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Tag Archives: German

Brain development in schizophrenia strays from normal path

Brain development in schizophrenia strays from normal path

Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability. The normal path for brain development is determined by the combined effects of a complex network of genes and a wide range of environmental factors. Continue reading

Avatars make the Internet sign to deaf people

Avatars make the Internet sign to deaf people

It is challenging for deaf people to learn a sound-based language, since they are physically not able to hear those sounds. Hence, most of them struggle with written language as well as with text reading and comprehension. Continue reading

Perampanel for epilepsy: Still no proof of added benefit

Perampanel for epilepsy: Still no proof of added benefit

The drug perampanel (trade name Fycompa) has been approved since July 2012 as adjunctive (“add-on”) therapy for adults and children aged 12 years and older with epileptic fits (seizures). In a new early benefit assessment according to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether perampanel offers an added benefit over the appropriate comparator therapy. However, such an added benefit cannot be derived from the new dossier either, as the drug manufacturer did not submit any relevant data for this comparison Continue reading

Work-related stress a risk factor for type 2 diabetes

Work-related stress a risk factor for type 2 diabetes

Workplace stress can have a range of adverse effects on health with an increased risk of cardio-vascular diseases in the first line. However, to date, convincing evidence for a strong association between work stress and incident Type 2 diabetes mellitus is missing. Continue reading

Key component of cell division comes to light

Key component of cell division comes to light

The division of a cell in two requires the assembly of the mitotic spindle, an extremely complex structure, which is the result of the coordinated action of a multitude of proteins and a finely tuned balance of their activities. Continue reading

Triggers, treatment of immediate-type allergic reactions

Triggers, treatment of immediate-type allergic reactions

Sudden allergic reactions can be fatal. The most common triggers of such reactions, also known as anaphylaxis, are wasp and bee venoms, legumes (pulses), animal proteins, and analgesics (painkillers). The incidence of anaphylaxis is age-dependent. Continue reading

HPV testing: Benefit in primary screening

HPV testing: Benefit in primary screening

The Institute for Quality and Efficiency in Health Care (IQWiG) assessed current study results on the benefit of a test for human papillomavirus (HPV) and examined whether its first assessment from January 2012 is still valid. Continue reading

Mitochondrial DNA of first Near Eastern farmers is sequenced for the first time

Mitochondrial DNA of first Near Eastern farmers is sequenced for the first time

The mitochondrial DNA of the first Near Eastern farmers has been sequenced for the first time. In the research, published in the journal PLOS Genetics , experts analysed samples from three sites located in the birthplace of Neolithic agricultural practices: the Middle Euphrates basin and the oasis of Damascus, located in today’s Syria and date at about 8,000 BC. The paper is signed by Daniel Turbón and Alejandro Pérez Pérez, from the Department of Animal Biology of the University of Barcelona (UB); Eva Fernández, from Liverpool John Moores University; Cristina Gamba, Eduardo Arroyo Pardo and Pedro Cuesta, from Complutense University of Madrid; Eva Prats, from the Spanish National Research Council, and Josep Anfruns and Miquel Molist, from the Universitat Autònoma de Barcelona (UAB). Continue reading

Decoding how the brain miswires, possibly causing ADHD

Decoding how the brain miswires, possibly causing ADHD

Neuroscientists at Mayo Clinic in Florida and at Aarhus University in Denmark have shed light on why neurons in the brain’s reward system can be miswired, potentially contributing to disorders such as attention deficit hyperactivity disorder (ADHD). They say findings from their study, published online today in Neuron , may increase the understanding of underlying causes of ADHD, potentially facilitating the development of more individualized treatment strategies Continue reading

Sperm-inspired robots controlled by magnetic fields may be useful for drug delivery, IVF, cell sorting and other applications

Sperm-inspired robots controlled by magnetic fields may be useful for drug delivery, IVF, cell sorting and other applications

A team of researchers at the University of Twente (Netherlands) and German University in Cairo (Egypt) has developed sperm-inspired microrobots, which can be controlled by oscillating weak magnetic fields. Described in a cover article in the journal Applied Physics Letters , which is from AIP Publishing, the 322 micron-long robots consist solely of a head coated in a thick cobalt-nickel layer and an uncoated tail. Continue reading