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FDG-PET/CT shows promise for breast cancer patients younger than 40

FDG-PET/CT shows promise for breast cancer patients younger than 40

Researchers at Memorial Sloan Kettering found that PET/CT imaging of patients younger than 40 who were initially diagnosed with stage I-III breast cancer resulted in change of diagnosis. As reported in the October issue of The Journal of Nuclear Medicine , while guidelines recommend FDG-PET/CT imaging only for women with stage III breast cancer, it can also help physicians more accurately diagnose young breast cancer patients initially diagnosed with earlier stages of the disease. Continue reading

Depression increasing across the United States

Depression increasing across the United States

A study by San Diego State University psychology professor Jean M. Twenge shows Americans are more depressed now than they have been in decades Continue reading

High-speed drug screen developed

High-speed drug screen developed

MIT engineers have devised a way to rapidly test hundreds of different drug-delivery vehicles in living animals, making it easier to discover promising new ways to deliver a class of drugs called biologics, which includes antibodies, peptides, RNA, and DNA, to human patients. In a study appearing in the journal Integrative Biology , the researchers used this technology to identify materials that can efficiently deliver RNA to zebrafish and also to rodents. This type of high-speed screen could help overcome one of the major bottlenecks in developing disease treatments based on biologics: It is challenging to find safe and effective ways to deliver them Continue reading

How to predict who will suffer the most from stress

How to predict who will suffer the most from stress

More than 23 per cent of Canadians report being stressed or very stressed on most days. While chronic stress increases the risk of poor mental and physical health, not everyone is affected the same way. Some cope well, but for others — especially those most likely to sweat the small stuff — chronic stress can be harmful. Continue reading

Potential biomarker to detect SCID (severe combined immunodeficiency)

Potential biomarker to detect SCID (severe combined immunodeficiency)

A genetic disease called SCID, short for severe combined immunodeficiency, forces patients to breathe filtered air and avoid human contact because their bodies’ natural defenses are too weak to fight germs. Although it affects fewer than 2,000 new births each year worldwide, SCID is a cousin to acquired immune deficiency syndrome triggered by a human immunodeficiency virus — HIV/AIDS Continue reading

New blood test determines whether you have or are likely to get cancer

New blood test determines whether you have or are likely to get cancer

A new research report published in the October 2014 issue of The FASEB Journal may make the early detection of cancer as easy as a simple blood test. This test, called the “lymphocyte genome sensitivity” (LGS) test, could not only detect some cancers earlier than ever before, but it may eliminate the need for some types of biopsies, as well as identify those more likely to develop cancer in the future. “The test could allow earlier cancer detection, so helping to save peoples’ lives,” said Diana Anderson, a researcher involved in the work from the School of Life Sciences at the University of Bradford in West Yorkshire, United Kingdom Continue reading

Scientists identify which genes are active in muscles of men, women

Scientists identify which genes are active in muscles of men, women

If you want your doctor to know what goes wrong with your muscles because of age, disease or injury, it’s a good idea to know what “normal” actually is. Continue reading

Adolescent exposure to THC may cause immune systems to go up in smoke

Adolescent exposure to THC may cause immune systems to go up in smoke

When it comes to using marijuana, new research, involving mice and published in the October 2014 issue of the Journal of Leukocyte Biology , suggests that just because you can do it, doesn’t mean that you should. That’s because a team of Italian scientists have found that using marijuana in adolescence may do serious long-term damage to the immune system. This damage may result in autoimmune diseases and chronic inflammatory diseases, such as multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis in adulthood. Continue reading

An apple a day could keep obesity away

An apple a day could keep obesity away

Scientists at Washington State University have concluded that nondigestible compounds in apples — specifically, Granny Smith apples — may help prevent disorders associated with obesity. The study, thought to be the first to assess these compounds in apple cultivars grown in the Pacific Northwest, appears in October’s print edition of the journal Food Chemistry. “We know that, in general, apples are a good source of these nondigestible compounds but there are differences in varieties,” said food scientist Giuliana Noratto, the study’s lead researcher. Continue reading

Early sign of pancreatic cancer identified by researchers

Early sign of pancreatic cancer identified by researchers

Scientists at Dana-Farber Cancer Institute, the Massachusetts Institute of Technology, and other institutions have discovered a sign of the early development of pancreatic cancer – an upsurge in certain amino acids that occurs before the disease is diagnosed and symptoms appear. The research is being published online today by the journal Nature Medicine . Although the increase isn’t large enough to be the basis of a new test for early detection of the disease, the findings will help researchers better understand how pancreatic cancer affects the rest of the body, particularly how it can trigger the sometimes deadly muscle-wasting disease known as cachexia. Continue reading