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Tag Archives: Journal

Conspicuous tRNA lookalikes riddle the human genome

Conspicuous tRNA lookalikes riddle the human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly. A new discovery suggests that the number of human genomic loci that might be coding for tRNAs is nearly double what is currently known. Most of the newly identified loci resemble the sequences of mitochondrial tRNAs suggesting unexpected new links between the human nuclear and mitochondrial genomes, links that are not currently understood Continue reading

Fundamental theory about education of immune police questioned by researchers

Fundamental theory about education of immune police questioned by researchers

A fundamental theory about how our thymus educates our immune police appears to be wrong, scientists say. It’s known that stem cells come out of the bone marrow and travel to the tiny thymus gland behind the breastbone to learn to become one of two CD4T cell types: one leads an attack, the other keeps the peace. One widely held concept of why they become one or the other is that, despite coming from the same neighborhood and going to the same school, they are exposed to different things in the thymus, said Dr. Continue reading

Survival molecule helps cancer cells hide from the immune system

Survival molecule helps cancer cells hide from the immune system

A molecule that helps cancer cells evade programmed self-destruction, an internal source of death, might also help malignant cells hide from the immune system, an external source of death. A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J Continue reading

A diet for the cell: Keeping DNA fit with fewer calories

A diet for the cell: Keeping DNA fit with fewer calories

Cells are generally able to repair spontaneous damage that arises in their genetic material. Unfortunately, the DNA repair process is not perfect and sometimes, damaged DNA gets passed on to newly made cells Continue reading

Small molecule ‘jams the switch’ to prevent inflammatory cell death

Small molecule ‘jams the switch’ to prevent inflammatory cell death

Walter and Eliza Hall Institute scientists have discovered a small molecule that blocks a form of cell death that triggers inflammation, opening the door for potential new treatments for inflammatory disease such as rheumatoid arthritis, Crohn’s disease and psoriasis. The researchers made the discovery while investigating how a protein called MLKL kills cells in a process known as necroptosis. Their findings were published today in the journal Proceedings of the National Academy of Sciences . Continue reading

New vaccines targeting adults, teens are best chance to eliminate TB by 2050

New vaccines targeting adults, teens are best chance to eliminate TB by 2050

Targets to eliminate tuberculosis (TB) by 2050 are more likely to be met if new vaccines are developed for adults and adolescents instead of for infants, according to new research published in the journal Proceedings of the National Academy of Sciences . Continue reading

Doctors prescribe more painkillers to women, study confirms

Doctors prescribe more painkillers to women, study confirms

Regardless of the pain type, age and social class, women are more likely to be prescribed analgaesia than men. Continue reading

Breakthrough allows researchers to watch molecules

Breakthrough allows researchers to watch molecules

A new crystallographic technique developed at the University of Leeds is set to transform scientists’ ability to observe how molecules work. Continue reading

Healthy knowledge management and social networking

Healthy knowledge management and social networking

Social network analysis could improve knowledge sharing in the healthcare sector, according to research results published in the International Journal of Collaborative Enterprise . Elizabeth Cudney, Steven Corns and Suzanna Long in the department of Engineering Management and Systems Engineering at Missouri University of Science and Technology, in Rolla, Missouri, USA, explain how knowledge management systems (KMS) can be critical in capturing, retaining and communicating project results and staff knowledge Continue reading

A family meal a day may keep obesity away

A family meal a day may keep obesity away

Increasing rates of adolescent obesity and the likelihood that obesity will carry forward into adulthood, have led to various preventive initiatives. It has been suggested that family meals, which tend to include fruits, vegetables, calcium, and whole grains, could be protective against obesity. In a new study scheduled for publication in The Journal of Pediatrics, researchers studied whether frequent family meals during adolescence were protective for overweight and obesity in adulthood Continue reading