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Tag Archives: dna

Living organ regeneration ‘first’

Living organ regeneration ‘first’

unable to retrieve full-text contentAn elderly organ in a living animal has been regenerated into a youthful state by DNA manipulation for the first time, UK researchers say. Continue reading

Seeing double: New study explains evolution of duplicate genes

Seeing double: New study explains evolution of duplicate genes

From time to time, living cells will accidentally make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity Continue reading

Seeing double: New study explains evolution of duplicate genes

Seeing double: New study explains evolution of duplicate genes

From time to time, living cells will accidentally make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity Continue reading

Gene sequencing project discovers mutations tied to deadly brain tumors in young children

Gene sequencing project discovers mutations tied to deadly brain tumors in young children

The St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high-grade gliomas (HGGs), which most often occur in the youngest patients Continue reading

Potential drug targets in deadly pediatric brain tumors

Potential drug targets in deadly pediatric brain tumors

Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and McGill University. The findings identify potential new targets for drug treatments. The new research could help physicians choose targeted agents with a better chance of combating pediatric high-grade astrocytomas, which are extremely difficult to treat with radiation and surgery Continue reading

Prognosis of tumors positive for human papilloma virus in head and neck cancers varies according to site

Prognosis of tumors positive for human papilloma virus in head and neck cancers varies according to site

Patients with cancer of the throat and who are positive for the Human Papilloma virus (HPV+) have a good prognosis, but until now the effect of being HPV+ on the prognosis of tumours located elsewhere in the head and neck was unknown. Danish researchers have now shown that HPV status appears to have no prognostic effect on the outcome of primary radiotherapy in head and neck cancer outside the oropharynx (the part of the throat located behind the mouth, and which contains the soft palate and the base of the tongue), the ESTRO 33 congress will hear today (Sunday). Presenting her results to the congress, Dr Pernille Lassen, MD, PhD, from the Aarhus University Hospital, Aarhus, Denmark, will say that head and neck cancers located outside the oropharynx should probably not be treated with the less intensive treatment strategies that are currently being investigated in clinical trials for HPV+ oropharyngeal tumours. Continue reading

New test developed to detect men at high risk of prostate cancer recurrence

New test developed to detect men at high risk of prostate cancer recurrence

A new genetic “signature” to identify prostate cancer patients who are at high risk of their cancer recurring after surgery or radiotherapy has been developed by researchers in Canada, the 33rd conference of the European Society for Radiotherapy and Oncology (ESTRO33) in Vienna will hear today (Saturday). Continue reading

Bacterial gut biome may guide colon cancer progression

Bacterial gut biome may guide colon cancer progression

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, researchers from The Wistar Institute will present findings that suggest the colon “microbiome” of gut bacteria can change the tumor microenvironment in a way that promotes the growth and spread of tumors. Their results suggest that bacterial virulence proteins may suppress DNA repair proteins within the epithelial cells that line the colon. Continue reading

Antioxidants can protect against omega 6 damage — or promote it

Antioxidants can protect against omega 6 damage — or promote it

Given omega 6 fatty acid’s reputation for promoting cancer — at least in animal studies — researchers are examining the role that antioxidants play in blocking the harmful effects of this culprit, found in many cooking oils. After all, antioxidants are supposed to prevent DNA damage. Continue reading

Carbohydrate digestion and obesity strongly linked

Carbohydrate digestion and obesity strongly linked

New research indicates that obesity in the general population may be genetically linked to how our bodies digest carbohydrates. Continue reading