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Tag Archives: Immunology

Cell receptor has proclivity for T helper 9 cells, airway inflammation

Cell receptor has proclivity for T helper 9 cells, airway inflammation

ScienceDaily (July 29, 2012) — A research team led by Xian Chang Li, MD, PhD, Brigham and Women’s Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult T helper cells. Continue reading

Discovery of new white blood cell reveals target for better vaccine design

Discovery of new white blood cell reveals target for better vaccine design

ScienceDaily (July 27, 2012) — Researchers in Newcastle and Singapore have identified a new type of white blood cell which activates a killing immune response to an external source — providing a new potential target for vaccines for conditions such as cancer or Hepatitis B. Publishing in the journal Immunity , the team of researchers from Newcastle University in collaboration with A*STAR’s Singapore Immunology Network (SIgN) describe a new human tissue dendritic cell with cross-presenting function. Dendritic cells (DCs) are a type of white blood cell that orchestrate our body’s immune responses to infectious agents such as bacteria and viruses, as well as cancer cells. Continue reading

New class of synthetic vaccines explored

New class of synthetic vaccines explored

ScienceDaily (July 25, 2012) — In a quest to make safer and more effective vaccines, scientists at the Biodesign InstituteÒ at Arizona State University have turned to a promising field called DNA nanotechnology to make an entirely new class of synthetic vaccines. Continue reading

New target for vaccine development in abundant immune cells

New target for vaccine development in abundant immune cells

ScienceDaily (July 24, 2012) — White blood cells called neutrophils, which are the first line of defense against infection, play an unexpected role by boosting antibody production, according to research led by Mount Sinai School of Medicine. The findings suggest neutrophils have multiple roles within the immune system and function at levels previously unknown to the scientific community Continue reading

Short-term intestinal parasite infection triggers specific cytokines that can prevent the development of type 1 diabetes

Short-term intestinal parasite infection triggers specific cytokines that can prevent the development of type 1 diabetes

ScienceDaily (July 18, 2012) — Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School. Continue reading

‘Egg therapy’ shows promise for treatment of egg allergies

‘Egg therapy’ shows promise for treatment of egg allergies

ScienceDaily (July 18, 2012) — Giving children with egg allergies increasingly higher doses of the very food they are allergic to can eliminate or ease reactions in most of them, according to results from a federally funded study conducted at Johns Hopkins Children’s Center and four other U.S. institutions. The research findings, published July 19 in the New England Journal of Medicine , add to a growing body of evidence showing that feeding escalating doses of a food — an approach known as oral immunotherapy — can, over time, condition the immune system to tolerate the food with minimal or no reactions Continue reading

Kawasaki disease in childhood linked to increased risk of adult heart disease

Kawasaki disease in childhood linked to increased risk of adult heart disease

ScienceDaily (July 17, 2012) — Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults. In a study published in the August 2012 print edition of Arteriosclerosis, Thrombosis, and Vascular Biology , an American Heart Association peer-reviewed medical journal, a team of researchers showed how Kawasaki Disease in young mice predisposed them to develop accelerated atherosclerosis, often called hardening of the arteries, in young adulthood. The study also suggests that aggressive early treatment of the blood vessel inflammation caused by Kawasaki Disease may reduce the future risk of developing accelerated atherosclerosis. Continue reading

Kawasaki disease in childhood linked to increased risk of adult heart disease

Kawasaki disease in childhood linked to increased risk of adult heart disease

ScienceDaily (July 17, 2012) — Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults. In a study published in the August 2012 print edition of Arteriosclerosis, Thrombosis, and Vascular Biology , an American Heart Association peer-reviewed medical journal, a team of researchers showed how Kawasaki Disease in young mice predisposed them to develop accelerated atherosclerosis, often called hardening of the arteries, in young adulthood. The study also suggests that aggressive early treatment of the blood vessel inflammation caused by Kawasaki Disease may reduce the future risk of developing accelerated atherosclerosis. Continue reading

How aging impairs immune response

How aging impairs immune response

ScienceDaily (July 17, 2012) — Researchers at Albert Einstein College of Medicine of Yeshiva University have uncovered one of the mechanisms by which aging may compromise the ability of the immune system to fight infections and respond to vaccines. The study, conducted in aging mice, shows that administering antioxidants may help reverse this loss of immune function. The findings were published online this month in the journal Cell Reports . Continue reading

£20m donation for Cancer research

£20m donation for Cancer research

17 July 2012 Last updated at 12:50 ET By Susan Watts Newsnight Science editor, BBC News A donor, who wishes to remain anonymous, has given £20m to fund cancer immunology in the UK, BBC’s Newsnight has learnt. Harnessing the immune system is seen as a promising new area of treatment, but raising funding has become harder. The money will be equally split between the Francis Crick Institute for medical research and University of Southampton. Continue reading