List/Grid

Tag Archives: Genetics

YEATS protein potential therapeutic target for cancer

YEATS protein potential therapeutic target for cancer

Federal Express® and UPS® are no match for the human body when it comes to distribution. Continue reading

See-through sensors open new window into the brain

See-through sensors open new window into the brain

Developing invisible implantable medical sensor arrays, a team of University of Wisconsin-Madison engineers has overcome a major technological hurdle in researchers’ efforts to understand the brain. Continue reading

See-through sensors open new window into the brain

See-through sensors open new window into the brain

Developing invisible implantable medical sensor arrays, a team of University of Wisconsin-Madison engineers has overcome a major technological hurdle in researchers’ efforts to understand the brain. The team described its technology, which has applications in fields ranging from neuroscience to cardiac care and even contact lenses, in the Oct. 20 issue of the online journal Nature Communications Continue reading

Gene duplications associated with autism evolved recently in human history

Gene duplications associated with autism evolved recently in human history

Human geneticists have discovered that a region of the genome associated with autism contains genetic variation that evolved in the last 250,000 years, after the divergence of humans from ancient hominids, and likely plays an important role in disease. Their findings were presented at the American Society of Human Genetics (ASHG) 2014 Annual Meeting in San Diego. Researchers at the University of Washington analyzed the genomes of 2,551 humans, 86 apes, one Neanderthal, and one Denisovan Continue reading

Mutation associated with cleft palate in humans, dogs identified

Mutation associated with cleft palate in humans, dogs identified

Scientists studying birth defects in humans and purebred dogs have identified an association between cleft lip and cleft palate — conditions that occur when the lip and mouth fail to form properly during pregnancy — and a mutation in the ADAMTS20 gene. Continue reading

Children’s genes affect their mothers’ risk of rheumatoid arthritis

Children’s genes affect their mothers’ risk of rheumatoid arthritis

A child’s genetic makeup may contribute to his or her mother’s risk of rheumatoid arthritis, possibly explaining why women are at higher risk of developing the disease than men. This research will be presented October 21, at the American Society of Human Genetics (ASHG) 2014 Annual Meeting in San Diego. Rheumatoid arthritis, a painful inflammatory condition that primarily affects the joints, has been tied to a variety of genetic and environmental factors, including lifestyle factors and previous infections. Continue reading

New test scans all genes simultaneously to identify single mutation causing child’s rare genetic disease

New test scans all genes simultaneously to identify single mutation causing child’s rare genetic disease

Audrey Lapidus adored her baby’s sunny smile and irresistible dimples, but grew worried when Calvin did not roll over or crawl by 10 months and suffered chronic digestive problems. Four neurologists dismissed his symptoms and a battery of tests proved inconclusive. Desperate for answers, Audrey and her husband agreed to have their son become UCLA’s first patient to undergo a powerful new test called exome sequencing. Continue reading

New test scans all genes simultaneously to identify single mutation causing child’s rare genetic disease

New test scans all genes simultaneously to identify single mutation causing child’s rare genetic disease

Audrey Lapidus adored her baby’s sunny smile and irresistible dimples, but grew worried when Calvin did not roll over or crawl by 10 months and suffered chronic digestive problems. Four neurologists dismissed his symptoms and a battery of tests proved inconclusive Continue reading

High-speed evolution in the lab: Geneticists evaluate cost-effective genome analysis

High-speed evolution in the lab: Geneticists evaluate cost-effective genome analysis

Life implies change. And this holds true for genes as well. Organisms require a flexible genome in order to adapt to changes in the local environment. Continue reading

Reproducibility score for SNPs associated with human disease in GWAS

Reproducibility score for SNPs associated with human disease in GWAS

To reduce false positives when identifying genetic variations associated with human disease through genome-wide association studies (GWAS), Dartmouth researchers have identified nine traits that are not dependent on P values to predict single nucleotide polymorphisms (SNP) reproducibility as reported in Human Genetics on October 2, 2014. Continue reading