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Tag Archives: laboratory

Penicillin redux: Rearming proven warriors for the 21st century

Penicillin redux: Rearming proven warriors for the 21st century

Penicillin, one of the scientific marvels of the 20 th century, is currently losing a lot of battles it once won against bacterial infections. But scientists at the University of South Carolina have just reported a new approach to restoring its combat effectiveness, even against so-called “superbugs.” Bacteria have been chipping away at the power of the penicillin family of drugs since their first wide-scale use as antibiotics in the 1940s Continue reading

Lashing out at your spouse? Check your blood sugar

Lashing out at your spouse? Check your blood sugar

Lower levels of blood sugar may make married people angrier at their spouses and even more likely to lash out aggressively, new research reveals. In a 21-day study, researchers found that levels of blood glucose in married people, measured each night, predicted how angry they would be with their spouse that evening. At the end of the 21 days, people who had generally lower levels of glucose were willing to blast their spouses with unpleasant noises at a higher volume and for a longer time than those who had higher glucose levels. Continue reading

Doctors implant lab-grown vagina

Doctors implant lab-grown vagina

unable to retrieve full-text contentFour women have had new vaginas grown in the laboratory and implanted by doctors in the US. Continue reading

Doctors implant lab-grown vagina

Doctors implant lab-grown vagina

unable to retrieve full-text contentFour women have had new vaginas grown in the laboratory and implanted by doctors in the US. Continue reading

Scientists grow cartilage to reconstruct nose

Scientists grow cartilage to reconstruct nose

Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Continue reading

Laboratory-grown vaginas implanted in patients

Laboratory-grown vaginas implanted in patients

Scientists reported today the first human recipients of laboratory-grown vaginal organs. A research team led by Anthony Atala, M.D., director of Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine, describes in the Lancet long-term success in four teenage girls who received vaginal organs that were engineered with their own cells. “This pilot study is the first to demonstrate that vaginal organs can be constructed in the lab and used successfully in humans,” said Atala. Continue reading

Laboratory-grown vaginas implanted in patients

Laboratory-grown vaginas implanted in patients

Scientists reported today the first human recipients of laboratory-grown vaginal organs. A research team led by Anthony Atala, M.D., director of Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine, describes in the Lancet long-term success in four teenage girls who received vaginal organs that were engineered with their own cells. “This pilot study is the first to demonstrate that vaginal organs can be constructed in the lab and used successfully in humans,” said Atala. Continue reading

Genome sequencing of MRSA infection predicts disease severity

Genome sequencing of MRSA infection predicts disease severity

The spread of the antibiotic-resistant pathogen MRSA (methicillin-resistant Staphylococcus aureus ) remains a concerning public health problem, especially among doctors trying to determine appropriate treatment options for infected patients. Bacterial pathogens, such as MRSA, cause disease in part due to toxicity, or the bacterium’s ability to damage a host’s tissue. Continue reading

Bad penny: Cancer’s thirst for copper can be targeted

Bad penny: Cancer’s thirst for copper can be targeted

Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report. The researchers found that cancers with a mutation in the BRAF gene require copper to promote tumor growth. These tumors include melanoma, the most dangerous form of skin cancer that kills an estimated 10,000 people in the United States a year, according to the National Cancer Institute. Continue reading

DNA modifications measured in blood signal related changes in the brain

DNA modifications measured in blood signal related changes in the brain

Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone — and showing signs of anxiety — are directly related to changes found in their brain tissues. The proof-of-concept study, reported online ahead of print in the June issue of Psychoneuroendocrinology , offers what the research team calls the first evidence that epigenetic changes that alter the way genes function without changing their underlying DNA sequence — and are detectable in blood — mirror alterations in brain tissue linked to underlying psychiatric diseases. The new study reports only on so-called epigenetic changes to a single stress response gene called FKBP5, which has been implicated in depression, bipolar disorder and post-traumatic stress disorder Continue reading