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Guidelines can predict early menopause in child cancer survivors, giving hope for fertility

Guidelines can predict early menopause in child cancer survivors, giving hope for fertility

Girls with cancer who are most likely to become infertile after treatment can be identified using guidelines developed almost 20 years ago, new research shows. Continue reading

New ways to treat solid tumors using protein

New ways to treat solid tumors using protein

An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumor effects. As EphA3 is present in normal organs only during embryonic development but is expressed in blood cancers and in solid tumors, this antibody-based approach may be a suitable candidate treatment for solid tumors. The researchers from Monash University and Ludwig Cancer Research, in Australia, and KaloBios Pharmaceuticals, in the US, have had their findings published in the journal Cancer Research . Continue reading

Cell discovery brings blood disorder cure closer

Cell discovery brings blood disorder cure closer

A cure for a range of blood disorders and immune diseases is in sight, according to scientists who have unravelled the mystery of stem cell generation. Continue reading

Elusive viral ‘machine’ architecture finally rendered

Elusive viral ‘machine’ architecture finally rendered

For half a century biologists have studied the way that the lambda virus parks DNA in the chromosome of a host E. coli bacterium and later extracts it as a model reaction of genetic recombination. Continue reading

Preemies’ gut bacteria may depend more on gestational age than environment

Preemies’ gut bacteria may depend more on gestational age than environment

Scientists believe babies are born with digestive systems containing few or no bacteria. Their guts then quickly become colonized by microbes — good and bad — as they nurse or take bottles, receive medication and even as they are passed from one adoring relative to another. However, in infants born prematurely, researchers at Washington University School of Medicine in St. Continue reading

‘Worm pill’ could ease autoimmune disease symptoms

‘Worm pill’ could ease autoimmune disease symptoms

Experts believe a molecule in parasitic worms could help explain why worm infections can effectively treat a range of autoimmune diseases, including multiple sclerosis, psoriasis, rheumatoid arthritis and lupus. The Monash University study, published in the FASEB Journal , successfully identified peptides from parasitic worms that suppress the body’s immune response. Researchers believe this could pave the way for a new drug containing the peptide to provide relief from the symptoms of autoimmune diseases. Continue reading

‘Dimmer switch’ drug idea could tackle schizophrenia without side effects

‘Dimmer switch’ drug idea could tackle schizophrenia without side effects

Discovery of a new mechanism of drug action could lead to the next generation of drugs to treat schizophrenia. Continue reading

Natural light in office boosts health

Natural light in office boosts health

Office workers with more light exposure at the office had longer sleep duration, better sleep quality, more physical activity and better quality of life compared to office workers with less light exposure in the workplace, reports a new study from Northwestern Medicine and the University of Illinois at Urbana-Champaign. The study highlights the importance of exposure to natural light to employee health and the priority architectural designs of office environments should place on natural daylight exposure for workers, the study authors said. Employees with windows in the workplace received 173 percent more white light exposure during work hours and slept an average of 46 minutes more per night than employees who did not have the natural light exposure in the workplace. Continue reading

New culprit identified in metabolic syndrome

New culprit identified in metabolic syndrome

A new study suggests uric acid may play a role in causing metabolic syndrome, a cluster of risk factors that increases the risk of heart disease and type 2 diabetes. Uric acid is a normal waste product removed from the body by the kidneys and intestines and released in urine and stool. Continue reading

Type 2 diabetics can live longer than people without the disease

Type 2 diabetics can live longer than people without the disease

Patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition, a large-scale study involving over 180,000 people has shown. Continue reading