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Dendritic cells affect onset, progress of psoriasis

Dendritic cells affect onset, progress of psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine . Continue reading

Quarter of people with diabetes worldwide live in China, but new approach could help transform their care

Quarter of people with diabetes worldwide live in China, but new approach could help transform their care

Diabetes has become a major public health crisis in China, with an annual projected cost of 360 billion RMB (nearly 35 billion British pounds) by 2030, but a new collaborative approach to care that uses registries and community support could help improve diabetes care, according to a new three-part Series about diabetes in China published in The Lancet Diabetes & Endocrinology . China has the largest number of people with diabetes of any country in the world, and the disease has reached epidemic proportions in the adult population Continue reading

Halving the risk of preterm birth for some twin pregnancies

Halving the risk of preterm birth for some twin pregnancies

International research involving the University of Adelaide has found that the risk of preterm birth could be halved for a specific group of “super high-risk” twin pregnancies. The results could help to save babies’ lives throughout the world and prevent serious health complications after birth. The study, involving researchers from the University of Adelaide’s Robinson Research Institute, reviewed all of the previous large studies conducted into the use of progestogen hormones, which have been trialed over the past 10 years to help prevent preterm birth in twins. Continue reading

Re-analysis of clinical trial data can change conclusions in one-third of studies

Re-analysis of clinical trial data can change conclusions in one-third of studies

As many as one-third of previously published randomized clinical trials could be re-analyzed in ways that modify the conclusions of how many or what types of patients need to be treated, according to a new study by researchers at the Stanford University School of Medicine. A culture that fails to encourage data sharing makes such re-analysis of the data extremely rare, the researchers said. They were able to identify only 37 published re-analyses over more than three decades of research. Continue reading

Statins may protect against microvascular complications of diabetes

Statins may protect against microvascular complications of diabetes

The development of common diabetes complications that can lead to blindness and amputations could be reduced by taking statins, indicates new research published in The Lancet Diabetes & Endocrinology. It is well established that statins via cholesterol lowering effectively reduce the risks of heart attack and stroke in people with type 2 diabetes, but whether statin use affects the development of small blood vessel (or microvascular) complications, such as eye, nerve, and kidney disease in individuals with diabetes is not known. “Since high levels of blood glucose, the hallmark of diabetes, are linked with microvascular disease, and since statins are suspected of raising glucose levels, we tested the hypothesis that individuals taking a statin before a diagnosis of diabetes might be at increased risk of developing microvascular complications,” explains study author Professor Børge G Nordestgaard, Chief Physician in Clinical Biochemistry at Copenhagen University Hospital in Denmark. Continue reading

Prediabetes increases the risk of cancer by 15 percent, study of almost 900,000 people shows

Prediabetes increases the risk of cancer by 15 percent, study of almost 900,000 people shows

A meta-analysis comprising 16 studies and 891,426 participants from various regions of the world shows that prediabetes increases the risk of cancer by 15%, with differing risks depending on the type of cancer. The study, published in Diabetologia (the journal of the European Association for the Study of Diabetes) is by Professor Yuli Huang, The First People’s Hospital of Shunde, Daliang Town, Shunde District, China, and colleagues Continue reading

Targeting protein-making machinery to stop harmful bacteria

Targeting protein-making machinery to stop harmful bacteria

One challenge in killing off harmful bacteria is that many of them develop a resistance to antibiotics. Continue reading

Drug therapies, parent training help children with ADHD, severe aggression

Drug therapies, parent training help children with ADHD, severe aggression

Prescribing both a stimulant and an antipsychotic drug to children with physical aggression and attention-deficit/hyperactivity disorder (ADHD), along with teaching parents to use behavior management techniques, reduces aggressive and serious behavioral problems in children, according to a study conducted by researchers in the Department of Psychiatry at Stony Brook University School of Medicine. The findings are published in the September issue of the Journal of the American Academy of Child and Adolescent Psychiatry . Continue reading

Household air pollution puts more than one in three people worldwide at risk of ill health, early death

Household air pollution puts more than one in three people worldwide at risk of ill health, early death

Household air pollution, caused by the use of plant-based or coal fuel for cooking, heating, and lighting, is putting nearly three billion people worldwide at risk of ill health and early death, according to a new Commission, published in The Lancet Respiratory Medicine journal. Continue reading

Taxes, subsidies could encourage healthier diet, lower healthcare costs

Taxes, subsidies could encourage healthier diet, lower healthcare costs

In a Viewpoint published in the Journal of the American Medical Association , a team of Boston researchers call for the implementation of taxes and subsidies to improve dietary quality in the United States. The researchers from the Friedman School of Nutrition Science and Policy at Tufts University, Harvard University and Boston Children’s Hospital write that policies taxing nearly all packaged foods and subsidizing healthier foods could both help people make meaningful dietary changes and substantially reduce health care costs Continue reading