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Dosage of HIV drug may be ineffective for half of African-Americans

Dosage of HIV drug may be ineffective for half of African-Americans

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. Continue reading

Supplements of calcium, vitamin D may have too much for some older women

Supplements of calcium, vitamin D may have too much for some older women

Calcium and vitamin D are commonly recommended for older women, but the usual supplements may send calcium excretion and blood levels too high for some women, shows a new study published online in Menopause , the journal of The North American Menopause Society. This randomized, placebo-controlled trial included 163 older (ages 57 to 90) white women whose vitamin D levels were too low. The women took calcium citrate tablets to meet their recommended intake of 1,200 mg/day, and they took various doses of vitamin D, ranging from 400 to 4,800 IU/day Continue reading

Responses with crizotinib in MET-amplified lung cancer show new targetable form of disease

Responses with crizotinib in MET-amplified lung cancer show new targetable form of disease

A study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2014 reports the results of a first-in-human, phase 1 dose escalation trial of crizotinib (XALKORI) in 14 patients with advanced, MET-amplified non-small cell lung cancer (NCT00585195). In 2011, the drug crizotinib earned accelerated approval by the US FDA to target the subset of advanced non-small cell lung cancers caused by rearrangements of the anaplastic lymphoma kinase (ALK) gene, and subsequently was granted regular approval in 2013 Continue reading

New standards proposed for gauging muscle decline in older adults

New standards proposed for gauging muscle decline in older adults

Sarcopenia — the age-related loss of muscle mass and strength — may put up to 50 percent of seniors at greater risk for disability, yet there is no consensus within the medical community for how this condition should be measured. However, a new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences (volume 69, number 5) lays out an empirically derived set of criteria for diagnosing sarcopenia. These recommendations are a result of the Foundation for the National Institutes of Health Biomarkers Consortium Sarcopenia Project, which includes scientists and grantees from the National Institutes of Health, along with other partners in government, academia, and the private sector. Continue reading

New standards proposed for gauging muscle decline in older adults

New standards proposed for gauging muscle decline in older adults

Sarcopenia — the age-related loss of muscle mass and strength — may put up to 50 percent of seniors at greater risk for disability, yet there is no consensus within the medical community for how this condition should be measured. However, a new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences (volume 69, number 5) lays out an empirically derived set of criteria for diagnosing sarcopenia Continue reading

Levels of sodium intake recommended by CDC associated with harmful health outcomes

Levels of sodium intake recommended by CDC associated with harmful health outcomes

A new study published in the American Journal of Hypertension finds evidence that the average daily sodium intake of most Americans is actually associated with better health outcomes than intake levels currently recommended by the CDC and major health departments, which are now being viewed by many in the scientific community as excessively and unrealistically low. Continue reading

Smaller Snacking is Smart Snacking: New study shows ‘just a bite’ will satisfy

Smaller Snacking is Smart Snacking: New study shows ‘just a bite’ will satisfy

Jan. Continue reading

Trust ‘operated on wrong patient’

Trust ‘operated on wrong patient’

23 November 2012 Last updated at 07:54 ET A health watchdog is taking action against a Cambridgeshire hospital trust which performed eye surgery on the wrong person. Cambridge University Hospitals NHS Foundation Trust performed four botched operations, including leaving instruments inside two people Continue reading

Leisure-time physical activity extends life expectancy as much as 4.5 years

Leisure-time physical activity extends life expectancy as much as 4.5 years

ScienceDaily (Nov. 6, 2012) — Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the National Cancer Institute (NCI), part of the National Institutes of Health. The study, which found that people who engaged in leisure-time physical activity had life expectancy gains of as much as 4.5 years, appeared Nov Continue reading

Cranberry juice now unlikely to prevent cystitis, review finds

Cranberry juice now unlikely to prevent cystitis, review finds

ScienceDaily (Oct. 16, 2012) — Cranberry juice is unlikely to prevent bladder and kidney infections, according to an updated systematic review published in The Cochrane Library Continue reading