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Leukaemia caused by chromosome catastrophe

Leukaemia caused by chromosome catastrophe

Researchers have found that people born with a rare abnormality of their chromosomes have a 2,700-fold increased risk of a rare childhood leukemia. In this abnormality, two specific chromosomes are fused together but become prone to catastrophic shattering. Continue reading

Leukaemia caused by chromosome catastrophe

Leukaemia caused by chromosome catastrophe

Researchers have found that people born with a rare abnormality of their chromosomes have a 2,700-fold increased risk of a rare childhood leukemia. In this abnormality, two specific chromosomes are fused together but become prone to catastrophic shattering. Continue reading

New method can diagnose feared pancreatic cancer

New method can diagnose feared pancreatic cancer

Pancreatic cancer is often detected at a late stage, which results in poor prognosis and limited treatment options. Researchers at The University od Gothenburg, Sweden, have now developed a method which identifies the cancer’s visible precursors with 97% certainty. Continue reading

Surprising new way to kill cancer cells

Surprising new way to kill cancer cells

Northwestern Medicine scientists have demonstrated that cancer cells — and not normal cells — can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand. “The discovery seems counterintuitive because CD95 has previously been defined as a tumor suppressor,” said lead investigator Marcus Peter, professor in medicine-hematology/Oncology at Northwestern University Feinberg School of Medicine. “But when we removed it from cancer cells, rather than proliferate, they died.” The findings were published March 20 in Cell Reports Continue reading

Preterm children at increased risk of having math problems

Preterm children at increased risk of having math problems

Researchers have found that preterm children are at an increased risk of having general cognitive and mathematic problems. The new study by the University of Warwick and Ruhr-University Bochum, published in the Journal of Pediatrics , sought to understand the relationship between preterm birth and dyscalculia. Dyscalculia, a learning disorder which involves frequent problems with everyday arithmetic tasks, is diagnosed when children do worse in maths than would be expected based on their general intelligence Continue reading

Preterm children at increased risk of having math problems

Preterm children at increased risk of having math problems

Researchers have found that preterm children are at an increased risk of having general cognitive and mathematic problems. The new study by the University of Warwick and Ruhr-University Bochum, published in the Journal of Pediatrics , sought to understand the relationship between preterm birth and dyscalculia. Continue reading

Improved pavement markings can save lives

Improved pavement markings can save lives

As spring finally emerges after a ferocious winter, our battered roads will soon be re-exposed. While potholes and cracks might make news, a larger concern should be the deterioration to pavement markings, from yellow to white lines, which are a major factor in preventing traffic accidents. A study from Concordia University, funded by Infrastructure Canada and published in Structure and Infrastructure Engineering, found that snowplows are the biggest culprit in erasing roadway markings Continue reading

Inflammation mobilizes tumor cells, study shows

Inflammation mobilizes tumor cells, study shows

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis. Malignant tumors pose a major threat to survival largely because they shed mobile cells that can form secondary tumors in other tissues. This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues Continue reading

Inflammation mobilizes tumor cells, study shows

Inflammation mobilizes tumor cells, study shows

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis. Malignant tumors pose a major threat to survival largely because they shed mobile cells that can form secondary tumors in other tissues. This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues Continue reading

Potential New Therapeutic Target for Controlling High Blood Sugar

Potential New Therapeutic Target for Controlling High Blood Sugar

A UT Southwestern Medical Center study has identified a new potential therapeutic target for controlling high blood sugar, a finding that could help the estimated 25 million Americans with type 2 diabetes. Researchers showed that lipid molecules called phosphatidic acids enhance glucose production in the liver. These findings suggest that inhibiting or reducing production of phosphatidic acids may do the opposite Continue reading