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Surprising twist to protein misfolding discovered

Surprising twist to protein misfolding discovered

Jan.

Surprising twist to protein misfolding discovered

Surprising twist to protein misfolding discovered

Jan. 14, 2013 — An effort to develop software that unravels the complexities of how proteins fold is paying dividends in new findings on how they misfold, according to researchers at Rice University. The study published this week in the Proceedings of the National Academy of Sciences by chemist Peter Wolynes and his team at Rice’s BioScience Research Collaborative should be of particular interest to those who probe the roots of degenerative diseases associated with the aggregation of amyloid fibers in the body

Cancer suppressor gene links metabolism with cellular aging

Cancer suppressor gene links metabolism with cellular aging

Jan. 13, 2013 — It is perhaps impossible to overstate the importance of the tumor suppressor gene p53. It is the single most frequently mutated gene in human tumors.

Important factor in fat storage and energy metabolism

Important factor in fat storage and energy metabolism

Jan. 6, 2013 — As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator — TRIP-Br2 — that plays a major role in energy metabolism and fat storage. This finding has the potential to lead to new treatments for obesity

Important factor in fat storage and energy metabolism

Important factor in fat storage and energy metabolism

Jan. 6, 2013 — As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator — TRIP-Br2 — that plays a major role in energy metabolism and fat storage. This finding has the potential to lead to new treatments for obesity

Gene variant linked to active personality traits also linked to human longevity

Gene variant linked to active personality traits also linked to human longevity

Jan. 3, 2013 — A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found. This derivative of a dopamine-receptor gene — called the DRD4 7R allele — appears in significantly higher rates in people more than 90 years old and is linked to lifespan increases in mouse studies.

The HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer

The HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer

Dec. 14, 2012 — A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis and treatment of breast cancer.

Novel laser technique reveals how the inner ear amplifies sound

Novel laser technique reveals how the inner ear amplifies sound

Dec. 11, 2012 — It has long been known that the inner ear actively amplifies sounds it receives, and that this amplification can be attributed to forces generated by outer hair cells in the cochlea

Optogenetics illuminates pathways of motivation through brain

Optogenetics illuminates pathways of motivation through brain

ScienceDaily (Nov. 18, 2012) — Whether you are an apple tree or an antelope, survival depends on using your energy efficiently

Sugar boosts self-control

Sugar boosts self-control

ScienceDaily (Nov. 7, 2012) — To boost self-control, gargle sugar water. According to a study co-authored by University of Georgia professor of psychology Leonard Martin published Oct.