

New enzyme targets for selective cancer therapies

Thanks to important discoveries in basic and clinical research and technological advances, the fight against cancer has mobilized into a complex offensive spanning multiple fronts. Work happening in a University of Alberta chemistry lab could help find new and more selective therapies for cancer. Researchers have developed a compound that targets a specific enzyme overexpressed in certain cancers — and they have tested its activity in cells from brain tumours Continue reading

Contrary to popular belief, more exercise is not always better

Contrary to popular belief, more exercise is not always better

There is strong epidemiological evidence of the importance of regular physical activity, such as brisk walking and jogging, in the management and rehabilitation of cardiovascular disease and in lowering the risk of death from other diseases such as hypertension, stroke, and type 2 diabetes. The Physical Activity Guidelines for Americans recommends about 150 minutes per week of moderate-intensity exercise or about 75 minutes of vigorous-intensity exercise. But there is clear evidence of an increase in cardiovascular deaths in heart attack survivors who exercise to excess, according to a new study published in Mayo Clinic Proceedings Continue reading

Stress during pregnancy can be passed down through generations, rat study shows

Stress during pregnancy can be passed down through generations, rat study shows

To better understand problems during pregnancies today, we should look to the experiences of our ancestors, research published in the open access journal BMC Medicine suggests. Scientists investigating pregnancies in four generations of rats show that inherited epigenetic effects of stress could affect pregnancies for generations. Continue reading

‘Treatments waiting to be discovered’ inside new database

‘Treatments waiting to be discovered’ inside new database

Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to disease. Or what gene is regulated by a microRNA found in sick patients Continue reading

Growing up on livestock farm halves risk of inflammatory bowel diseases

Growing up on livestock farm halves risk of inflammatory bowel diseases

New research conducted at Aarhus University has revealed that people who have grown up on a farm with livestock are only half as likely as their urban counterparts to develop the most common inflammatory bowel diseases: ulcerative colitis and Crohn’s disease. Continue reading

New discovery in living cell signaling

New discovery in living cell signaling

A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the Ras family of proteins, one of the most important components of cellular signaling networks in biology and major drivers of cancers that are among the most difficult to treat Continue reading

Noroviruses cause around a fifth of all cases of acute gastroenteritis worldwide

Noroviruses cause around a fifth of all cases of acute gastroenteritis worldwide

Noroviruses are a leading cause of acute gastroenteritis (diarrhea and vomiting) across all age groups, responsible for almost a fifth (18%) of all cases worldwide. New estimates, published in The Lancet Infectious Diseases , highlight the importance of developing norovirus vaccines, say the authors. “Including data from 48 countries and involving more than 187,000 gastroenteritis cases worldwide, these new estimates are the largest analysis of norovirus infection and disease to date Continue reading