List/Grid

Tag Archives: Drug

K bladder: UK’s secret ketamine epidemic

K bladder: UK’s secret ketamine epidemic

unable to retrieve full-text contentTwo ketamine users in their 20s tell Newsbeat how the drug nearly destroyed their bladders. Continue reading

Maintenance therapy for injection-drug users associated with lower incidence of hepatitis C

Maintenance therapy for injection-drug users associated with lower incidence of hepatitis C

In a group of young users of injection drugs, recent maintenance opioid agonist therapy with methadone or buprenorphine for opioid use disorders, such as heroin addiction, was associated with a lower incidence of hepatitis C virus (HCV) infection and may be an effective strategy to reduce injection-drug use and the resulting spread of HCV, according to a study published online by JAMA Internal Medicine . Continue reading

Highly effective new anti-cancer drug shows few side effects in mice

Highly effective new anti-cancer drug shows few side effects in mice

A new drug, known as OTS964, can eradicate aggressive human lung cancers transplanted into mice, according to a report in Science Translational Medicine. The drug, given as a pill or by injection, inhibits the action of a protein that is overproduced by several tumor types, including lung and breast, but is rarely expressed in healthy adult tissues Continue reading

Fingolimod in new therapeutic indication: Added benefit not proven, study finds

Fingolimod in new therapeutic indication: Added benefit not proven, study finds

The immunosuppressive drug fingolimod (trade name: Gilenya) was approved for an expanded therapeutic indication in May 2014: It is now also available for adults with highly active relapsing remitting multiple sclerosis (RRMS) who had received other pretreatment than interferon beta (IFN-β). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether the drug offers an added benefit over the appropriate comparator therapy in this patient group. According to the findings, such an added benefit is not proven: For some of the patients, the drug manufacturer presented no data. Continue reading

Drug-infused nanoparticle is right for sore eyes

Drug-infused nanoparticle is right for sore eyes

For the millions of sufferers of dry eye syndrome, their only recourse to easing the painful condition is to use drug-laced eye drops three times a day. Now, researchers from the University of Waterloo have developed a topical solution containing nanoparticles that will combat dry eye syndrome with only one application a week. The eye drops progressively deliver the right amount of drug-infused nanoparticles to the surface of the eyeball over a period of five days before the body absorbs them. Continue reading

Drug-infused nanoparticle is right for sore eyes

Drug-infused nanoparticle is right for sore eyes

For the millions of sufferers of dry eye syndrome, their only recourse to easing the painful condition is to use drug-laced eye drops three times a day. Now, researchers from the University of Waterloo have developed a topical solution containing nanoparticles that will combat dry eye syndrome with only one application a week. The eye drops progressively deliver the right amount of drug-infused nanoparticles to the surface of the eyeball over a period of five days before the body absorbs them. Continue reading

New drug-delivery capsule may replace injections

New drug-delivery capsule may replace injections

Given a choice, most patients would prefer to take a drug orally instead of getting an injection. Continue reading

Perampanel for epilepsy: Still no proof of added benefit

Perampanel for epilepsy: Still no proof of added benefit

The drug perampanel (trade name Fycompa) has been approved since July 2012 as adjunctive (“add-on”) therapy for adults and children aged 12 years and older with epileptic fits (seizures). In a new early benefit assessment according to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether perampanel offers an added benefit over the appropriate comparator therapy. However, such an added benefit cannot be derived from the new dossier either, as the drug manufacturer did not submit any relevant data for this comparison Continue reading

New culprit identified in metabolic syndrome

New culprit identified in metabolic syndrome

A new study suggests uric acid may play a role in causing metabolic syndrome, a cluster of risk factors that increases the risk of heart disease and type 2 diabetes. Uric acid is a normal waste product removed from the body by the kidneys and intestines and released in urine and stool. Continue reading

Trapped: Cell-invading piece of virus captured in lab by scientists

Trapped: Cell-invading piece of virus captured in lab by scientists

In recent research published in the Journal of Biological Chemistry , Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a drug designed to thwart it. This achievement sets the stage to use x-ray crystallography to develop complete images of HIV that include integrase, which in turn will help scientists develop new treatments for the illness. Duane Grandgenett, Ph.D., professor at SLU’s Institute of Molecular Virology and senior author of the study, discovered integrase in 1978, little knowing the piece of virus would provide the basis for an entire class of drugs that now treats HIV. Continue reading