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Cancer-fighting cocktail demonstrates promising results as treatment for advanced cervical cancer

Cancer-fighting cocktail demonstrates promising results as treatment for advanced cervical cancer

Combining a standard chemotherapy drug with a second drug that stops cells from dividing improves both the survival and response rates for those with advanced cervical cancer, a new study by UT Southwestern Medical Center cancer researchers finds. The cancer-fighting cocktail, which combines the chemotherapy drug cisplatin with pemetrexed — an agent that stops cancer cells from dividing — showed promising results for advanced, persistent, or recurrent cervical cancer. “We found that pemetrexed combined with cisplatin is less toxic, well tolerated, and should be developed for further treatment of cervical cancer,” said gynecologic oncology specialist Dr. Continue reading

New producer of crucial vitamin B12 discovered

New producer of crucial vitamin B12 discovered

New research has determined that a single group of micro-organisms may be responsible for much of the world’s vitamin B 12 production in the oceans, with implications for the global carbon cycle and climate change. Continue reading

In wake of uproar over Facebook’s emotional manipulation study, bioethics scholars say new rules are ‘moral imperative’

In wake of uproar over Facebook’s emotional manipulation study, bioethics scholars say new rules are ‘moral imperative’

In a digital world where many adults remember a time before personal computers and the internet existed, its not surprising that ethics policies and practices are still catching up to the technology, acknowledge an international team of research ethics scholars in Proceedings of the National Academy of Sciences (PNAS). Continue reading

No innocent bystander: Cartilage contributes to arthritis

No innocent bystander: Cartilage contributes to arthritis

Melbourne researchers have discovered that cartilage plays an active role in the destruction and remodelling of joints seen in rheumatoid arthritis, rather than being an ‘innocent bystander’ as previously thought. Dr Tommy Liu, Professor Ian Wicks, Dr Kate Lawlor, Dr Ben Croker and colleagues from the Walter and Eliza Hall Institute made the discovery while investigating the role of the protein SOCS3 in controlling inflammation during rheumatoid arthritis. The study was published in the journal Arthritis and Rheumatology Continue reading

Experts call for massive global response to tackle Ebola

Experts call for massive global response to tackle Ebola

The current Ebola outbreak now requires a ‘rapid response at a massive global scale,’ according to experts. Continue reading

Dendritic cells affect onset, progress of psoriasis

Dendritic cells affect onset, progress of psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine . Continue reading

Quarter of people with diabetes worldwide live in China, but new approach could help transform their care

Quarter of people with diabetes worldwide live in China, but new approach could help transform their care

Diabetes has become a major public health crisis in China, with an annual projected cost of 360 billion RMB (nearly 35 billion British pounds) by 2030, but a new collaborative approach to care that uses registries and community support could help improve diabetes care, according to a new three-part Series about diabetes in China published in The Lancet Diabetes & Endocrinology . China has the largest number of people with diabetes of any country in the world, and the disease has reached epidemic proportions in the adult population Continue reading

Halving the risk of preterm birth for some twin pregnancies

Halving the risk of preterm birth for some twin pregnancies

International research involving the University of Adelaide has found that the risk of preterm birth could be halved for a specific group of “super high-risk” twin pregnancies. The results could help to save babies’ lives throughout the world and prevent serious health complications after birth. The study, involving researchers from the University of Adelaide’s Robinson Research Institute, reviewed all of the previous large studies conducted into the use of progestogen hormones, which have been trialed over the past 10 years to help prevent preterm birth in twins. Continue reading

Re-analysis of clinical trial data can change conclusions in one-third of studies

Re-analysis of clinical trial data can change conclusions in one-third of studies

As many as one-third of previously published randomized clinical trials could be re-analyzed in ways that modify the conclusions of how many or what types of patients need to be treated, according to a new study by researchers at the Stanford University School of Medicine. A culture that fails to encourage data sharing makes such re-analysis of the data extremely rare, the researchers said. They were able to identify only 37 published re-analyses over more than three decades of research. Continue reading

Statins may protect against microvascular complications of diabetes

Statins may protect against microvascular complications of diabetes

The development of common diabetes complications that can lead to blindness and amputations could be reduced by taking statins, indicates new research published in The Lancet Diabetes & Endocrinology. It is well established that statins via cholesterol lowering effectively reduce the risks of heart attack and stroke in people with type 2 diabetes, but whether statin use affects the development of small blood vessel (or microvascular) complications, such as eye, nerve, and kidney disease in individuals with diabetes is not known. “Since high levels of blood glucose, the hallmark of diabetes, are linked with microvascular disease, and since statins are suspected of raising glucose levels, we tested the hypothesis that individuals taking a statin before a diagnosis of diabetes might be at increased risk of developing microvascular complications,” explains study author Professor Børge G Nordestgaard, Chief Physician in Clinical Biochemistry at Copenhagen University Hospital in Denmark. Continue reading