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Dormant Viruses Re-Emerge in Patients with Lingering Sepsis, Signaling Immune Suppression

Dormant Viruses Re-Emerge in Patients with Lingering Sepsis, Signaling Immune Suppression

A provocative study links prolonged episodes of sepsis — a life-threatening infection and leading cause of death in hospitals — to the reactivation of otherwise dormant viruses in the body. In healthy people, such latent viruses are kept in check by the immune system. But a study by a team at Washington University School of Medicine in St Continue reading

Sports teams may lose out from having ‘too much talent’

Sports teams may lose out from having ‘too much talent’

As the FIFA World Cup kicks off and the NBA finals “heat” up, new research suggests that there is such a thing as having too much talent on a sports team. The research indicates that, after a certain point, the addition of more superstar talent to a team can actually be detrimental, resulting in poorer team performance Continue reading

Inside the adult ADHD brain: Differences between adults who have recovered, and those who have not

Inside the adult ADHD brain: Differences between adults who have recovered, and those who have not

About 11 percent of school-age children in the United States have been diagnosed with attention deficit hyperactivity disorder (ADHD). While many of these children eventually “outgrow” the disorder, some carry their difficulties into adulthood: About 10 million American adults are currently diagnosed with ADHD. Continue reading

Malaria-carrying mosquitoes wiped out in lab with genetic method that creates male-only offspring

Malaria-carrying mosquitoes wiped out in lab with genetic method that creates male-only offspring

Scientists have modified mosquitoes to produce sperm that will only create males, pioneering a fresh approach to eradicating malaria. In a study published in the journal Nature Communications , scientists from Imperial College London have tested a new genetic method that distorts the sex ratio of Anopheles gambiae mosquitoes, the main transmitters of the malaria parasite, so that the female mosquitoes that bite and pass the disease to humans are no longer produced. Continue reading

Quest for long-lasting blood: Scientists developing one-size-fits-all artifical blood

Quest for long-lasting blood: Scientists developing one-size-fits-all artifical blood

A team of scientists at the University of Essex are hoping to develop a one-size-fits-all, third generation artificial blood substitute. Every day thousands of people around the world have their lives saved or improved thanks to someone giving blood. But imagine how many more lives could be saved if a long-lasting blood substitute could be found, which could easily be stored at room temperature and available to all patients, regardless of their blood type Continue reading

Biologists pave the way for improved epilepsy treatments

Biologists pave the way for improved epilepsy treatments

University of Toronto biologists leading an investigation into the cells that regulate proper brain function, have identified and located the key players whose actions contribute to afflictions such as epilepsy and schizophrenia. The discovery is a major step toward developing improved treatments for these and other neurological disorders. “Neurons in the brain communicate with other neurons through synapses, communication that can either excite or inhibit other neurons,” said Professor Melanie Woodin in the Department of Cell and Systems Biology at the University of Toronto (U of T), lead investigator of a study published today in Cell Reports Continue reading

Shorter TB treatment regimens will reduce cost for patients, families

Shorter TB treatment regimens will reduce cost for patients, families

Shorter tuberculosis treatment regimens will reduce the out-of-pocket expenses incurred by both patients and their family members, who often act as the patients’ guardians. Continue reading

Elucidating pathogenic mechanism of meningococcal meningitis

Elucidating pathogenic mechanism of meningococcal meningitis

Neisseria meningitidis, also called meningococcus, is a bacterium responsible for meningitis and septicemia. Continue reading

Hemorrhagic Fevers Can Be Caused by Body’s Antiviral Interferon Response

Hemorrhagic Fevers Can Be Caused by Body’s Antiviral Interferon Response

Hemorrhagic fevers caused by Lassa, dengue and other viruses affect more than one million people annually and are often fatal, yet scientists have never understood why only some virus-infected people come down with the disease and others do not. But now, virologists and immunologists at The Scripps Research Institute (TSRI) have found a major clue to the mystery of “hemorrhagic fever” syndromes Continue reading

Hemorrhagic Fevers Can Be Caused by Body’s Antiviral Interferon Response

Hemorrhagic Fevers Can Be Caused by Body’s Antiviral Interferon Response

Hemorrhagic fevers caused by Lassa, dengue and other viruses affect more than one million people annually and are often fatal, yet scientists have never understood why only some virus-infected people come down with the disease and others do not. But now, virologists and immunologists at The Scripps Research Institute (TSRI) have found a major clue to the mystery of “hemorrhagic fever” syndromes. In findings reported this week in an Early Edition of the Proceedings of the National Academy of Sciences , the team showed that Interferon Type I (IFN-I) immune proteins are key drivers of a viral syndrome in mice that closely mimics these human hemorrhagic fevers Continue reading