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Tag Archives: Drugs

Bio-inspired ‘nano-cocoons’ offer targeted drug delivery against cancer cells

Bio-inspired ‘nano-cocoons’ offer targeted drug delivery against cancer cells

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale “cocoons” made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. The work was done by researchers at North Carolina State University and the University of North Carolina at Chapel Hill. “This drug delivery system is DNA-based, which means it is biocompatible and less toxic to patients than systems that use synthetic materials,” says Dr. Continue reading

Bio-inspired ‘nano-cocoons’ offer targeted drug delivery against cancer cells

Bio-inspired ‘nano-cocoons’ offer targeted drug delivery against cancer cells

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale “cocoons” made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. The work was done by researchers at North Carolina State University and the University of North Carolina at Chapel Hill. “This drug delivery system is DNA-based, which means it is biocompatible and less toxic to patients than systems that use synthetic materials,” says Dr. Continue reading

Intracranial stents: More strokes than with drug treatment alone

Intracranial stents: More strokes than with drug treatment alone

The risk of having another stroke is higher if patients, after dilation of their blood vessels in the brain, not only receive clot-inhibiting drugs, but also have small tubes called stents inserted. However, studies have provided no hint of a benefit from stenting, which is also referred to with the abbreviation “PTAS.” This is the conclusion reached in the rapid report of the German Institute for Quality and Efficiency in Health Care (IQWiG), as published on 9 October 2014. Stents are supposed to prevent restenosis Blood vessels in the brain that are narrowed or blocked can cause stroke. Continue reading

New drug-delivery capsule may replace injections

New drug-delivery capsule may replace injections

Given a choice, most patients would prefer to take a drug orally instead of getting an injection. Continue reading

Trastuzumab should remain as standard of care for HER2-positive breast cancer, trial suggests

Trastuzumab should remain as standard of care for HER2-positive breast cancer, trial suggests

Analysis of more than 8,000 women who participated in the world’s largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a Mayo Clinic researcher. This study, being presented at the European Society for Medical Oncology (ESMO) 2014 Congress in Madrid, reveals that when used as a single HER2-targeted therapy in addition to standard chemotherapy, trastuzumab offers a better outcome than does lapatinib (Tykerb), says Edith A. Continue reading

New hepatitis c medication in children to be studied

New hepatitis c medication in children to be studied

After the success of a new drug treatment in adults with hepatitis C infection, a Saint Louis University pediatric researcher is testing the safety and efficacy of the medications in children. Part of a multi-center clinical study, SLU is the only center in the region that will examine a combination of two drugs — Sofosbuvir and Ribavirin — in children between ages 3 and 17 Continue reading

New statin guidelines an improvement, study shows

New statin guidelines an improvement, study shows

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a Yale University study has found. The research, published Aug. 25 in the Journal of the American College of Cardiology , also showed the new guidelines produce only a modest increase in the number of patients being given the drugs Continue reading

New shock-and-kill approach could eradicate barrier to curing HIV

New shock-and-kill approach could eradicate barrier to curing HIV

Despite tremendous progress in combatting HIV-1 infection with antiretroviral therapy, there is still no cure for the disease because these drugs do not kill a hidden reservoir of infected cells in the body. Continue reading

Dimethyl fumarate for MS: Added benefit not proven

Dimethyl fumarate for MS: Added benefit not proven

Dimethyl fumarate (trade name: Tecfidera) has been approved since January 2014 for adults with relapsing remitting multiple sclerosis (RRMS). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) has examined whether this new drug for MS offers an added benefit over the appropriate comparator therapy specified by the Federal Joint Committee (G-BA). However, no added benefit can be determined, as no suitable data are available, neither for the direct nor for the indirect comparison. Continue reading

Brief counseling for drug use doesn’t work

Brief counseling for drug use doesn’t work

In an effort to stem substance use, the U.S. has invested heavily in the past decade in a brief screening-and-intervention protocol for alcohol and other drugs. But a new study by Boston University School of Public Health and School of Medicine researchers casts doubt on whether that approach, which has proven successful with risky alcohol use, works for illicit drugs Continue reading