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Tag Archives: Genetics

DNA signature found in Ice Storm babies: Prenatal maternal stress exposure to natural disasters predicts epigenetic profile of offspring

DNA signature found in Ice Storm babies: Prenatal maternal stress exposure to natural disasters predicts epigenetic profile of offspring

The number of days an expectant mother was deprived of electricity during Quebec’s Ice Storm (1998) predicts the epigenetic profile of her child, a new study finds. Scientists from the Douglas Mental Health University Institute and McGill University have detected a distinctive ‘signature’ in the DNA of children born in the aftermath of the massive Quebec ice storm Continue reading

Policies of NIH, other funders, have improved data-sharing by life-science investigators

Policies of NIH, other funders, have improved data-sharing by life-science investigators

Policies put into place by major funding agencies like the National Institutes of Health (NIH), and to a lesser extent by scientific journals, appear to be meeting the goal of increasing the sharing of scientific resources among life science investigators. As reported in the open-access journal PLOS ONE , 65 percent of surveyed investigators at major U.S. research institutions believed that NIH policies instituted in recent years had markedly improved the sharing of scientific data Continue reading

New analysis of human genetic history reveals female dominance

New analysis of human genetic history reveals female dominance

Female populations have been larger than male populations throughout human history, according to research published today in the open access journal Investigative Genetics . The research used a new technique to obtain higher quality paternal genetic information to analyze the demographic history of males and females in worldwide populations Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Lack of thyroid hormone blocks hearing development

Lack of thyroid hormone blocks hearing development

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration — these symptoms are a few of the signs that the thyroid gland, which regulates the body’s heart rate and plays a crucial role in its metabolism, has gone haywire. Now, new research from Tel Aviv University points to an additional complication caused by thyroid imbalance: congenital deafness. Continue reading

Genetically driven gut feelings help female flies choose a mate

Genetically driven gut feelings help female flies choose a mate

Even among flies, mating is a complicated ritual. Their elaborate, and entirely innate, courtship dance combines multiple motor skills with advanced sensory cues. Now, researchers at Rockefeller University have determined that the Abdominal-B ( Abd-B ) gene, previously known as the gene that sculpts the posterior parts of the developing fly, is also important for this complex behavior, at least in the case of female flies ( Drosophila melanogaster) Continue reading

Gene responsible for traits involved in diabetes discovered

Gene responsible for traits involved in diabetes discovered

A collaborative research team led by Medical College of Wisconsin (MCW) scientists has identified a new gene associated with fasting glucose and insulin levels in rats, mice and in humans. The findings are published in the September issue of Genetics Continue reading

How epigenetic memory is passed through generations: Sperm and eggs transmit memory of gene repression to embryos

How epigenetic memory is passed through generations: Sperm and eggs transmit memory of gene repression to embryos

A growing body of evidence suggests that environmental stresses can cause changes in gene expression that are transmitted from parents to their offspring, making “epigenetics” a hot topic. Epigenetic modifications do not affect the DNA sequence of genes, but change how the DNA is packaged and how genes are expressed. Continue reading

Melanoma risk found to have genetic determinant

Melanoma risk found to have genetic determinant

A leading Dartmouth researcher, working with The Melanoma Genetics Consortium, GenoMEL, an international research consortium, co-authored a paper published in the Journal of the National Cancer Institute that proves longer telomeres increase the risk of melanoma. “For the first time, we have established that the genes controlling the length of these telomeres play a part in the risk of developing melanoma,” said lead author of the study Mark Iles, PhD, School of Medicine at the University of Leeds (UK). Telomeres are a part of the genome that function like the plastic caps of your shoelaces, which prevent the laces from fraying Continue reading