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Mitochondria’s role in neurodegenerative diseases clearer thanks to mouse study

Mitochondria’s role in neurodegenerative diseases clearer thanks to mouse study

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses. Researchers led by Janet Shaw, Ph.D., professor of biochemistry, found that when healthy, functioning mitochondria was prevented from moving along axons — nerve fibers that conduct electricity away from neurons — mice developed symptoms of neurodegenerative diseases. Continue reading

Exercise boosts tumor-fighting ability of chemotherapy, team finds

Exercise boosts tumor-fighting ability of chemotherapy, team finds

Study after study has proven it true: exercise is good for you. But new research from University of Pennsylvania scientists suggests that exercise may have an added benefit for cancer patients undergoing chemotherapy. Their work, performed in a mouse model of melanoma, found that combining exercise with chemotherapy shrunk tumors more than chemotherapy alone. Continue reading

Living in disadvantaged neighborhood worsens musculoskeletal pain outcomes after trauma exposure

Living in disadvantaged neighborhood worsens musculoskeletal pain outcomes after trauma exposure

Individuals living in disadvantaged neighborhoods have worse musculoskeletal pain outcomes over time after stressful events such as motor vehicle collision than individuals from higher socioeconomic status neighborhoods, even after accounting for individual characteristics such as age, sex, income, education, and employment status. These were the findings of a multi-site research study led by Samuel McLean, MD, MPH, associate professor of anesthesiology and emergency medicine at the University of North Carolina School of Medicine. Continue reading

Testosterone therapy should only be for men with hypogonadism, experts say

Testosterone therapy should only be for men with hypogonadism, experts say

The Endocrine Society testified today at a meeting of the Food and Drug Administration (FDA) discussing the appropriate population for testosterone replacement therapy and the potential for adverse cardiovascular outcomes associated with its use. Though testosterone use has sharply increased among older men in the past decade, the Society told the FDA that testosterone therapy should be limited to men who meet the diagnostic guidelines for hypogonadism. Testosterone is a key male sex hormone involved in maintaining sex drive, sperm production and bone health. Continue reading

Benefits, risks of yoga found for bipolar disorder

Benefits, risks of yoga found for bipolar disorder

Right now no one can say whether yoga provides clinical benefits to people with bipolar disorder, but in a new article in the Journal of Psychiatric Practice , researchers report survey responses they gathered from scores of people with the condition who practice yoga. What the collective testimony suggests is that yoga can be a substantial help, but it sometimes carries risks, too. “There is no scientific literature on hatha yoga for bipolar disorder,” said lead author Lisa Uebelacker, associate professor (research) of psychiatry and human behavior in the Alpert Medical School of Brown University and a staff psychologist at Butler Hospital. Continue reading

Healthy humans make nice homes for viruses

Healthy humans make nice homes for viruses

The same viruses that make us sick can take up residence in and on the human body without provoking a sneeze, cough or other troublesome symptom, according to new research at Washington University School of Medicine in St. Louis. Continue reading

Healthy humans make nice homes for viruses

Healthy humans make nice homes for viruses

The same viruses that make us sick can take up residence in and on the human body without provoking a sneeze, cough or other troublesome symptom, according to new research at Washington University School of Medicine in St. Louis. Continue reading

Combining Epilepsy Drug, Morphine Can Result in Less Pain, Lower Opioid Doses

Combining Epilepsy Drug, Morphine Can Result in Less Pain, Lower Opioid Doses

Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University. The result could bring significant relief to many patients with neuropathic pain, a difficult-to-treat condition often felt in the arms and legs and associated with nerve tissue damage. Continue reading

Slow to mature, quick to distract: ADHD brain study finds slower development of key connections

Slow to mature, quick to distract: ADHD brain study finds slower development of key connections

A peek inside the brains of more than 750 children and teens reveals a key difference in brain architecture between those with attention deficit hyperactivity disorder and those without. Kids and teens with ADHD, a new study finds, lag behind others of the same age in how quickly their brains form connections within, and between, key brain networks. Continue reading

Walking or cycling to work improves wellbeing, researchers find

Walking or cycling to work improves wellbeing, researchers find

A report reveals that people who stopped driving and started walking or cycling to work benefited from improved wellbeing. In particular, active commuters felt better able to concentrate and were less under strain than if they travelled by car Continue reading