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Tag Archives: Medical

Proteins conspire to make breast cancer cells resistant to drug treatment

Proteins conspire to make breast cancer cells resistant to drug treatment

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) provide compelling and conclusive evidence that antiestrogen resistance in breast cancer cells requires the interaction between proteins called BCAR1 and BCAR3. In the study, published in the Journal of Biological Chemistry , the researchers also identified a signaling pathway that is crucial for drug resistance mediated by this protein complex Continue reading

Proteins conspire to make breast cancer cells resistant to drug treatment

Proteins conspire to make breast cancer cells resistant to drug treatment

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) provide compelling and conclusive evidence that antiestrogen resistance in breast cancer cells requires the interaction between proteins called BCAR1 and BCAR3. In the study, published in the Journal of Biological Chemistry , the researchers also identified a signaling pathway that is crucial for drug resistance mediated by this protein complex Continue reading

Some immune cells defend only one organ

Some immune cells defend only one organ

Scientists have uncovered a new way the immune system may fight cancers and viral infections. The finding could aid efforts to use immune cells to treat illness. Continue reading

Scientists re-define what’s healthy in newest analysis for human microbiome project

Scientists re-define what’s healthy in newest analysis for human microbiome project

As scientists catalog the trillions of bacteria found in every nook and cranny of the human body, a new look by the University of Michigan shows wide variation in the types of bacteria found in healthy people. Continue reading

HIV-positive women respond well to HPV vaccine, study shows

HIV-positive women respond well to HPV vaccine, study shows

HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial. Continue reading

Antibiotics improve growth in children in developing countries

Antibiotics improve growth in children in developing countries

Antibiotics improve growth in children at risk of undernourishment in low and middle income countries, according to researchers at McGill University who have just conducted a research literature review on the subject. Their results, published in the British Medical Journal , suggest that the youngest children from the most vulnerable populations benefit most and show significant improvements toward expected growth for their age and sex, particularly for weight. Malnutrition in early childhood, reflected in poor growth, is the cause of nearly half of all mortality worldwide in children less than five years old. Continue reading

New standards proposed for gauging muscle decline in older adults

New standards proposed for gauging muscle decline in older adults

Sarcopenia — the age-related loss of muscle mass and strength — may put up to 50 percent of seniors at greater risk for disability, yet there is no consensus within the medical community for how this condition should be measured. However, a new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences (volume 69, number 5) lays out an empirically derived set of criteria for diagnosing sarcopenia. These recommendations are a result of the Foundation for the National Institutes of Health Biomarkers Consortium Sarcopenia Project, which includes scientists and grantees from the National Institutes of Health, along with other partners in government, academia, and the private sector. Continue reading

Fiber-optic microscope will help physicians detect cancer, diseases at early stages

Fiber-optic microscope will help physicians detect cancer, diseases at early stages

An engineering researcher at the University of Arkansas has developed an inexpensive, endoscopic microscope capable of producing high-resolution, sub-cellular images of tissue in real time. The fiber-optic device, which is portable, re-usable and easily packaged with conventional endoscopes, will help clinicians detect and diagnose early-stage disease, primarily cancer. Continue reading

Sharpening microscope images: New technique takes cues from astronomy, ophthalmology

Sharpening microscope images: New technique takes cues from astronomy, ophthalmology

The complexity of biology can befuddle even the most sophisticated light microscopes. Continue reading

New combination drug therapy proves very effective in hepatitis C treatments

New combination drug therapy proves very effective in hepatitis C treatments

Treatment options for the 170 million people worldwide with chronic Hepatitis C Virus (HCV) are evolving rapidly, although the available regimens often come with significant side effects. Two multi-center clinical trials led by Beth Israel Deaconess Medical Center show promise for a new option that could help lead to both an increase in patients cured with a much more simple and tolerable all oral therapy Continue reading