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Tag Archives: dna

Genetic patch ‘stops deafness’

Genetic patch ‘stops deafness’

4 February 2013 Last updated at 21:33 ET By James Gallagher Health and science reporter, BBC News A tiny “genetic patch” can be used to prevent a form of deafness which runs in families, according to animal tests. Patients with Usher syndrome have defective sections of their genetic code which cause problems with hearing, sight and balance.

New stroke gene discovery could lead to tailored treatments

New stroke gene discovery could lead to tailored treatments

Jan. 31, 2013 — A study led by King’s College London has identified a new genetic variant associated with stroke

Gene found that turns up effect of chemotherapy

Gene found that turns up effect of chemotherapy

Jan. 29, 2013 — Chemotherapy is one of the most common treatments for cancer patients

One-step test for mitochondrial diseases

One-step test for mitochondrial diseases

Jan. 28, 2013 — More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source of DNA — within the genes inside mitochondria, cellular power plants that, when abnormal, contribute to complex, multisystem diseases

New mutations discovered driving malignant melanoma

New mutations discovered driving malignant melanoma

Jan. 24, 2013 — Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the “dark matter” of the cancer genome, where cancer-related mutations haven’t been previously found.

Linchpin of skin response to UVA light discovered

Linchpin of skin response to UVA light discovered

Jan. 21, 2013 — Researchers have strengthened their understanding of how skin cells called melanocytes sense ultraviolet light and act to protect themselves with melanin. In a new study, they report experiments showing that an ion channel well-known elsewhere in the body for its chemical sensitivity, plays a central role in this process

Enzyme helps cancer cells avoid genetic instability

Enzyme helps cancer cells avoid genetic instability

Jan. 21, 2013 — Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing themselves from stagnation or death.

DNA chip to diagnose attention deficit hyperactivity disorder?

DNA chip to diagnose attention deficit hyperactivity disorder?

Jan. 21, 2013 — Attention Deficit Hyperactivity Disorder (ADHD) is the most common childhood neuropsychiatric disorder. Yet there is currently no tool that will confirm the diagnosis of ADHD

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious treatment targets

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious treatment targets

Jan. 20, 2013 — An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations — mutations that would suggest new targets for neuroblastoma treatment.

Epigenetics explains rheumatism? Genes and their regulatory ‘tags’ conspire to promote rheumatoid arthritis

Epigenetics explains rheumatism? Genes and their regulatory ‘tags’ conspire to promote rheumatoid arthritis

Jan. 20, 2013 — In one of the first genome-wide studies to hunt for both genes and their regulatory “tags” in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults.