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Tag Archives: Energy

Young dads at high risk of depression, too

Young dads at high risk of depression, too

Depression can hit young fathers hard — with symptoms increasing dramatically during some of the most important years of their children’s lives, a new Northwestern Medicine® study has found. Continue reading

Epilepsy drug target implications for sleep disruption in brain disorders

Epilepsy drug target implications for sleep disruption in brain disorders

A new study in a mutant fruitfly called sleepless (sss) confirmed that the enzyme GABA transaminase, which is the target of some epilepsy drugs, contributes to sleep loss. The findings, published online in Molecular Psychiatry , were led by Amita Sehgal, PhD, head of the Chronobiology Program at the University of Pennsylvania’s Perelman School of Medicine Continue reading

Gulf war illness not in veterans’ heads but in their mitochondria

Gulf war illness not in veterans’ heads but in their mitochondria

Researchers at the UC San Diego School of Medicine have demonstrated for the first time that veterans of the 1990-91 Persian Gulf War who suffer from “Gulf War illness” have impaired function of mitochondria — the energy powerhouses of cells. The findings, published in the March 27, 2014 issue of PLOS ONE , could help lead to new treatments benefitting affected individuals — and to new ways of protecting servicepersons (and civilians) from similar problems in the future, said principal investigator Beatrice A Continue reading

Gulf war illness not in veterans’ heads but in their mitochondria

Gulf war illness not in veterans’ heads but in their mitochondria

Researchers at the UC San Diego School of Medicine have demonstrated for the first time that veterans of the 1990-91 Persian Gulf War who suffer from “Gulf War illness” have impaired function of mitochondria — the energy powerhouses of cells. The findings, published in the March 27, 2014 issue of PLOS ONE , could help lead to new treatments benefitting affected individuals — and to new ways of protecting servicepersons (and civilians) from similar problems in the future, said principal investigator Beatrice A. Golomb MD, PhD, professor of medicine Continue reading

Fast and reliable: New mechanism for speedy transmission in basket cells discovered

Fast and reliable: New mechanism for speedy transmission in basket cells discovered

In his third major research paper since December 2013, IST Austria Professor Peter Jonas together with his collaborator, postdoc Hua Hu, identifies a new subcellular mechanism for reliable, fast transmission in the so-called basket cells of the brain. The results will be published on the website of Nature Neuroscience on March 23, 2014. IST Austria president Thomas Henzinger expressed his delight: “This is an extraordinary streak of publications in major journals which once more emphasizes the outstanding work of Peter Jonas and his group Continue reading

Surprising twist to protein misfolding discovered

Surprising twist to protein misfolding discovered

Jan. Continue reading

Surprising twist to protein misfolding discovered

Surprising twist to protein misfolding discovered

Jan. 14, 2013 — An effort to develop software that unravels the complexities of how proteins fold is paying dividends in new findings on how they misfold, according to researchers at Rice University. The study published this week in the Proceedings of the National Academy of Sciences by chemist Peter Wolynes and his team at Rice’s BioScience Research Collaborative should be of particular interest to those who probe the roots of degenerative diseases associated with the aggregation of amyloid fibers in the body Continue reading

Cancer suppressor gene links metabolism with cellular aging

Cancer suppressor gene links metabolism with cellular aging

Jan. 13, 2013 — It is perhaps impossible to overstate the importance of the tumor suppressor gene p53. It is the single most frequently mutated gene in human tumors. Continue reading

Important factor in fat storage and energy metabolism

Important factor in fat storage and energy metabolism

Jan. 6, 2013 — As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator — TRIP-Br2 — that plays a major role in energy metabolism and fat storage. This finding has the potential to lead to new treatments for obesity Continue reading

Important factor in fat storage and energy metabolism

Important factor in fat storage and energy metabolism

Jan. 6, 2013 — As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator — TRIP-Br2 — that plays a major role in energy metabolism and fat storage. This finding has the potential to lead to new treatments for obesity Continue reading