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Tag Archives: Research

Real-time tracking system developed to monitor dangerous bacteria inside body

Real-time tracking system developed to monitor dangerous bacteria inside body

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections with a class of dangerous Gram-negative bacteria. These increasingly drug-resistant bacteria are responsible for a range of diseases, including fatal pneumonias and various bloodstream or solid-organ infections acquired in and outside the hospital. “What we have produced is essentially a system that localizes the epicenter of infection and provides real-time tracking of bacterial activity, giving us rapid feedback on how the bacteria respond to antibiotics,” says principal investigator Sanjay Jain, M.D., an infectious disease specialist at the Johns Hopkins Children’s Center and director of the Center for Inflammation Imaging and Research at Johns Hopkins Continue reading

Hospital logs staggering 2.5 million alarms in just a month

Hospital logs staggering 2.5 million alarms in just a month

Following the study of a hospital that logged more than 2.5 million patient monitoring alarms in just one month, researchers at UC San Francisco have, for the first time, comprehensively defined the detailed causes as well as potential solutions for the widespread issue of alarm fatigue in hospitals. Their study is in the Oct. 22 issue of PLOS ONE and available online Continue reading

Fast modeling of cancer mutations

Fast modeling of cancer mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process. MIT researchers have now developed a new way to model the effects of these genetic mutations in mice Continue reading

How lymph nodes expand during disease

How lymph nodes expand during disease

CANCER RESEARCH UK and UCL scientists have discovered that the same specialised immune cells that patrol the body and spot infections also trigger the expansion of immune organs called lymph nodes, according to a study published in Nature . Continue reading

Competition keeps health-care costs low, U.S. researchers find

Competition keeps health-care costs low, U.S. researchers find

Medical practices in less competitive health-care markets charge more for services, according to a study conducted by researchers at the Stanford University School of Medicine and the National Bureau of Economic Research. The study, based on U.S Continue reading

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Smoking interferes with neurocognitive recovery during abstinence from alcohol

Numerous studies have shown that individuals with an alcohol use disorder perform worse than those without one on multiple neurocognitive domains of function following detoxification from alcohol, although the level of impairment can vary widely among individuals. A new study of the degree of neurocognitive recovery in treatment-seeking alcohol dependent individuals (ALC) — with varied degrees of smoking status — during the first eight months of sustained abstinence from alcohol has found that smoking status influenced the rate and level of recovery Continue reading

Overweight women lose in the labor market, study finds

Overweight women lose in the labor market, study finds

Overweight women are more likely to work in lower-paying and more physically demanding jobs; less likely to get higher-wage positions that include interaction with the public; and make less money in either case compared to average size women and all men, according to a new Vanderbilt study. Continue reading

How troubled marriage, depression history promote obesity

How troubled marriage, depression history promote obesity

The double-whammy of marital hostility and a history of depression can increase the risk for obesity in adults by altering how the body processes high-fat foods, according to new research. In the study, men and women with a history of depression whose arguments with spouses were especially heated showed several potential metabolic problems after eating a high-fat meal. They burned fewer calories and had higher levels of insulin and spikes of triglycerides — a form of fat in the blood — after eating a heavy meal when compared to participants without these risk factors. Continue reading

In disease outbreak management, flexibility can save lives, money

In disease outbreak management, flexibility can save lives, money

A new approach for responding to and managing disease outbreaks is being proposed by a team of epidemiologists led by two Penn State University researchers. The team’s flexible approach could save many lives and millions of dollars. The approach, called “adaptive management,” allows decision-makers to use knowledge they gain during an outbreak to update ongoing interventions with the goal of containing outbreaks more quickly and efficiently. Continue reading