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Preterm children at increased risk of having math problems

Preterm children at increased risk of having math problems

Researchers have found that preterm children are at an increased risk of having general cognitive and mathematic problems. The new study by the University of Warwick and Ruhr-University Bochum, published in the Journal of Pediatrics , sought to understand the relationship between preterm birth and dyscalculia. Continue reading

Improved pavement markings can save lives

Improved pavement markings can save lives

As spring finally emerges after a ferocious winter, our battered roads will soon be re-exposed. While potholes and cracks might make news, a larger concern should be the deterioration to pavement markings, from yellow to white lines, which are a major factor in preventing traffic accidents. A study from Concordia University, funded by Infrastructure Canada and published in Structure and Infrastructure Engineering, found that snowplows are the biggest culprit in erasing roadway markings Continue reading

Inflammation mobilizes tumor cells, study shows

Inflammation mobilizes tumor cells, study shows

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis. Malignant tumors pose a major threat to survival largely because they shed mobile cells that can form secondary tumors in other tissues. This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues Continue reading

Inflammation mobilizes tumor cells, study shows

Inflammation mobilizes tumor cells, study shows

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis. Malignant tumors pose a major threat to survival largely because they shed mobile cells that can form secondary tumors in other tissues. This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues Continue reading

Potential New Therapeutic Target for Controlling High Blood Sugar

Potential New Therapeutic Target for Controlling High Blood Sugar

A UT Southwestern Medical Center study has identified a new potential therapeutic target for controlling high blood sugar, a finding that could help the estimated 25 million Americans with type 2 diabetes. Researchers showed that lipid molecules called phosphatidic acids enhance glucose production in the liver. These findings suggest that inhibiting or reducing production of phosphatidic acids may do the opposite Continue reading

Potential New Therapeutic Target for Controlling High Blood Sugar

Potential New Therapeutic Target for Controlling High Blood Sugar

A UT Southwestern Medical Center study has identified a new potential therapeutic target for controlling high blood sugar, a finding that could help the estimated 25 million Americans with type 2 diabetes. Researchers showed that lipid molecules called phosphatidic acids enhance glucose production in the liver. These findings suggest that inhibiting or reducing production of phosphatidic acids may do the opposite Continue reading

Child ADHD stimulant medication use leads to BMI rebound in late adolescence

Child ADHD stimulant medication use leads to BMI rebound in late adolescence

A new study from researchers at Johns Hopkins Bloomberg School of Public Health found that children treated with stimulants for attention deficit hyperactivity disorder (ADHD) experienced slower body mass index (BMI) growth than their undiagnosed or untreated peers, followed by a rapid rebound of BMI that exceeded that of children with no history of ADHD or stimulant use and that could continue to obesity. The study, thought to be the most comprehensive analysis of ADHD and stimulant use in children to date, found that the earlier the medication began, and the longer the medication was taken, the slower the BMI growth in earlier childhood but the more rapid the BMI rebound in late adolescence, typically after discontinuation of medication. Researchers concluded that stimulant use, and not a diagnosis of ADHD, was associated with higher BMI and obesity. Continue reading

Follow the ant trail for drug design: Ant behavior inspires software design

Follow the ant trail for drug design: Ant behavior inspires software design

The path to developing new drugs is a long one. Continue reading

Bacterial reporters that get the scoop: Engineered gut bacteria ‘remembers’ what it saw

Bacterial reporters that get the scoop: Engineered gut bacteria ‘remembers’ what it saw

It’s a jungle in there. Continue reading

Pathways that direct immune system to turn ‘on’ or ‘off’ found

Pathways that direct immune system to turn ‘on’ or ‘off’ found

A key discovery explaining how components of the immune system determine whether to activate or to suppress the immune system, made by Kelvin Lee, MD, Professor of Oncology and Co-Leader of the Tumor Immunology and Immunotherapy Program at Roswell Park Cancer Institute (RPCI), and colleagues led to published findings being selected as the “Paper of the Week” by the Journal of Biological Chemistry (JBC). Continue reading