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Tag Archives: Scientists

Program predicts placement of chemical tags that control gene activity

Program predicts placement of chemical tags that control gene activity

Biochemists working at the University of California, San Diego, have developed a program that predicts the placement of chemical marks that control the activity of genes based on sequences of DNA. They describe their analysis and report results from its application to human embryonic cells in a paper published in Nature Methods online September 21. “All of our cells have the same blueprint, the same DNA, although they serve separate functions,” said John Whitaker, lead author of the report Continue reading

‘Immortal’ flatworms: Weapon against bacteria

‘Immortal’ flatworms: Weapon against bacteria

A novel mode of defense against bacteria such as the causal agent of tuberculosis or Staphylococcus aureus has been identified in humans by studying a small, aquatic flatworm, the planarian. This discovery was made by scientists in the “Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes” (CNRS/IRD/Inserm/Aix-Marseille Université), working in collaboration with the “Centre Méditerranéen de Médecine Moléculaire” (Inserm/Université Nice Sophia Antipolis) and other national and international research groups Continue reading

Avatars make the Internet sign to deaf people

Avatars make the Internet sign to deaf people

It is challenging for deaf people to learn a sound-based language, since they are physically not able to hear those sounds. Hence, most of them struggle with written language as well as with text reading and comprehension. Continue reading

Encyclopedia of how genomes function gets much bigger

Encyclopedia of how genomes function gets much bigger

A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The research, appearing August 28 in in the journal Nature, compares how the information encoded in the three species’ genomes is “read out,” and how their DNA and proteins are organized into chromosomes. The results add billions of entries to a publicly available archive of functional genomic data Continue reading

Mimicking natural evolution with ‘promiscuous reactions’ to improve the diversity of drugs

Mimicking natural evolution with ‘promiscuous reactions’ to improve the diversity of drugs

The researchers, who report their findings online in the journal Nature Chemistry , took their inspiration from evolution in nature. The research may uncover new pharmaceutical drugs that traditional methods would never have found. “Nature produces some amazing structures with really interesting biological activity, but the plant or animal did not design them. Continue reading

Potential risk factors for urinary tract infections in young girls

Potential risk factors for urinary tract infections in young girls

Young girls with an intense, red, itchy rash on their outer genital organs may be at increased risk of developing urinary tract infections (UTIs), according to new research from Wake Forest Baptist Medical Center. The treatment may be as simple as better hygiene and avoiding potential irritants such as bubble baths and swimming pools Continue reading

Seals and sea lions likely spread tuberculosis to humans

Seals and sea lions likely spread tuberculosis to humans

Tuberculosis is one of the most persistent and deadliest infectious diseases in the world, killing one to two million people each year. Scientists who study tuberculosis have long debated its origins Continue reading

Personal, public costs of scientific misconduct calculated

Personal, public costs of scientific misconduct calculated

Much has been assumed about the private and public damage of scientific misconduct. Yet few have tried to measure the costs to perpetrators and to society. A recent study calculated some of the career impacts, as well as federal funding wasted, when biomedical research papers are retracted Continue reading

Newborns’ genetic code sends infection distress signal

Newborns’ genetic code sends infection distress signal

Babies suffering from life-threatening bacterial infections such as sepsis could benefit from improved treatment, thanks to a ground-breaking study. For the first time, researchers have been able to detect and decode a signal generated from a baby’s DNA that can tell doctors whether or not a bacterial infection is present in the bloodstream. Continue reading

Scientists boost potential of passive immunization against HIV

Scientists boost potential of passive immunization against HIV

Scientists are pursuing injections or intravenous infusions of broadly neutralizing HIV antibodies (bNAbs) as a strategy for preventing HIV infection. This technique, called passive immunization, has been shown to protect monkeys from a monkey form of HIV called simian human immunodeficiency virus, or SHIV. To make passive immunization a widely feasible HIV prevention option for people, scientists want to modify bNAbs such that a modest amount of them is needed only once every few months. Continue reading